Rapamycin promotes hematoma resorption and enhances endothelial cell function by suppressing the mTOR/STAT3 signaling in chronic subdural hematoma

mTOR inhibition prevents angiotensin II–induced aortic rupture and pseudoaneurysm but promotes dissection in Apoe-deficient mice

(2022) Changshun He et al.   JCI Insight

Neuroprotective Effect of Chrysophanol as a PI3K/AKT/mTOR Signaling Inhibitor in an Experimental Model of Autologous Blood-induced Intracerebral Hemorrhage

(2022) Kuldeep Singh Jadaun et al.   Current Medical Science

Synergistic effects of Rapamycin and Fluorouracil to treat a gastric tumor in a PTEN conditional deletion mouse model

(2021) Cong-hui Zhu et al.   Gastric Cancer

Atorvastatin combined with dexamethasone promote hematoma absorption in an optimized rat model of chronic subdural hematoma

(2021) Dong Wang et al.   Aging-US

Evaluation of the efficacy of atorvastatin in the treatment for chronic subdural hematoma: a meta-analysis

(2020) Chang He et al.   NEUROSURGICAL REVIEW

Eugenol Attenuates Cerebral Ischemia-Reperfusion Injury by Enhancing Autophagy via AMPK-mTOR-P70S6K Pathway

(2020) Xiaowei Sun et al.   Frontiers in Pharmacology

Resveratrol potentiates the anti-tumor effects of rapamycin in papillary thyroid cancer: PI3K/AKT/mTOR pathway involved

(2020) Peng Bian et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Targeting STAT3 in Cancer Immunotherapy

(2020) Sailan Zou et al.   Molecular Cancer

Middle Meningeal Artery Embolization for Chronic Subdural Hematoma

(2020) Joshua S. Catapano et al.   Frontiers in Neurology

Rapamycin alleviates cognitive impairment in murine vascular dementia: The enhancement of mitophagy by PI3K/AKT/mTOR axis

(2020) Guimin Zheng et al.   TISSUE & CELL

Middle Meningeal Artery Embolization for Chronic Subdural Hematomas: Cautious Optimism for a Challenging Pathology

(2019) Paul Foreman et al.   World Neurosurgery

Rapamycin improves bone mass in high-turnover osteoporosis with iron accumulation through positive effects on osteogenesis and angiogenesis

(2019) Jiadong Wu et al.   BONE

Treatment of Relapsed Chronic Subdural Hematoma in Four Young Children with Atorvastatin and Low‐dose Dexamethasone

(2019) Jinhao Huang et al.   PHARMACOTHERAPY

Rapamycin-Loaded Leukosomes Reverse Vascular Inflammation

(2019) Christian Boada et al.   CIRCULATION RESEARCH

Effects of Atorvastatin on Surgical Treatments of Chronic Subdural Hematoma

(2018) Rongrui Tang et al.   World Neurosurgery

Safety and Efficacy of Atorvastatin for Chronic Subdural Hematoma in Chinese Patients

(2018) Rongcai Jiang et al.   JAMA Neurology

Pathophysiology of chronic subdural haematoma: inflammation, angiogenesis and implications for pharmacotherapy

(2017) Ellie Edlmann et al.   Journal of Neuroinflammation

Inhibitory Mechanism of the Outer Membrane Growth of Chronic Subdural Hematomas

(2017) Koji Osuka et al.   JOURNAL OF NEUROTRAUMA

Rapamycin Ameliorates Experimental Autoimmune Encephalomyelitis by Suppressing the mTOR-STAT3 Pathway

(2017) Huiqing Hou et al.   NEUROCHEMICAL RESEARCH

Systemic administration of cell-free exosomes generated by human bone marrow derived mesenchymal stem cells cultured under 2D and 3D conditions improves functional recovery in rats after traumatic brain injury

(2017) Yanlu Zhang et al.   NEUROCHEMISTRY INTERNATIONAL

Activation of Signal Transducer and Activator of Transcription 3 in Endothelial Cells of Chronic Subdural Hematoma Outer Membranes

(2016) Koji Osuka et al.   World Neurosurgery

Blood-brain barrier leakage after status epilepticus in rapamycin-treated rats I: Magnetic resonance imaging

(2015) Erwin A. van Vliet et al.   EPILEPSIA

Blood-brain barrier leakage after status epilepticus in rapamycin-treated rats II: Potential mechanisms

(2015) Erwin A. van Vliet et al.   EPILEPSIA

Rapamycin increases neuronal survival, reduces inflammation and astrocyte proliferation after spinal cord injury

(2015) Yona Goldshmit et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Rapamycin-Induced Apoptosis in HGF-Stimulated Lens Epithelial Cells by AKT/mTOR, ERK and JAK2/STAT3 Pathways

(2014) Fang Tian et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Chronic subdural haematoma: modern management and emerging therapies

(2014) Angelos G. Kolias et al.   Nature Reviews Neurology

Activation of JAK-STAT3 signaling pathway in chronic subdural hematoma outer membranes

(2012) Koji Osuka et al.   NEUROSCIENCE LETTERS