Review
Oncology
Seyed-Abolfazl Hosseininasab-nodoushan, Kiarash Ghazvini, Tannaz Jamialahmadi, Masoud Keikha, Amirhossein Sahebkar
Summary: This study confirmed the clinical relevance of Chlamydia and Mycoplasma infection in the development of ovarian cancer risk, although the significance was marginal and study heterogeneity was significant. Further studies in this area are needed.
SEMINARS IN CANCER BIOLOGY
(2022)
Review
Chemistry, Medicinal
Masoud Keikha, Seyed-Abolfazl Hosseininasab-Nodoushan, Amirhossein Sahebkar
Summary: This study found that the prevalence of C. trachomatis infection in infertile males is 20.6%, and infection with C. trachomatis significantly increases the risk of male infertility.
MINI-REVIEWS IN MEDICINAL CHEMISTRY
(2023)
Review
Medicine, General & Internal
Ying Zuo, Ting-Ting Jiang, Yang Teng, Yan Han, Yue-Ping Yin, Xiang-Sheng Chen
Summary: This study examined the association between CT serology and fertility-related and pregnancy adverse outcomes. It found that CT-specific IgG was significantly associated with tubal factor infertility and ectopic pregnancy.
Review
Public, Environmental & Occupational Health
Anaanthan Bhuvanendran Pillai, Chin Mun Wong, Noor Dalila Inche Zainal Abidin, Sharifah Fazlinda Syed Nor, Mohd Fathulzhafran Mohamed Hanan, Siti Rasidah Abd Ghani, Nurul Afzan Aminuddin, Nazarudin Safian
Summary: This study reviewed meta-analysis studies on the prevalence of Chlamydia infection as a risk factor for developing cervical cancer. The results showed that Chlamydia trachomatis infection was significantly associated with the development of cervical cancer. Co-infection of Chlamydia trachomatis-HPV with cervical cancer is also plausible. However, future prospective cohort studies are needed to establish the temporal relationship between Chlamydia trachomatis-HPV and the development of cervical cancer.
IRANIAN JOURNAL OF PUBLIC HEALTH
(2022)
Article
Immunology
Laila Ferrera, Hanane Rogua, Nezha El Mansouri, Farid Kassidi, Mohamed Aksim, Abdallah El Farouqi, Said Chouham, Mohamed Nejmeddine
Summary: This study aims to assess the prevalence and possible risk factors of Chlamydia trachomatis (CT) and human papillomavirus (HPV)/CT co-infection in women from South of Morocco. The results showed that CT and HPV/CT co-infection were associated with an increased risk of developing cervical pathogenesis. Co-infection was also found to be associated with an increased risk of developing cervical abnormalities.
MICROBIAL PATHOGENESIS
(2023)
Review
Infectious Diseases
Liang-Fu Chen, Ting-Cheng Wang, Fu-Lun Chen, Shih-Chang Hsu, Chin-Wang Hsu, Chyi-Huey Bai, Yuan-Pin Hsu
Summary: This study compared the efficacy of doxycycline and azithromycin for the treatment of rectal chlamydia through systematic review and meta-analysis, finding that doxycycline had a significantly higher microbiological cure rate than azithromycin. The recommendation is made for developed countries to use doxycycline as a first-line treatment for rectal chlamydia. Further randomized controlled trials from developing countries are needed.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2021)
Article
Multidisciplinary Sciences
Brandie DePaoli Taylor, Ashley Hill, Maria J. Perez-Patron, Catherine L. Haggerty, Enrique F. Schisterman, Ashley Naimi, Akaninyene Noah, Camillia R. Comeaux
Summary: Hypertensive disorders of pregnancy (HDP) are associated with sexually transmitted infections, particularly Chlamydia and gonorrhea, which may increase the risk of severe preeclampsia.
SCIENTIFIC REPORTS
(2022)
Review
Biochemistry & Molecular Biology
Marisa Di Pietro, Simone Filardo, Ilaria Simonelli, Patrizio Pasqualetti, Rosa Sessa
Summary: This study conducted a systematic review and meta-analysis on the composition of the cervicovaginal microbiota in C. trachomatis infection. The results showed that the cervicovaginal microbiota in C. trachomatis-positive women was characterized by dominant Lactobacillus iners or a diverse mix of facultative or strict anaerobes.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Public, Environmental & Occupational Health
Ting Li, Zhaohui Liu, Dai Zhang, Qinping Liao, Shangrong Fan, Min Hao, Ying Hong, Xiufeng Huang, Huilan Wang, Zhengai Xiong, Hong Xu, Fengxia Xue, Min Xue, Xingsheng Yang, Jianqing Zhang
Summary: This study examined the prevalence of genital chlamydia and associated risk factors in Chinese female outpatients with genital tract infections. The results showed that the prevalence rate of chlamydia was 6.33% and the prevalence rate of gonococcal infection was 0.01%. Risk factors for chlamydia included premarital sex behavior, first sexual intercourse before the age of 20, and bacterial vaginosis.
FRONTIERS IN PUBLIC HEALTH
(2023)
Review
Oncology
Xingju Yang, Anam Siddique, Abdul Arif Khan, Qian Wang, Abdul Malik, Arif Tasleem Jan, Hassan Ahmed Rudayni, Anis Ahmad Chaudhary, Shahanavaj Khan
Summary: Pathogenic bacterial strains can alter cell function and induce inflammatory responses connected to the development of diseases. C. trachomatis is associated with cervical cancer, impacting DNA repair pathways and promoting oxidative DNA damage. Understanding these mechanisms can aid in the treatment and prevention of cervical cancer in C. trachomatis-infected patients.
Article
Biochemistry & Molecular Biology
Kanupriya Gupta, Howard W. Wiener, Hemant K. Tiwari, William M. Geisler
Summary: The study found that HLA DQB1*06 and DQB1*04 are associated with chlamydia reinfection, and this association is not influenced by other nearby HLA class II variants that are also associated with reinfection.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Stephan P. Verweij, Remco P. H. Peters, Arnold Catsburg, Henry J. C. de Vries, Sander Ouburg, Servaas A. Morre
Summary: This study aims to assess the potential association of MBL2 gene SNPs to Chlamydia trachomatis infection. The results showed clear associations between specific MBL2 genotypes, haplotypes, and different subgroups of C. trachomatis infection.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Immunology
Elizaveta Skarga, Heljae-Marja Surcel, Rudolf Kaaks, Tim Waterboer, Renee T. Fortner
Summary: Serologic markers of sexually transmitted infection history and EOC risk were evaluated. CT infection was not associated with EOC risk, while MG infection was positively associated with mucinous EOC risk.
JOURNAL OF INFECTIOUS DISEASES
(2023)
Article
Immunology
Xiaohong Su, Wenjing Le, Xiaofeng Zhu, Sai Li, Baoxi Wang, Guillermo Madico, Zhaoyan Yang, Christine E. Chaisson, Robert E. McLaughlin, Sumanth Gandra, Jungwon Yoon, Bo Zheng, Lisa A. Lewis, Sunita Gulati, George W. Reed, Sanjay Ram, Peter A. Rice
Summary: This study compared the exposure of female partners to male gonococcal burdens in infected versus uninfected partners. The findings showed that gonococcal infections in women were more frequent when their partners had higher burdens of infection. Additionally, co-infection with Chlamydia was also associated with increased gonococcal burdens in women.
JOURNAL OF INFECTIOUS DISEASES
(2022)
Review
Infectious Diseases
Margaret R. Hammerschlag, Roopali Sharma
Summary: Azithromycin is less effective than doxycycline in treating rectal infections, with further research needed to explore treatment options and dosages.
EXPERT REVIEW OF ANTI-INFECTIVE THERAPY
(2021)
Article
Obstetrics & Gynecology
Miaomiao Ye, Wenbin Huang, Fengyun Chen, Weinan Chen, Xueqiong Zhu
Summary: This study investigated the volume change of uterine leiomyomas during pregnancy and explored factors affecting their growth trends. The results showed that the growth rate of uterine leiomyomas was higher from the first to second trimester compared to the second to third trimester. Smaller leiomyomas were more likely to increase in size during pregnancy, and retroplacental leiomyomas were more likely to increase in volume compared to those located away from the placenta.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2023)
Editorial Material
Computer Science, Cybernetics
Haibin Zhu
Summary: In this issue, four articles are introduced, while the other three articles for the special section Next-Generation Networks for Industry 4.0 will be outlined in the special session editorial by guest editors Haisheng Yu, Jiehan Zhou, Zhixiong Chen, Yongzhi Wang, and Madhusanka Liyanage. They are highly appreciated for their effective work in collecting high-quality submissions.
IEEE SYSTEMS MAN AND CYBERNETICS MAGAZINE
(2023)
Article
Computer Science, Cybernetics
Qian Jiang, Haibin Zhu, Yan Qiao, Dongning Liu, Baoying Huang
Summary: This article introduces a method for group role assignment that considers cooperation and conflict factors to maximize team performance. It addresses two bottlenecks in practical applications and proposes a team evaluation method to help decision-makers establish sustainable teams. Large-scale simulation experiments demonstrate the feasibility and robustness of the proposed solution.
IEEE TRANSACTIONS ON COMPUTATIONAL SOCIAL SYSTEMS
(2023)
Article
Computer Science, Cybernetics
Peiyun Zhang, Xiaoqi Hua, Haibin Zhu
Summary: Blockchain as a ledger technology offers decentralization without the need for central servers. Cross-chain technology can connect different blockchains and enable interoperability and information sharing. This work designs a cross-chain digital asset system that includes two parallel chains and a relay chain. The proposed system ensures secure trading and payment through the transmission of cross-chain messages. Testing and analysis show that the system provides more secure trading and payment compared to its peers.
IEEE TRANSACTIONS ON COMPUTATIONAL SOCIAL SYSTEMS
(2023)
Article
Microbiology
Hai-Yan Zhu, Xu-Yang Wei, Xin-Zhan Liu, Feng-Yan Bai
Summary: A new yeast species belonging to the basidiomycetous yeast genus Cystofilobasidium was isolated from a marine sediment sample in Shandong province, China. Phylogenetic analysis based on gene sequences showed that this strain represents a novel species, named Cystofilobasidium josepaulonis sp. nov. This species differs from known species in the genus in terms of DNA sequence mismatches and teliospore germination behavior.
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
(2023)
Article
Automation & Control Systems
Haibin Zhu
Summary: This article establishes a new category of assignment problems by reviewing and extending the problems related to group role assignment. It specifies three new major assignment problems and proves a series of new related theorems. The article also provides a generalized formalization of this category of problems and emphasizes its importance in assignment research.
IEEE TRANSACTIONS ON SYSTEMS MAN CYBERNETICS-SYSTEMS
(2023)
Article
Oncology
Yanshan Jin, Shangdan Xie, Bo Sheng, Mei Chen, Xueqiong Zhu
Summary: This study aimed to explore the effect of propofol on the chemosensitivity of cervical cancer cells to paclitaxel. The results showed that propofol had no significant effect on the malignant behavior of the cells, but it enhanced the anti-cancer effect when used in combination with paclitaxel by reducing stathmin 1 expression.
Article
Oncology
Han Wang, Xin Chen, Yanshan Jin, Tingxian Liu, Yizuo Song, Xuejie Zhu, Xueqiong Zhu
Summary: This study aims to clarify the role and underlying molecular pathways of DYNLT3 in breast cancer tumorigenesis. Differential expression of DYNLT3 was detected in breast cancer tissues and cells, showing that DYNLT3 may act as a tumor-promoter in age-associated breast cancer. Knockdown of DYNLT3 suppressed cell growth, migration, and invasion, and induced cell apoptosis, highlighting its potential as a therapeutic target for breast cancer.
Article
Oncology
Xin Chen, Mengying Jiang, Shengjie Zhou, Hong Chen, Gendi Song, Yichen Wu, Xueqiong Zhu
Summary: Preferentially expressed antigen in melanoma (PRAME), a member of the CTA gene family, was found to be highly expressed in cervical cancer tissues and cells compared with control groups. PRAME promoted cell proliferation, migration, and invasion while reducing cell apoptosis and G0/G1 arrest by activating the Wnt/beta-catenin pathway. These findings may have implications for future cervical cancer treatments.
Article
Computer Science, Cybernetics
Haibin Zhu
Summary: This article presents a model for simulating resource/benefit distribution and checks for Pareto improvements using a revised GRA model. The study shows that Pareto improvements are not possible when resources are insufficient, and can only be achieved when there are sufficient resources and manpower.
IEEE TRANSACTIONS ON COMPUTATIONAL SOCIAL SYSTEMS
(2023)
Article
Engineering, Biomedical
Shuya Pan, Zhengwei Sun, Bo Zhao, Liqing Miao, Qingfeng Zhou, Tianfeng Chen, Xueqiong Zhu
Summary: This review focuses on the application of Mn-based nanomaterials in radiotherapy. These nanomaterials can enhance the efficacy of radiotherapy by alleviating tumor hypoxia, increasing reactive oxygen species production, increasing GSH conversion, and promoting antitumor immunity. Furthermore, they can also serve as contrast agents for precision therapy.
Article
Oncology
Bo Sheng, Bo Zhao, Yue Dong, Jiamin Zhang, Suni Wu, Huihui Ji, Xueqiong Zhu
Summary: This study investigated the expression and function of CPNE1 in ovarian cancer. The results showed that CPNE1 overexpression was associated with poor prognosis in ovarian cancer and promoted tumor cell proliferation, invasion, and migration. Furthermore, CPNE1 was found to mediate M2 macrophage polarization and upregulate CD163, CD206, and interleukin-10, suggesting a potential therapeutic target for ovarian cancer.
Article
Cell Biology
Yi Liu, Hejing Liu, Miaomiao Ye, Mengying Jiang, Xin Chen, Gendi Song, Huihui Ji, Zhi-wei Wang, Xueqiong Zhu
Summary: This study reveals that BRD4, a member of the BET protein family, is asymmetrically methylated by PRMT1 in ovarian cancer. The overexpression of PRMT1 is associated with poor prognosis in ovarian cancer patients. Silencing PRMT1 inhibits ovarian cancer proliferation, migration, and invasion. PRMT1-mediated BRD4 methylation promotes BRD4 phosphorylation and is involved in ovarian cancer metastasis.
CELL DEATH & DISEASE
(2023)
Article
Oncology
Miaomiao Ye, Tingxian Liu, Liqing Miao, Shuangwei Zou, Huihui Ji, Jian'an Zhang, Xueqiong Zhu
Summary: Zinc finger protein 275 (ZNF275) has been found to be highly expressed in cervical cancer tissues and downregulation of ZNF275 can inhibit tumor growth and weaken the AKT/Bcl-2 signaling pathway. Additionally, the AKT inhibitor triciribine synergizes with cisplatin to enhance the therapeutic effect on cervical cancer cells expressing high ZNF275. The combination treatment of triciribine and cisplatin is more effective in inducing tumor regression than single agents in cervical cancer PDX models expressing high ZNF275.
Review
Cell & Tissue Engineering
Yizuo Song, Hejing Liu, Shuya Pan, Xinli Xiang, Miaomiao Ye, Xueqiong Zhu
Summary: Mesenchymal stromal cells (MSCs) have shown great promise in various fields such as regenerative medicine and cancer therapy. However, their role as important components within the tumor microenvironment poses potential tumorigenic risks, hindering their clinical translation.
STEM CELL RESEARCH & THERAPY
(2023)