Impact of metformin and Dysosmobacter welbionis on diet-induced obesity and diabetes: from clinical observation to preclinical intervention

The gut microbiota in obesity and weight management: microbes as friends or foe?

(2023) Matthias Van Hul et al.   Nature Reviews Endocrinology

Gut microbiome and health: mechanistic insights

(2022) Willem M de Vos et al.   GUT

A β-N-acetylhexosaminidase Amuc_2109 from Akkermansia muciniphila protects against dextran sulfate sodium-induced colitis in mice by enhancing intestinal barrier and modulating gut microbiota

(2022) Kaiyue Qian et al.   Food & Function

Physical activity enhances the improvement of body mass index and metabolism by inulin: a multicenter randomized placebo-controlled trial performed in obese individuals

(2022) Julie Rodriguez et al.   BMC Medicine

Akkermansia muciniphila: paradigm for next-generation beneficial microorganisms

(2022) Patrice D. Cani et al.   Nature Reviews Gastroenterology & Hepatology

The Effect of Prebiotics and Oral Anti-Diabetic Agents on Gut Microbiome in Patients with Type 2 Diabetes: A Systematic Review and Network Meta-Analysis of Randomised Controlled Trials

(2022) Omorogieva Ojo et al.   Nutrients

Prebiotic dietary fibre intervention improves fecal markers related to inflammation in obese patients: results from the Food4Gut randomized placebo-controlled trial

(2021) Audrey M. Neyrinck et al.   EUROPEAN JOURNAL OF NUTRITION

A newly identified protein from Akkermansia muciniphila stimulates GLP-1 secretion

(2021) Patrice D. Cani et al.   Cell Metabolism

Dysosmobacter welbionis is a newly isolated human commensal bacterium preventing diet-induced obesity and metabolic disorders in mice

(2021) Tiphaine Le Roy et al.   GUT

Discovery of the gut microbial signature driving the efficacy of prebiotic intervention in obese patients

(2020) Julie Rodriguez et al.   GUT

Link between gut microbiota and health outcomes in inulin -treated obese patients: Lessons from the Food4Gut multicenter randomized placebo-controlled trial

(2020) Sophie Hiel et al.   CLINICAL NUTRITION

Gut bacteria Akkermansia is associated with reduced risk of obesity: evidence from the American Gut Project

(2020) Qi Zhou et al.   Nutrition & Metabolism

Butyrate mediates anti-inflammatory effects of Faecalibacterium prausnitzii in intestinal epithelial cells through Dact3

(2020) Marion Lenoir et al.   Gut Microbes

Effects of Metformin on the Gut Microbiota in Obesity and Type 2 Diabetes Mellitus

(2020) Qi Zhang et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

Dysosmobacter welbionis gen. nov., sp. nov., isolated from human faeces and emended description of the genus Oscillibacter

(2019) Tiphaine Le Roy et al.   INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Metformin

(2018) Julie Rodriguez et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Understanding the Representative Gut Microbiota Dysbiosis in Metformin-Treated Type 2 Diabetes Patients Using Genome-Scale Metabolic Modeling

(2018) Dorines Rosario et al.   Frontiers in Physiology

Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug

(2017) Hao Wu et al.   NATURE MEDICINE

Gut microbiota — at the intersection of everything?

(2017) Patrice D. Cani   Nature Reviews Gastroenterology & Hepatology

Metformin Is Associated With Higher Relative Abundance of Mucin-DegradingAkkermansia muciniphilaand Several Short-Chain Fatty Acid–Producing Microbiota in the Gut

(2016) Jacobo de la Cuesta-Zuluaga et al.   DIABETES CARE

Adipose Tissue Remodeling: Its Role in Energy Metabolism and Metabolic Disorders

(2016) Sung Sik Choe et al.   Frontiers in Endocrinology

Microbiome of prebiotic-treated mice reveals novel targets involved in host response during obesity

(2014) Amandine Everard et al.   ISME Journal

An increase in theAkkermansiaspp. population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice

(2013) Na-Ri Shin et al.   GUT

A metagenome-wide association study of gut microbiota in type 2 diabetes

(2012) Junjie Qin et al.   NATURE

Responses of Gut Microbiota and Glucose and Lipid Metabolism to Prebiotics in Genetic Obese and Diet-Induced Leptin-Resistant Mice

(2011) Amandine Everard et al.   DIABETES

Regulation of Lipolysis in Small and Large Fat Cells of the Same Subject

(2011) Jurga Laurencikiene et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM