Article
Medicine, Research & Experimental
Kun-Tai Kang, Shuenn-Nan Chiu, Wen-Chin Weng, Pei-Lin Lee, Wei-Chung Hsu
Summary: This study found that children with obstructive sleep apnea (OSA) had significantly increased blood pressure and blood pressure variability. Compared to those with primary snoring, children with severe OSA showed higher nighttime blood pressure levels and variability.
Article
Medicine, General & Internal
Baran Balcan, Yeliz Celik, Jennifer Newitt, Patrick J. Strollo, Yuksel Peker
Summary: This study found that female sex and BMI were related to REM-predominant OSA in a cohort of patients with coronary artery disease. In the multivariate model, MCS was inversely associated with REM-AHI.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Clinical Neurology
Sofia F. Furlan, Viktor Sinkunas, Lucas P. Damiani, Ronaldo B. Santos, Matheus Peres, Pedro A. Lemos, Chi-Hang Lee, Geraldo Lorenzi-Filho, Luciano F. Drager
Summary: This study aimed to explore the associations of obstructive sleep apnea (OSA) and sleep duration (SD) with renal function in subjects with coronary artery disease (CAD). The results showed that OSA severity and SD were not independently associated with chronic kidney disease (CKD) in CAD patients.
Article
Health Care Sciences & Services
Geetha Kandasamy, Tahani Almeleebia
Summary: This study aimed to assess OSA and the relationship between AHI and polysomnographic characteristics in OSA patients. The results showed a significant prevalence of obesity and high frequency of OSA in men, with polysomnography being the primary method for early detection and treatment of the condition.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Clinical Neurology
Juan Hernando del Portillo, Boris Miguel Hernandez, Maria Angelica Bazurto, Dario Echeverri, Jaime Cabrales
Summary: The frequency of coronary artery ectasia (CAE) is higher in patients with obstructive sleep apnea (OSA) compared to the general population. However, the severity of OSA is not directly related to the severity of CAE.
JOURNAL OF CLINICAL SLEEP MEDICINE
(2022)
Article
Critical Care Medicine
Ali Azarbarzin, Andrey Zinchuk, Andrew Wellman, Gonzalo Labarca, Daniel Vena, Laura Gell, Ludovico Messineo, David P. White, Daniel J. Gottlieb, Susan Redline, Yuksel Peker, Scott A. Sands
Summary: In this post hoc analysis, it was found that patients with higher Delta HR experience greater cardiovascular benefits from CPAP therapy, while those with lower Delta HR do not have significant risk reduction.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2022)
Article
Medicine, General & Internal
Yuksel Peker, Henrik Holtstrand-Hjalm, Yeliz Celik, Helena Glantz, Erik Thunstrom
Summary: Postoperative atrial fibrillation (POAF) is common in patients with coronary artery disease (CAD) after coronary artery bypass grafting (CABG). This study found that severe obstructive sleep apnea (OSA) is significantly associated with POAF in CAD patients undergoing CABG.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Physiology
Pierre Labeix, Mathieu Berger, Amandine Zellag, Arnauld Garcin, Jean-Claude Barthelemy, Frederic Roche, David Hupin
Summary: This study found that specific inspiratory muscle training (IMT) can significantly reduce the severity of obstructive sleep apnea (OSA) in patients with coronary artery disease (CAD). However, there was no significant improvement in AHI in the IMT group compared to the control group.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Health Care Sciences & Services
Jui-Kun Chiang, Yen-Chang Lin, Yee-Hsin Kao
Summary: The study found that for patients with OSA, there was an increase in the value of RMSSD and a decrease in the LF/HF ratio during the first hour of sleep. An elevated LF/HF ratio during snoring was associated with the first snoring episode occurring more than 20 minutes after lying down to sleep (OR = 10.9, p = 0.004) and with patients diagnosed with severe OSA (OR = 5.01, p = 0.045).
Article
Medicine, General & Internal
Alberto Alonso-Fernandez, Caterina Ribot Quetglas, Andrea Herranz Mochales, Ainhoa Alvarez Ruiz De Larrinaga, Andres Sanchez Baron, Paula Rodriguez Rodriguez, Ana Victoria Gil Gomez, Carla Pia Martinez, Jose Pablo Cubero Marin, Maria Barcelo Nicolau, Maria Cerda Moncadas, Mercedes Codina Marcet, Monica De La Pena Bravo, Antonia Barcelo Bennasar, Amanda Iglesias Coma, Daniel Morell-Garcia, Jose Antonio Pena Zarza, Maria Paloma Gimenez Carrero, Joaquin Duran Cantolla, Jose Maria Marin Trigo, Maria Concepcion Pinas Cebrian, Joan B. Soriano, Francisco Garcia-Rio
Summary: The study revealed that obstructive sleep apnea in normal pregnancy is associated with higher systemic inflammation levels, particularly related to obstructive events, especially during REM sleep. Moreover, systemic inflammation was found to be inversely correlated with neonatal birth weight and gestational age.
FRONTIERS IN MEDICINE
(2021)
Article
Biology
Roni Meidan, Ofir Elalouf, Riva Tauman, Victoria Furer, Ari Polachek, Jonathan Wollman, Tali Eviatar, Michael Zisapel, David Levartovsky, Estelle Seyman, Ori Elkayam, Daphna Paran
Summary: Marked fatigue is common in patients with systemic lupus erythematosus (SLE). This study aimed to assess the association of sleep disorders, including obstructive sleep apnea (OSA), with SLE. The results showed that SLE patients had an increased prevalence of OSA and poorer quality of sleep compared to healthy controls. The findings suggest that active disease and accumulated damage may be associated with OSA, highlighting the importance of identifying OSA in patients with SLE.
Review
Cardiac & Cardiovascular Systems
Eng Lee Ooi, Sharmalar Rajendran
Summary: Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder characterized by airway obstruction during sleep, leading to breathing pauses and reduced oxygen levels. OSA patients often experience poor sleep quality and decreased quality of life. OSA is linked to both structural and functional coronary artery disease (CAD), caused by atherosclerosis and coronary vasomotor disorders respectively. Intermittent hypoxia (IH) and other factors play a significant role in the development of atherogenesis in OSA. While CPAP therapy has been associated with a decrease in cardiovascular events, randomized controlled trials have not shown its significance.
CURRENT PROBLEMS IN CARDIOLOGY
(2023)
Article
Clinical Neurology
Yeliz Celik, Erik Thunstrom, Patrick J. Strollo Jr, Yuksel Peker
Summary: The study showed that CPAP had no significant impact on anxiety in CAD patients with nonsleepy OSA. However, a trend of increased anxiety scores was observed in patients adhering to CPAP treatment at 3 months and 12 months, while patients who were non-adherent to CPAP showed a decrease in anxiety scores.
Article
Neurosciences
Dominika Urbanik, Pawel Gac, Helena Martynowicz, Maciej Podgorski, Malgorzata Poreba, Grzegorz Mazur, Rafal Poreba
Summary: The study found that patients with OSA have increased abnormalities in 24-hour ECG Holter monitoring, which are positively correlated with higher AHI levels, with more frequent occurrences of SVT and VPC.
Article
Cardiac & Cardiovascular Systems
Kangjun Fan, Mingxin Gao, Wenyuan Yu, Hongli Liu, Liang Chen, Xiaohang Ding, Yang Yu
Summary: The study found that obstructive sleep apnea (OSA) was significantly associated with a higher incidence of perioperative myocardial infarction (PMI) following off-pump coronary artery bypass grafting (OPCABG), possibly due to exacerbated inflammatory response leading to severe coronary atherosclerotic lesions. Additionally, the efficacy of continuous positive airway pressure (CPAP) treatment for improving prognosis after CABG needs further investigation.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
