Functional proteomic analysis, a missing piece for understanding clonal evolution and cooperation in the tissue microecology

Single-cell high-dimensional imaging mass cytometry: one step beyond in oncology

(2023) Yaël Glasson et al.   Seminars in Immunopathology

AKT/mTOR signaling modulates resistance to endocrine therapy and CDK4/6 inhibition in metastatic breast cancers

(2023) Maysa M. Abu-Khalaf et al.   npj Precision Oncology

Next generation pan-cancer blood proteome profiling using proximity extension assay

(2023) María Bueno Álvez et al.   Nature Communications

Unbiased spatial proteomics with single-cell resolution in tissues

(2022) Andreas Mund et al.   MOLECULAR CELL

High p16 expression and heterozygous RB1 loss are biomarkers for CDK4/6 inhibitor resistance in ER+ breast cancer

(2022) Marta Palafox et al.   Nature Communications

Automated annotation and visualisation of high-resolution spatial proteomic mass spectrometry imaging data using HIT-MAP

(2021) G. Guo et al.   Nature Communications

Functional Mapping of AKT Signaling and Biomarkers of Response from the FAIRLANE Trial of Neoadjuvant Ipatasertib plus Paclitaxel for Triple-Negative Breast Cancer

(2021) Zhen Shi et al.   CLINICAL CANCER RESEARCH

Laser Capture Proteomics: spatial tissue molecular profiling from the bench to personalized medicine

(2021) Lance A. Liotta et al.   Expert Review of Proteomics

Automated mass spectrometry imaging of over 2000 proteins from tissue sections at 100-μm spatial resolution

(2020) Paul D. Piehowski et al.   Nature Communications

Molecular profiling for precision cancer therapies

(2020) Eoghan R. Malone et al.   Genome Medicine

Lineage plasticity in cancer: a shared pathway of therapeutic resistance

(2020) Álvaro Quintanal-Villalonga et al.   Nature Reviews Clinical Oncology

Molecular Landscape and Actionable Alterations in a Genomically Guided Cancer Clinical Trial: National Cancer Institute Molecular Analysis for Therapy Choice (NCI-MATCH)

(2020) Keith T. Flaherty et al.   JOURNAL OF CLINICAL ONCOLOGY

Spatial proteomics: a powerful discovery tool for cell biology

(2019) Emma Lundberg et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

FAIRLANE, a double-blind placebo-controlled randomized phase II trial of neoadjuvant ipatasertib plus paclitaxel for early triple-negative breast cancer

(2019) M Oliveira et al.   ANNALS OF ONCOLOGY

Resistance mechanisms to osimertinib in EGFR-mutated non-small cell lung cancer

(2019) Alessandro Leonetti et al.   BRITISH JOURNAL OF CANCER

Tumour heterogeneity and resistance to cancer therapies

(2017) Ibiayi Dagogo-Jack et al.   Nature Reviews Clinical Oncology

Metastatic castration-resistant prostate cancer reveals intrapatient similarity and interpatient heterogeneity of therapeutic kinase targets

(2013) J. M. Drake et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

(2012) Marco Gerlinger et al.   NEW ENGLAND JOURNAL OF MEDICINE