SHIP1 inhibition via 3-alpha-amino-cholestane enhances protection against Leishmania infection

Leishmania intercepts IFN-γR signaling at multiple levels in macrophages

(2022) Dhiraj Gurjar et al.   CYTOKINE

Transcription Factors Interplay Orchestrates the Immune-Metabolic Response of Leishmania Infected Macrophages

(2021) Haifa Bichiou et al.   Frontiers in Cellular and Infection Microbiology

The drug resistance mechanisms in Leishmania donovani are independent of immunosuppression

(2020) Baibaswata Saha et al.   CYTOKINE

Conundrums in leishmaniasis

(2020) Baibaswata Saha et al.   CYTOKINE

Leishmania parasitophorous vacuole membranes display phosphoinositides that create conditions for continuous Akt activation and a target for miltefosine in Leishmania infections.

(2018) Naixin Zhang et al.   CELLULAR MICROBIOLOGY

Targeting SHIP-1 in Myeloid Cells Enhances Trained Immunity and Boosts Response to Infection

(2018) Paula Saz-Leal et al.   Cell Reports

Dual enhancement of T and NK cell function by pulsatile inhibition of SHIP1 improves antitumor immunity and survival

(2017) Matthew Gumbleton et al.   Science Signaling

Dual enhancement of T and NK cell function by pulsatile inhibition of SHIP1 improves antitumor immunity and survival

(2017) Matthew Gumbleton et al.   Science Signaling

Coordinate Expansion of Murine Hematopoietic and Mesenchymal Stem Cell Compartments by SHIPi

(2015) R. Brooks et al.   STEM CELLS

SHIPi Enhances Autologous and Allogeneic Hematopoietic Stem Cell Transplantation

(2015) Sandra Fernandes et al.   EBioMedicine

SHP-1 Plays a Crucial Role in CD40 Signaling Reciprocity

(2014) Tabish Hasan Khan et al.   JOURNAL OF IMMUNOLOGY

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(2012) Gwenny Fuhler et al.   MOLECULAR MEDICINE

Inhibitor and activator: dual functions for SHIP in immunity and cancer

(2010) William G. Kerr   Annals of the New York Academy of Sciences

SHIP deficiency causes Crohn's disease-like ileitis

(2010) W. G. Kerr et al.   GUT

The p110  Isoform of Phosphatidylinositol 3-Kinase Controls Susceptibility to Leishmania major by Regulating Expansion and Tissue Homing of Regulatory T Cells

(2009) D. Liu et al.   JOURNAL OF IMMUNOLOGY