Sculpting the dendritic landscape: Actin, microtubules, and the art of arborization

Microtubule polarity is instructive for many aspects of neuronal polarity

(2022) Pankajam Thyagarajan et al.   DEVELOPMENTAL BIOLOGY

Mechanisms of microtubule organization in differentiated animal cells

(2022) Anna Akhmanova et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The branching code: A model of actin-driven dendrite arborization

(2022) Tomke Stürner et al.   Cell Reports

Right place, right time - Spatial guidance of neuronal morphogenesis by septin GTPases

(2022) Megan R. Radler et al.   CURRENT OPINION IN NEUROBIOLOGY

Dynamic instability of dendrite tips generates the highly branched morphologies of sensory neurons

(2022) Sonal Shree et al.   Science Advances

PTRN-1 (CAMSAP) and NOCA-2 (NINEIN) are required for microtubule polarity in Caenorhabditis elegans dendrites

(2022) Liu He et al.   PLOS BIOLOGY

PP2A phosphatase regulates cell-type specific cytoskeletal organization to drive dendrite diversity

(2022) Shatabdi Bhattacharjee et al.   Frontiers in Molecular Neuroscience

Microtubules, actin and cytolinkers: how to connect cytoskeletons in the neuronal growth cone

(2021) Rita Pinto-Costa et al.   NEUROSCIENCE LETTERS

To nucleate or not, that is the question in neurons

(2021) Alexis T. Weiner et al.   NEUROSCIENCE LETTERS

A systematic analysis of microtubule‐destabilizing factors during dendrite pruning in Drosophila

(2021) Shufeng Bu et al.   EMBO REPORTS

A two-step actin polymerization mechanism drives dendrite branching

(2021) Rebecca Shi et al.   Neural Development

Microtubule organization of vertebrate sensory neurons in vivo

(2021) Matthew Shorey et al.   DEVELOPMENTAL BIOLOGY

Microtubule Minus-End Binding Protein CAMSAP2 and Kinesin-14 Motor KIFC3 Control Dendritic Microtubule Organization

(2020) Yujie Cao et al.   CURRENT BIOLOGY

Protein phosphatase PP2A regulates microtubule orientation and dendrite pruning in Drosophila

(2020) Menglong Rui et al.   EMBO REPORTS

PP2A phosphatase is required for dendrite pruning via actin regulation in Drosophila

(2020) Neele Wolterhoff et al.   EMBO REPORTS

Atypical Myosin Tunes Dendrite Arbor Subdivision

(2020) Li-Foong Yoong et al.   NEURON

Endosomal Wnt signaling proteins control microtubule nucleation in dendrites

(2020) Alexis T. Weiner et al.   PLOS BIOLOGY

Cortical anchoring of the microtubule cytoskeleton is essential for neuron polarity

(2020) Liu He et al.   eLife

Kinetochore proteins suppress neuronal microtubule dynamics and promote dendrite regeneration

(2020) James I. Hertzler et al.   MOLECULAR BIOLOGY OF THE CELL

Growth cone-localized microtubule organizing center establishes microtubule orientation in dendrites

(2020) Xing Liang et al.   eLife

Distinct Microtubule Organizing Center Mechanisms Combine to Generate Neuron Polarity and Arbor Complexity

(2020) Oliver R. Wilkes et al.   Frontiers in Cellular Neuroscience

Achieving functional neuronal dendrite structure through sequential stochastic growth and retraction

(2020) André Ferreira Castro et al.   eLife

Deterministic and Stochastic Rules of Branching Govern Dendrite Morphogenesis of Sensory Neurons

(2020) Amrutha Palavalli et al.   CURRENT BIOLOGY

Kinetochore Proteins Have a Post-Mitotic Function in Neurodevelopment

(2019) Guoli Zhao et al.   DEVELOPMENTAL CELL

The Kinetochore-Microtubule Coupling Machinery Is Repurposed in Sensory Nervous System Morphogenesis

(2019) Dhanya K. Cheerambathur et al.   DEVELOPMENTAL CELL

Functions of Microtubule Disassembly during Neurite Pruning

(2019) Sebastian Rumpf et al.   TRENDS IN CELL BIOLOGY

Patronin governs minus-end-out orientation of dendritic microtubules to promote dendrite pruning in Drosophila

(2019) Yan Wang et al.   eLife

Actin assembly and non-muscle myosin activity drive dendrite retraction in an UNC-6/Netrin dependent self-avoidance response

(2019) Lakshmi Sundararajan et al.   PLoS Genetics

Cytoskeletal makeup of the synapse: Shaft versus spine

(2019) Michael Bucher et al.   Cytoskeleton

A Dendritic Guidance Receptor Complex Brings Together Distinct Actin Regulators to Drive Efficient F-Actin Assembly and Branching

(2018) Wei Zou et al.   DEVELOPMENTAL CELL

Cell-Autonomous Regulation of Dendrite Self-Avoidance by the Wnt Secretory Factor MIG-14/Wntless

(2018) Chien-Po Liao et al.   NEURON

The Actin Cytoskeleton and Actin-Based Motility

(2018) Tatyana Svitkina   Cold Spring Harbor Perspectives in Biology

APC2 controls dendrite development by promoting microtubule dynamics

(2018) Olga I. Kahn et al.   Nature Communications

MTSS1 Regulation of Actin-Nucleating Formin DAAM1 in Dendritic Filopodia Determines Final Dendritic Configuration of Purkinje Cells

(2018) Kelly Kawabata Galbraith et al.   Cell Reports

Actin blobs prefigure dendrite branching sites

(2018) Vanitha Nithianandam et al.   JOURNAL OF CELL BIOLOGY

Local microtubule organization promotes cargo transport in C. elegans dendrites

(2018) Martin Harterink et al.   JOURNAL OF CELL SCIENCE

Microtubule-severing enzymes: From cellular functions to molecular mechanism

(2018) Francis J. McNally et al.   JOURNAL OF CELL BIOLOGY

Dendritic Cytoskeletal Architecture Is Modulated by Combinatorial Transcriptional Regulation in Drosophila melanogaster

(2017) Ravi Das et al.   GENETICS

Dendritic Actin Cytoskeleton: Structure, Functions, and Regulations

(2017) Anja Konietzny et al.   Frontiers in Cellular Neuroscience

Dendritic Cytoskeletal Architecture Is Modulated by Combinatorial Transcriptional Regulation in Drosophila melanogaster

(2017) Ravi Das et al.   GENETICS

Dendrites In Vitro and In Vivo Contain Microtubules of Opposite Polarity and Axon Formation Correlates with Uniform Plus-End-Out Microtubule Orientation

(2016) K. W. Yau et al.   JOURNAL OF NEUROSCIENCE

Actin and Actin-Binding Proteins

(2016) Thomas D. Pollard   Cold Spring Harbor Perspectives in Biology

Development of Dendritic Form and Function

(2015) Julie L. Lefebvre et al.   Annual Review of Cell and Developmental Biology

Coordinating Neuronal Actin–Microtubule Dynamics

(2015) Charlotte H. Coles et al.   CURRENT BIOLOGY

Profilin-1 Serves as a Gatekeeper for Actin Assembly by Arp2/3-Dependent and -Independent Pathways

(2015) Jeremy D. Rotty et al.   DEVELOPMENTAL CELL

Profilin Regulates F-Actin Network Homeostasis by Favoring Formin over Arp2/3 Complex

(2015) Cristian Suarez et al.   DEVELOPMENTAL CELL

MIM-Induced Membrane Bending Promotes Dendritic Spine Initiation

(2015) Juha Saarikangas et al.   DEVELOPMENTAL CELL

Dendrite arborization requires the dynein cofactor NudE

(2015) A. L. Arthur et al.   JOURNAL OF CELL SCIENCE

Effects of kinesin-5 inhibition on dendritic architecture and microtubule organization

(2015) Olga I. Kahn et al.   MOLECULAR BIOLOGY OF THE CELL

Centrosomin represses dendrite branching by orienting microtubule nucleation

(2015) Cagri Yalgin et al.   NATURE NEUROSCIENCE

Building the Neuronal Microtubule Cytoskeleton

(2015) Lukas C. Kapitein et al.   NEURON

RAB-10 Regulates Dendritic Branching by Balancing Dendritic Transport

(2015) Caitlin A. Taylor et al.   PLoS Genetics

Nanoscopy of Filamentous Actin in Cortical Dendrites of a Living Mouse

(2014) Katrin I. Willig et al.   BIOPHYSICAL JOURNAL

Microtubule-severing protein Katanin regulates neuromuscular junction development and dendritic elaboration in Drosophila

(2014) C.-X. Mao et al.   DEVELOPMENT

γ-Tubulin controls neuronal microtubule polarity independently of Golgi outposts

(2014) Michelle M. Nguyen et al.   MOLECULAR BIOLOGY OF THE CELL

Microtubule Minus-End Binding Protein CAMSAP2 Controls Axon Specification and Dendrite Development

(2014) Kah Wai Yau et al.   NEURON

Actin Dynamics, Architecture, and Mechanics in Cell Motility

(2014) Laurent Blanchoin et al.   PHYSIOLOGICAL REVIEWS

PTRN-1, a microtubule minus end-binding CAMSAP homolog, promotes microtubule function in Caenorhabditis elegans neurons

(2014) Claire E Richardson et al.   eLife

Molecular mechanisms of dendrite stability

(2013) Anthony J. Koleske   NATURE REVIEWS NEUROSCIENCE

Fascin controls neuronal class-specific dendrite arbor morphology

(2012) J. Nagel et al.   DEVELOPMENT

Neocortical dendritic complexity is controlled during development by NOMA-GAP-dependent inhibition of Cdc42 and activation of cofilin

(2012) M. Rosario et al.   GENES & DEVELOPMENT

The Actin Nucleator Cobl Is Crucial for Purkinje Cell Development and Works in Close Conjunction with the F-Actin Binding Protein Abp1

(2012) N. Haag et al.   JOURNAL OF NEUROSCIENCE

Mitotic Motors Coregulate Microtubule Patterns in Axons and Dendrites

(2012) S. Lin et al.   JOURNAL OF NEUROSCIENCE

Katanin p60-like1 Promotes Microtubule Growth and Terminal Dendrite Stability in the Larval Class IV Sensory Neurons of Drosophila

(2012) A. Stewart et al.   JOURNAL OF NEUROSCIENCE

Development of dendrite polarity in Drosophila neurons

(2012) Sarah E Hill et al.   Neural Development

Golgi Outposts Shape Dendrite Morphology by Functioning as Sites of Acentrosomal Microtubule Nucleation in Neurons

(2012) Kassandra M. Ori-McKenney et al.   NEURON

Actin, Spectrin, and Associated Proteins Form a Periodic Cytoskeletal Structure in Axons

(2012) K. Xu et al.   SCIENCE

C. elegans bicd-1, homolog of the Drosophila dynein accessory factor Bicaudal D, regulates the branching of PVD sensory neuron dendrites

(2011) C. Aguirre-Chen et al.   DEVELOPMENT

CLIP-170 and IQGAP1 Cooperatively Regulate Dendrite Morphology

(2011) L. Swiech et al.   JOURNAL OF NEUROSCIENCE

The actin nucleation factor JMY is a negative regulator of neuritogenesis

(2011) Elif Nur Firat-Karalar et al.   MOLECULAR BIOLOGY OF THE CELL

UNC-33 (CRMP) and ankyrin organize microtubules and localize kinesin to polarize axon-dendrite sorting

(2011) Tapan A Maniar et al.   NATURE NEUROSCIENCE

New mechanisms and functions of actin nucleation

(2010) Elif Nur Firat-Karalar et al.   CURRENT OPINION IN CELL BIOLOGY

Time-lapse imaging and cell-specific expression profiling reveal dynamic branching and molecular determinants of a multi-dendritic nociceptor in C. elegans

(2010) Cody J. Smith et al.   DEVELOPMENTAL BIOLOGY

Branching out: mechanisms of dendritic arborization

(2010) Yuh-Nung Jan et al.   NATURE REVIEWS NEUROSCIENCE

The Growth Cone Cytoskeleton in Axon Outgrowth and Guidance

(2010) E. W. Dent et al.   Cold Spring Harbor Perspectives in Biology

F-BAR Proteins of the Syndapin Family Shape the Plasma Membrane and Are Crucial for Neuromorphogenesis

(2009) E. Dharmalingam et al.   JOURNAL OF NEUROSCIENCE

Molecular Architecture of Synaptic Actin Cytoskeleton in Hippocampal Neurons Reveals a Mechanism of Dendritic Spine Morphogenesis

(2009) Farida Korobova et al.   MOLECULAR BIOLOGY OF THE CELL

Unleashing formins to remodel the actin and microtubule cytoskeletons

(2009) Melissa A. Chesarone et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Microtubule assembly, organization and dynamics in axons and dendrites

(2009) Cecilia Conde et al.   NATURE REVIEWS NEUROSCIENCE

Drosophila IKK-related kinase Ik2 and Katanin p60-like 1 regulate dendrite pruning of sensory neuron during metamorphosis

(2009) H.-H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Slit and Robo regulate dendrite branching and elongation of space-filling neurons in Drosophila

(2008) Svetla Dimitrova et al.   DEVELOPMENTAL BIOLOGY

Microtubules Have Opposite Orientation in Axons and Dendrites of Drosophila Neurons

(2008) Michelle C. Stone et al.   MOLECULAR BIOLOGY OF THE CELL

Spatial control of branching within dendritic arbors by dynein-dependent transport of Rab5-endosomes

(2008) Daisuke Satoh et al.   NATURE CELL BIOLOGY

Dynein is required for polarized dendritic transport and uniform microtubule orientation in axons

(2008) Yi Zheng et al.   NATURE CELL BIOLOGY