Editorial Material
Medicine, General & Internal
Nora Eberfalvi Lipositsne, Kirsten Bouchelouche
Summary: We present a case of a 69-year-old female with prolonged fever who underwent 18F-FDG PET/CT. The scan revealed subcutaneous nodules with increased 18F-FDG uptake on the thorax and upper extremities, as well as bilateral lung infiltrates due to organizing pneumonitis. Clinical examination confirmed erythema nodosum induced by COVID-19 infection. Prednisone treatment resulted in improvement of the erythema nodosum. This is the first report of COVID-19-induced erythema nodosum diagnosed on 18F-FDG PET/CT.
Article
Emergency Medicine
Nicole Sipfle, Rachel E. Bridwell, Jamie Roper
Summary: COVID-19, a viral disease first discovered in Wuhan, China, has rapidly become a global pandemic with various dermatologic manifestations. Early identification and treatment of novel presentations of the virus are crucial for preventing complications.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Review
Pediatrics
Sandra Trapani, Chiara Rubino, Lorenzo Lodi, Massimo Resti, Giuseppe Indolfi
Summary: Erythema nodosum (EN) is a common form of panniculitis in children. It can be primary or secondary, with secondary cases associated with various conditions. The diagnosis is clinical, and basic work-up and further investigations should be performed based on the medical history and associated manifestations. EN has a favorable prognosis, and treatment should target the underlying condition if necessary.
Article
Dermatology
Kang Su Kim, Jae Seok Kim, Sang Seok Kim, Chul Woo Kim
Summary: Erythema nodosum and erythema induratum of Bazin are inflammatory diseases of the lower extremities that are clinically distinguishable but can overlap. Both diseases are reported to be related to Mycobacterium tuberculosis infection, and this study aimed to improve the detection rate of M. tuberculosis in skin lesions using a new nested polymerase chain reaction targeting the IS6110 sequence. The study found that testing for tuberculosis in patients with multiple tender subcutaneous nodules on their lower extremities is important in high-burden tuberculosis countries like Korea.
INDIAN JOURNAL OF DERMATOLOGY VENEREOLOGY & LEPROLOGY
(2022)
Article
Pediatrics
Sarah Abu-Rumeileh, Federica Barbati, Giuseppe Indolfi, Sandra Trapani
Summary: This study retrospectively investigated children diagnosed with erythema nodosum in the pediatric emergency room of Meyer Children's University Hospital in Florence, Italy over a 12-year period. The study aimed to evaluate the epidemiology, clinical manifestations, etiology, treatment, and course of the disease in children. A total of 68 patients were included, with 55.9% having a definite etiologic diagnosis and the rest classified as idiopathic.
EUROPEAN JOURNAL OF PEDIATRICS
(2023)
Article
Infectious Diseases
Norah Anthony, Sebastien Duquenne, Nael Zemali, Aurelie Foucher, Nicolas Dupin, Antoine Bertolotti
Summary: This article reports a case of erythema nodosum (EN) with a rare etiology of syphilis. The patient presented with a maculopapular rash and a hypodermic lesion, which were further investigated and ruled out other possible causes. The diagnosis of syphilis was made based on positive results and recovery after treatment. It is important to consider EN as a rare manifestation of syphilis, especially in the context of increasing cases among men who have sex with men in mainland France and heterosexuals on Reunion Island.
INFECTION AND DRUG RESISTANCE
(2022)
Article
Medicine, General & Internal
Gustavo U. Machado, Thiago Amparo, Flavia Bulhoes, Paulo R. L. Machado
Summary: This article describes four cases of leprosy patients with chronic recalcitrant erythema nodosum leprosum (ENL) treated with cyclophosphamide pulse therapy. The pulse therapy resulted in partial or complete regression of symptoms and allowed for a reduction in medication dosage, effectively controlling the disease.
FRONTIERS IN MEDICINE
(2023)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Selin Kesim, Salih Ozguven, Tunc Ones, Halil Turgut Turoglu, Tanju Yusuf Erdil
Summary: Behcet disease is a rare multisystemic vasculitis that can affect all sizes and types of blood vessels. The most common skin lesions of Behcet disease are recurrent painful erythematous nodular lesions called erythema nodosum. Here, we present F-18-FDG PET/CT images of erythema nodosum lesions in a patient with Behcet disease.
CLINICAL NUCLEAR MEDICINE
(2021)
Article
Medicine, General & Internal
Sujing Li, Bingzhou Ji, Yan Teng, Hui Tang, Hong Cui, Xiaohua Tao, Yibin Fan, Youming Huang
Summary: This article reports a Chinese patient possibly with erythema nodosum-like exanthema secondary to nocardiosis. The diagnosis was based on clinical presentation, histopathological evidence, and microbiological findings. Reports on new presentations of Nocardia are important for early identification and treatment.
MEDICINA-LITHUANIA
(2022)
Article
Medicine, General & Internal
Tsutomu Takeda, Daisuke Asaoka, Sakiko Ogiya, Ken Akashi, Daiki Abe, Maiko Suzuki, Yoichi Akazawa, Kumiko Ueda, Hiroya Ueyama, Tomoyoshi Shibuya, Taro Osada, Mariko Hojo, Shu Hirai, Rie Ueki, Akihito Nagahara
Summary: We present a rare case of Yersinia enterocolitica enteritis with initial symptoms of fever and abdominal pain followed by erythema nodosum. The diagnosis was confirmed through colonoscopy, computed tomography, pathology, and mucosal culture. Yersinia enteritis can be cured with proper diagnosis and treatment. Erythema nodosum, although uncommon, should still be considered as a possible differential diagnosis.
Review
Rheumatology
Sarah Ringsted, Marcia Friedman
Summary: IGM is a mysterious inflammatory breast disorder that responds well to immunomodulatory treatment with methotrexate. Patients treated with methotrexate have the highest rates of relapse-free remission compared to those treated with steroids alone or steroids and surgery. Erythema nodosum and arthritis/arthralgia may be under-recognized manifestations of IGM when managed outside rheumatology settings.
INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES
(2021)
Article
Immunology
Jie Pu, Valerie Miranda, Devin Minior, Shane Reynolds, Benjamin Rayhorn, Katherine D. Ellingson, John N. Galgiani
Summary: The objective of this study was to improve testing rates for coccidioidomycosis (CM) in patients with pneumonia (PNA) in urgent care clinics. Analysis of medical records showed that although there was an increase in testing rates, over three quarters of pneumonia patients still did not receive CM testing.
OPEN FORUM INFECTIOUS DISEASES
(2023)
Article
Oncology
Elham Nasrollahi, Alessio Giubellino, Armin Rashidi
Summary: This article reports a rare case of treatment-related erythema nodosum (EN) in a patient with acute myeloid leukemia (AML), which was treated with topical and oral steroids. The focus of the discussion is on considering EN as an alternative diagnosis when determining the correct diagnosis.
JOURNAL OF ONCOLOGY PHARMACY PRACTICE
(2023)
Review
Rheumatology
Konstantinos Parperis, Savvas Achilleos, Egli Costi, Michail Vardas
Summary: Granulomatous mastitis (GM) is a rare inflammatory breast condition often associated with erythema nodosum and arthritis. Among 29 patients, mostly females, unilateral breast involvement was common, and treatment with glucocorticoids showed positive results in symptom improvement.
RHEUMATOLOGY INTERNATIONAL
(2021)
Article
Rheumatology
Ivan Perez Haded, Juan Sebastian Bayona D'vera, Andrea Sofia Blanco Espinoza, Bruny Carolina Llamas Castellanos, Mariam Carolina Rolon Cadena
Summary: This is an unusual case of erythema nodosum (EN) associated with the administration of zoledronic acid (ZA) and denosumab, with incidental histopathological findings of calciphylaxis.
INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES
(2022)
