Safety, Pharmacokinetics, and Pharmacodynamics of SHR7280, a Non-peptide GnRH Antagonist in Premenopausal Women with Endometriosis: A Randomized, Double-Blind, Placebo-Controlled Phase 1 Study

Once daily oral relugolix combination therapy versus placebo in patients with endometriosis-associated pain: two replicate phase 3, randomised, double-blind, studies (SPIRIT 1 and 2)

(2022) Linda C Giudice et al.   LANCET

Safety, pharmacokinetics, and pharmacodynamics of SHR7280, an oral gonadotropin-releasing hormone antagonist in healthy premenopausal women

(2022) Yi Xu et al.   Frontiers in Pharmacology

Endometriosis

(2020) Krina T. Zondervan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Relugolix, an oral gonadotropin-releasing hormone receptor antagonist, reduces endometriosis-associated pain in a dose–response manner: a randomized, double-blind, placebo-controlled study

(2020) Yutaka Osuga et al.   FERTILITY AND STERILITY

Population Pharmacokinetics of Elagolix in Healthy Women and Women with Endometriosis

(2018) Insa Winzenborg et al.   CLINICAL PHARMACOKINETICS

Long-Term Outcomes of Elagolix in Women With Endometriosis

(2018) Eric Surrey et al.   OBSTETRICS AND GYNECOLOGY

Design and Conduct Considerations for First-in-Human Trials

(2018) Jie Shen et al.   CTS-Clinical and Translational Science

Choosing the right surgical technique for deep endometriosis: shaving, disc excision, or bowel resection?

(2017) Olivier Donnez et al.   FERTILITY AND STERILITY

Dose-Dependent Suppression of Gonadotropins and Ovarian Hormones by Elagolix in Healthy Premenopausal Women

(2017) Juki Ng et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Treatment of Endometriosis-Associated Pain with Elagolix, an Oral GnRH Antagonist

(2017) Hugh S. Taylor et al.   NEW ENGLAND JOURNAL OF MEDICINE

The direct and indirect costs associated with endometriosis: a systematic literature review

(2016) Ahmed M. Soliman et al.   HUMAN REPRODUCTION

Prevention of the recurrence of symptom and lesions after conservative surgery for endometriosis

(2015) Kaori Koga et al.   FERTILITY AND STERILITY

ESHRE guideline: management of women with endometriosis

(2014) G. A. J. Dunselman et al.   HUMAN REPRODUCTION

Consensus on current management of endometriosis

(2013) Neil P. Johnson et al.   HUMAN REPRODUCTION

Elagolix Treatment for Endometriosis-Associated Pain

(2013) Michael P. Diamond et al.   Reproductive Sciences

Pathogenesis and pathophysiology of endometriosis

(2012) Richard O. Burney et al.   FERTILITY AND STERILITY

The burden of endometriosis: costs and quality of life of women with endometriosis and treated in referral centres

(2012) S. Simoens et al.   HUMAN REPRODUCTION

Impact of endometriosis on quality of life and work productivity: a multicenter study across ten countries

(2011) Kelechi E. Nnoaham et al.   FERTILITY AND STERILITY

Endometriosis

(2010) Linda C. Giudice   NEW ENGLAND JOURNAL OF MEDICINE

Endometriosis

(2009) Serdar E. Bulun   NEW ENGLAND JOURNAL OF MEDICINE

Suppression of Gonadotropins and Estradiol in Premenopausal Women by Oral Administration of the Nonpeptide Gonadotropin-Releasing Hormone Antagonist Elagolix

(2008) R. Scott Struthers et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Non-Peptide Gonadotropin-Releasing Hormone Receptor Antagonists

(2008) Stephen F. Betz et al.   JOURNAL OF MEDICINAL CHEMISTRY