Lychnopholide loaded in surface modified polylactide nanocapsules (LYC-PLA-PEG-NC) cure mice infected by Trypanosoma cruzi strain a prototype of resistance to benznidazole and nifurtimox: First insights of its mechanism of action

Lychnopholide in PLA-PEG nanocapsules cures infection by drug resistant Trypanosoma cruzi strain in acute and chronic phases

(2020) Renata Tupinambá Branquinho et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Activity of the sesquiterpene lactone goyazensolide against Trypanosoma cruzi in vitro and in vivo

(2019) Matheus Marques Milagre et al.   PARASITOLOGY

Functional polylactide via ring-opening copolymerisation with allyl, benzyl and propargyl glycidyl ethers

(2017) Gwenaelle Pound-Lana et al.   EUROPEAN POLYMER JOURNAL

Increased Body Exposure to New Anti-Trypanosomal Through Nanoencapsulation

(2017) Renata Tupinambá Branquinho et al.   Scientific Reports

Biodegradable Polymeric Nanocapsules Prevent Cardiotoxicity of Anti-Trypanosomal Lychnopholide

(2017) Renata Tupinambá Branquinho et al.   Scientific Reports

Efficacy of Lychnopholide Polymeric Nanocapsules after Oral and Intravenous Administration in Murine Experimental Chagas Disease

(2016) Carlos Geraldo Campos de Mello et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Nitroheterocyclic drugs cure experimental Trypanosoma cruzi infections more effectively in the chronic stage than in the acute stage

(2016) Amanda Fortes Francisco et al.   Scientific Reports

Polymeric nanocapsules prevent oxidation of core-loaded molecules: evidence based on the effects of docosahexaenoic acid and neuroprostane on breast cancer cells proliferation

(2015) Jérôme Roy et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Revisiting the Posttherapeutic Cure Criterion in Chagas Disease: Time for New Methods, More Questions, Doubts, and Polemics or Time to Change Old Concepts?

(2015) Marta de Lana et al.   Biomed Research International

Sesquiterpene Lactone in Nanostructured Parenteral Dosage Form Is Efficacious in Experimental Chagas Disease

(2014) Renata Tupinambá Branquinho et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Drug discovery for Chagas disease should consider Trypanosoma cruzi strain diversity

(2014) Bianca Zingales et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Real-time PCR strategy for parasite quantification in blood and tissue samples of experimental Trypanosoma cruzi infection

(2012) Sérgio Caldas et al.   ACTA TROPICA

HPLC-DAD and UV-Spectrophotometry for the Determination of Lychnopholide in Nanocapsule Dosage Form: Validation and Application to Release Kinetic Study

(2012) R. T. Branquinho et al.   JOURNAL OF CHROMATOGRAPHIC SCIENCE

Toxicological evaluation of ethanolic extract of Lychnophora trichocarpha, Brazilian arnica

(2012) Fernanda C. Ferrari et al.   Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy

In-house ELISA method to analyze anti-Trypanosoma cruzi IgG reactivity for differential diagnosis and evaluation of Chagas disease morbidity

(2012) Lilian da Silva Santos et al.   Revista da Sociedade Brasileira de Medicina Tropical

Trypanosoma cruzi and Chagas' Disease in the United States

(2011) C. Bern et al.   CLINICAL MICROBIOLOGY REVIEWS

In vitro and in vivo experimental models for drug screening and development for Chagas disease

(2010) Alvaro José Romanha et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Chagas disease: A Latin American health problem becoming a world health problem

(2009) Gabriel A. Schmunis et al.   ACTA TROPICA

Predicting prognosis in patients with Chagas disease: Why are the results of various studies so different?

(2009) Anis Rassi et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Epidemiology, control and surveillance of Chagas disease: 100 years after its discovery

(2009) José Rodrigues Coura et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Present situation and new strategies for Chagas disease chemotherapy: a proposal

(2009) José Rodrigues Coura   MEMORIAS DO INSTITUTO OSWALDO CRUZ

A new consensus for Trypanosoma cruzi intraspecific nomenclature: second revision meeting recommends TcI to TcVI

(2009) B Zingales et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ