Article
Food Science & Technology
Jon Jyoti Kalita, Pragya Sharma, Utpal Bora
Summary: Food safety is a crucial concern due to the presence of contaminants that can have harmful effects on food. Oligonucleotide aptamers have emerged as a promising alternative to antibodies in the analysis of food contaminants, and various design strategies have led to disruptive innovations in this field.
Article
Chemistry, Analytical
Zhijuan Duan, Liuxi Tan, Ruilin Duan, Mengxi Chen, Fan Xia, Fujian Huang
Summary: In this study, a photoresponsive DNA probe was introduced for ATP detection in single living cells, with two different methods discussed for probe activation. The developed biosensor enables dictated dual-model ATP detection with high spatiotemporal resolution in single living cells during different cell cycles.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Kun Chen, Guangrong Zou, Wei Xiong, Zhiyong He, Shen Yan, Shanshan Qin, Qi Wang, Hengjiang Cong, Chun-Jiang Wang, Xiang Zhou
Summary: The study introduces a novel method combining aptamer binding and catalytic reactions to regulate drug release under pathological conditions, reducing drug toxicity and showing great potential for application in cancer treatment.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Nanoscience & Nanotechnology
Erika Nasu, Norifumi Kawakami, Kenji Miyamoto
Summary: Chemical modification of protein nanocages holds promise for various applications, but dual-surface modification using different chemicals remains challenging. Surface pores on artificial protein nanocage TIP60 function as size-dependent molecular filters, allowing only small molecules to pass through. Dual-surface functionalization of TIP60 enables it to release internal small molecules in a redox-responsive manner, making it a useful nanocarrier for drug delivery and molecular filtration systems.
ACS APPLIED NANO MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Elisa Poyatos-Racionero, Edgar Perez-Esteve, Serena Medaglia, Elena Aznar, Jose M. Barat, Ramon Martinez-Manez, Maria Dolores Marcos, Andrea Bernardos
Summary: Clay minerals with low toxicity and high adsorption capacities are attractive for controlled delivery applications. In this study, organonanoclays loaded with rhodamine B dye and functionalized with oleic acid were successfully developed for active and controlled payload-release. The organonanoclays effectively confined the entrapped cargos in an aqueous environment and released them in the presence of surfactants. Furthermore, in vitro cell viability assays demonstrated the biocompatibility of the organonanoclays.
Review
Food Science & Technology
Yan Feng, Shuangdi Chen, Zhaofeng Li, Zhengbiao Gu, Shude Xu, Xiaofeng Ban, Yan Hong, Li Cheng, Caiming Li
Summary: This review systematically introduces the principles and applications of cyclodextrin-based controlled release systems, including CD inclusion complexes, CD coupling, supramolecular hydrogels, and supramolecular micelles. These controlled release systems have specific applications in areas such as food, medicine, cosmetics, textiles, agriculture, environmental protection, and chemical materials.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Spectroscopy
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Wenhao Ma, Tingxiu Xiang, Changjun Hou, Danqun Huo
Summary: A label-free fluorescent aptamer sensor based on zeolite imidazolic acid framework-8 was developed for the detection of HER2 levels in breast cancer patients. The sensor showed good detection performance, sensitivity, and low background interference, making it a potential tool for the clinical diagnosis and monitoring of breast cancer.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Review
Chemistry, Multidisciplinary
Ping Huang, Daizheng Lian, Hualin Ma, Nansha Gao, Limin Zhao, Ping Luan, Xiaowei Zeng
Summary: Mesoporous silica nanoparticles, with their simple synthesis, biocompatibility, and high surface area, have been developed as drug carriers for targeted and controlled drug release. By designing gated systems using various materials, these nanoparticles offer a new approach for selective delivery of antitumor drugs. Challenges and future prospects of gated mesoporous silica nanoparticles are discussed for their potential in drug delivery systems.
CHINESE CHEMICAL LETTERS
(2021)
Article
Chemistry, Multidisciplinary
M. Rahim, M. R. H. Mas Haris
Summary: A green biocomposite was prepared with chitosan dispersed in partially cross-linked natural rubber matrices. Chitosan was well dispersed in the matrices, indicating successful stabilization of natural rubber latex by sodium dodecyl sulfate. The biocomposites showed good swelling properties and were used for controlled release of urea.
MATERIALS TODAY CHEMISTRY
(2021)
Article
Nanoscience & Nanotechnology
Jialang Zhuang, Siqi Chen, Ye Hu, Fan Yang, Qin Huo, Ni Xie
Summary: The study developed tumor-targeted and redox-responsive mesoporous silica nanoparticles (MSNs) for the co-delivery of Doxorubicin and siTIE2 to improve the treatment of metastatic breast cancer. The controlled release of drugs within cells was achieved through redox-sensitive disulfide bonds, resulting in enhanced therapeutic effects in vitro and in vivo, including lower IC50 values and improved anti-tumor and anti-metastatic effects.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2021)
Article
Chemistry, Analytical
Jeong Ah Park, Eunhae Park, Yein Kwon, Wonhwa Lee, June Hong Ahn, Tae-Hyung Kim, Moonbong Jang, Junhong Min, Younghun Kim, Taek Lee
Summary: The researchers constructed a pre-treatment-free electrochemical biosensor for rapid detection of MMP-9 in clinical samples. They utilized Au@BNNTs to enhance the sensor's performance and successfully achieved detection of MMP-9. The electrochemical signal amplification ability of Au@BNNTs was confirmed, demonstrating the potential of the biosensor for MMP-9 detection in clinical samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Nanoscience & Nanotechnology
Fei Pan, Altangerel Amarjargal, Stefanie Altenried, Mengdi Liu, Flavia Zuber, Zhihui Zeng, Rene M. Rossi, Katharina Maniura-Weber, Qun Ren
Summary: By adjusting the T-g of polymer blends, controlled release of octenidine at 37 degrees C was achieved, and the nanofibrous membranes exhibited distinct antibacterial activity against Gram negative and positive pathogens at this temperature.
ACS APPLIED BIO MATERIALS
(2021)
Article
Agronomy
Quan Ma, Mengyao Wang, Guoli Zheng, Yuan Yao, Rongrong Tao, Min Zhu, Jinfeng Ding, Chunyan Li, Wenshan Guo, Xinkai Zhu
Summary: Twice application of controlled-release nitrogen fertilizer can improve wheat yield and nitrogen use efficiency by synchronizing nitrogen release with wheat’s demand, delaying leaf senescence, and increasing yield.
FIELD CROPS RESEARCH
(2021)
Article
Polymer Science
Wenqian Zhu, Yanping Zhao, Zhiming Wu, Fengzhu Lv, Yihe Zhang, Sufang Guo
Summary: This article presents a composite hydrogel preparation method for designing and preparing smart drug release systems in the field of medicine. The hydrogel exhibits strong mechanical properties, biocompatibility, and controlled drug release, making it suitable for application as a skin patch.
Review
Chemistry, Multidisciplinary
Hao Lu, Canping Dun, Hiral Jariwala, Rui Wang, Peiyuan Cui, Haipeng Zhang, Qigen Dai, Shuo Yang, Hongcheng Zhang
Summary: This review article focuses on the application and progress of environmentally friendly bio-based materials in the polyurethane-coated controlled-release fertilizer industry. Using animal and plant oils, starch, lignin, and cellulose as raw materials, polyols can be produced to replace petroleum-based materials and prepare polyurethane film coating for controlled-release fertilizers. The research on bio-based polyurethane has revealed its great potential in the production and application of coated controlled-release fertilizers.
JOURNAL OF CONTROLLED RELEASE
(2022)
Article
Chemistry, Analytical
Xiqin Yang, Min Chen, Zhanhua Zhang, Yang Li, Peipei Wang, Xiliang Luo, Shaoping Lv
Summary: This study proposes an effective strategy to construct low fouling electrochemical biosensors based on specially designed Aib-peptides. These Aib-peptides exhibit excellent antifouling properties and enhanced stability, enabling accurate and reliable detection of IgG in clinical human sera.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Analytical
Xuanhao Zhang, Qian Li, Qiqi Chao, Yuxi Zhang, Xufeng Sun, Gao-Chao Fan, Zhi Ling Song, Rongmei Kong, Xiliang Luo
Summary: In this study, a protein enzyme-free and general approach for sensitive detection of single nucleotide polymorphisms (SNPs) is developed using asymmetric MNAzyme probes. The multi-arm probe (MNAzyme-9M-13) with two asymmetric recognition arms is designed to detect EGFR T790 M mutation. Through a one-pot mixing, the probe enables the sensitive detection of the mutation without protein enzyme or multi-step operation. The strategy also shows potential for SNPs detection in long genomic sequences and short microRNAs.
ANALYTICA CHIMICA ACTA
(2023)
Article
Materials Science, Multidisciplinary
Nianzu Liu, Yihui Ma, Zhenying Xu, Yingshu Guo, Xiliang Luo
Summary: We report a PANI-HA hydrogel that combines rigid conducting polymer with flexible HA. The supramolecular assembly of PANI and HA via boronic acid bonds yields PANI-HA hydrogel with unique microstructure, electrical conductivity and hydrophilicity, showing excellent supercapacitor performance and electrochemical sensing for IgG. The PANI-HA hydrogel-based electrode exhibits high specific capacitance (369 F g(-1)) and good cycling stability (85% capacity retention after 1000 charge-discharge cycles). It can also be used as an electrochemical biosensor for IgG detection with good sensitivity, wide detection range, and low detection limit.
JOURNAL OF MATERIALS SCIENCE
(2023)
Editorial Material
Chemistry, Analytical
Xiliang Luo
Article
Chemistry, Multidisciplinary
Sai Zhang, Ping Chen, Yu Fan, Yan Zhao, Wenlong Yang, Hongtao Gao, Xiliang Luo
Summary: This study successfully synthesized amorphous and crystalline NiS2 nanospheres using a simple method and found that the amorphous structure of NiS2 catalyst has superior electrochemical activity for methanol oxidation reaction compared to the crystalline counterpart.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Lei Zhang, Han Liu, Qianyao Du, Guoqiang Zhang, Shanhui Zhu, Zhongtao Wu, Xiliang Luo
Summary: Photoresponsive phase change materials have the ability to store and release both photon and heat energy. By designing azobenzene surfactants at the molecular level, it is possible to achieve high gravimetric energy density and enhance molar isomerization enthalpy.
Article
Chemistry, Analytical
Xiqin Yang, Ping Chen, Xi Zhang, Hao Zhou, Zhen Song, Wenlong Yang, Xiliang Luo
Summary: A simple tactic for electrochemical determination of HER2, a typical biomarker for breast cancer, was developed through the construction of a low fouling sensing interface functionalized with PEG and peptide. The biosensor exhibited strong antifouling performances in complex biofluids due to the combined effect of PEG and peptide, and it had an ultralow limit of detection and a wide linear range for HER2 assay. The combination of PEG and peptide provided an effective strategy for the development of low fouling sensing platforms in complex biotic environments.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Analytical
Tingting Zhao, Jiaheng Shi, Junhao Wang, Yanyun Cui, Yifan Yang, Shenghao Xu, Xiliang Luo
Summary: Developing an endogenous stimuli-responsive and ultrasensitive DNA sensing platform that contains a logic gate biocomputation for precise cell subtype identification holds great potential for disease diagnosis and prognostic estimation.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Shuju Zhao, Zhen Song, Tao Liu, Xin Wang, Yanxin Li, Yaqun Xu, Hao Wang, Yumin Wu, Xiliang Luo
Summary: Zwitterionic peptides with strong water binding ability have been designed to construct antifouling biosensors with enhanced stability in complex biological fluids. The designed peptides demonstrated much stronger antifouling capability and significantly enhanced stability in human serum and blood. Furthermore, the biosensor integrating the designed antifouling peptide with CEA aptamer exhibited a great sensitivity for detecting CEA protein, making it promising for practical applications.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Physical
Nianzu Liu, Ruoxing Wang, Shengjie Gao, Ruifang Zhang, Fengru Fan, Yihui Ma, Xiliang Luo, Dong Ding, Wenzhuo Wu
Summary: Leveraging mechanically-induced piezoelectric polarization, piezocatalysis emerges as a viable mechanism for enhancing catalytic processes. Nanostructured, catalytically active, rationally designed piezo-electric semiconductors can achieve high-performance catalysts for various applications using cost-effective electrocatalytic pathways, such as mechanical stimuli. The facile synthesis of high-quality ZnO nanostructures enables low-cost, scalable manufacture and direct integration into electrocatalysts for enhanced performance.
Article
Chemistry, Analytical
Yaqun Xu, Xiujuan Qiao, Zhi-Ling Song, Gao-Chao Fan, Xiliang Luo
Summary: A robust photoelectrochemical (PEC) biosensor capable of accurate detection in human serum was developed by integrating a new engineered branching peptide (EBP) into a synergetic dual-photoelectrode system. The biosensor exhibited high sensitivity, specificity, and anti-interference properties.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Fu-Hui Lyu, Chen-Chen Li, Yue Li, Lin Cui, Xi-Liang Luo
Summary: Metal-organic gels (MOGs) are gel materials formed by bridging metal ions and organic ligands via non covalent interactions. They have advantages such as easy preparation, large specific surface area, tunable structure, and abundant metal sites, making them widely used in sensing, analysis, catalysis, adsorption, energy storage and electrochromic devices. This paper reviews the progress in the research and application of MOGs in these fields, and discusses the challenges, future trends and application prospects.
CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Tingting Zhao, Jiaheng Shi, Junhao Wang, Yanyun Cui, Yifan Yang, Shenghao Xu, Xiliang Luo
Summary: A DNA sensing platform with endogenous stimuli-responsive and ultrasensitive characteristics, incorporating a logic gate biocomputation, has been developed for precise cell subtype identification in disease diagnosis and prognostic estimation.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Rui Han, Wenjie Hou, Yang Li, Min Chen, Caifeng Ding, Xiliang Luo
Summary: A sensitive electrochemical biosensor based on a self-designed cyclic peptide is capable of detecting the RBD antigen in human blood. The cyclic peptide possesses excellent antifouling properties and strong anti-enzymatic hydrolysis ability, making the biosensor stable and reliable for COVID-19 antigen testing.
SENSORS & DIAGNOSTICS
(2023)
Article
Biophysics
Ze Hu, Hao Wang, Huimin Chen, Gao-Chao Fan, Xiliang Luo
Summary: In this study, an ingenious approach of target-triggered cascade signal amplification in porous anodic aluminum oxide nanochannels was developed for ultrasensitive photoelectrochemical DNA bioanalysis. The innovative nanochannels PEC strategy launched a novel detecting platform for trace levels of DNA, providing a potential inspiration for other smart nanochannels PEC bioassays.
BIOSENSORS & BIOELECTRONICS
(2023)
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)
