IL‐27 produced during acute malaria infection regulates Plasmodium‐specific memory CD4+ T cells

A CD4+ T cell reference map delineates subtype-specific adaptation during acute and chronic viral infections

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Interpretation of T cell states from single-cell transcriptomics data using reference atlases

(2021) Massimo Andreatta et al.   Nature Communications

Plasma levels of interleukin 27 in falciparum malaria is increased independently of co-infection with HIV: potential immune-regulatory role during malaria

(2020) Kari Otterdal et al.   BMC INFECTIOUS DISEASES

KLRG1+ Memory CD8 T Cells Combine Properties of Short-Lived Effectors and Long-Lived Memory

(2020) Kristin R. Renkema et al.   JOURNAL OF IMMUNOLOGY

Host‐pathogen interaction in the tissue environment during Plasmodium blood‐stage infection

(2020) Katsuyuki Yui et al.   PARASITE IMMUNOLOGY

Transcriptome dynamics of CD4+ T cells during malaria maps gradual transit from effector to memory

(2020) Megan S. F. Soon et al.   NATURE IMMUNOLOGY

The Emergence and Functional Fitness of Memory CD4+ T Cells Require the Transcription Factor Thpok

(2019) Thomas Ciucci et al.   IMMUNITY

Role of IL-10 in inhibiting protective immune responses against infection with heterologous Plasmodium parasites

(2019) Sayuri Nakamae et al.   PARASITOLOGY INTERNATIONAL

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

(2019) Yingyao Zhou et al.   Nature Communications

The regulation of CD4 + T cells during malaria

(2019) Rajiv Kumar et al.   IMMUNOLOGICAL REVIEWS

Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1+ Stem-like CD8+ T Cells during Chronic Infection

(2019) William H. Hudson et al.   IMMUNITY

Activation and IL-10 production of specific CD4+ T cells are regulated by IL-27 during chronic infection with Plasmodium chabaudi

(2019) Odsuren Sukhbaatar et al.   PARASITOLOGY INTERNATIONAL

The role of cytokines in T-cell memory in health and disease

(2018) Miro E. Raeber et al.   IMMUNOLOGICAL REVIEWS

Recent Insights into CD4+Th Cell Differentiation in Malaria

(2018) Megan S. F. Soon et al.   JOURNAL OF IMMUNOLOGY

Protection by and maintenance of CD4 effector memory and effector T cell subsets in persistent malaria infection

(2018) Michael M. Opata et al.   PLoS Pathogens

Dimensionality reduction for visualizing single-cell data using UMAP

(2018) Etienne Becht et al.   NATURE BIOTECHNOLOGY

Emerging concepts in T follicular helper cell responses to malaria

(2017) Diana S. Hansen et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Development of a Novel CD4+TCR Transgenic Line That Reveals a Dominant Role for CD8+Dendritic Cells and CD40 Signaling in the Generation of Helper and CTL Responses to Blood-Stage Malaria

(2017) Daniel Fernandez-Ruiz et al.   JOURNAL OF IMMUNOLOGY

Interleukin-27-Producing CD4 + T Cells Regulate Protective Immunity during Malaria Parasite Infection

(2016) Daisuke Kimura et al.   IMMUNITY

Somatically Hypermutated Plasmodium-Specific IgM+ Memory B Cells Are Rapid, Plastic, Early Responders upon Malaria Rechallenge

(2016) Akshay T. Krishnamurty et al.   IMMUNITY

Chronic Plasmodium chabaudi Infection Generates CD4 Memory T Cells with Increased T Cell Receptor Sensitivity but Poor Secondary Expansion and Increased Apoptosis

(2016) Michael M. Opata et al.   INFECTION AND IMMUNITY

The Immunobiology of Interleukin-27

(2015) Hiroki Yoshida et al.   Annual Review of Immunology

Malaria Immunity in Man and Mosquito: Insights into Unsolved Mysteries of a Deadly Infectious Disease

(2014) Peter D. Crompton et al.   Annual Review of Immunology

Gradual Decline in Malaria-Specific Memory T Cell Responses Leads to Failure to Maintain Long-Term Protective Immunity to Plasmodium chabaudi AS Despite Persistence of B Cell Memory and Circulating Antibody

(2014) A. P. Freitas do Rosario et al.   JOURNAL OF IMMUNOLOGY

Deficiency in EBV-induced gene 3 (EBI3) in MRL/lprmice results in pathological alteration of autoimmune glomerulonephritis and sialadenitis

(2014) Takashi Igawa et al.   Modern Rheumatology

IL-27 and IL-27-producing CD4+ T cells in human tuberculous pleural effusion

(2014) Huan Xia et al.   TUBERCULOSIS

Effector-like CD8+ T Cells in the Memory Population Mediate Potent Protective Immunity

(2013) Janelle A. Olson et al.   IMMUNITY

IL-27 Receptor Signaling Regulates Memory CD4+T Cell Populations and Suppresses Rapid Inflammatory Responses during Secondary Malaria Infection

(2013) Emily Gwyer Findlay et al.   INFECTION AND IMMUNITY

IL-27 Receptor Signalling Restricts the Formation of Pathogenic, Terminally Differentiated Th1 Cells during Malaria Infection by Repressing IL-12 Dependent Signals

(2013) Ana Villegas-Mendez et al.   PLoS Pathogens

Interleukin-27: Balancing Protective and Pathological Immunity

(2012) Christopher A. Hunter et al.   IMMUNITY

Follicular Helper CD4 T Cells (TFH)

(2011) Shane Crotty   Annual Review of Immunology

Differential Expression of Ly6C and T-bet Distinguish Effector and Memory Th1 CD4+ Cell Properties during Viral Infection

(2011) Heather D. Marshall et al.   IMMUNITY

An Interleukin-21- Interleukin-10-STAT3 Pathway Is Critical for Functional Maturation of Memory CD8+ T Cells

(2011) Weiguo Cui et al.   IMMUNITY

Cell biology and immunology of malaria

(2011) Julius Clemence Hafalla et al.   IMMUNOLOGICAL REVIEWS

Origins of CD4+ effector and central memory T cells

(2011) Marion Pepper et al.   NATURE IMMUNOLOGY

The contribution of Plasmodium chabaudi to our understanding of malaria

(2011) Robin Stephens et al.   TRENDS IN PARASITOLOGY

Type I Interferons Regulate Cytolytic Activity of Memory CD8+ T Cells in the Lung Airways during Respiratory Virus Challenge

(2010) Jacob E. Kohlmeier et al.   IMMUNITY

Essential Role for IL-27 Receptor Signaling in Prevention of Th1-Mediated Immunopathology during Malaria Infection

(2010) E. G. Findlay et al.   JOURNAL OF IMMUNOLOGY

Effector Memory Th1 CD4 T Cells Are Maintained in a Mouse Model of Chronic Malaria

(2010) Robin Stephens et al.   PLoS Pathogens

Acquired Immunity to Malaria

(2009) D. L. Doolan et al.   CLINICAL MICROBIOLOGY REVIEWS

Memory CD4 T cells emerge from effector T-cell progenitors

(2008) Laurie E. Harrington et al.   NATURE

Immunity to malaria: more questions than answers

(2008) Jean Langhorne et al.   NATURE IMMUNOLOGY