Tumor sequencing of African ancestry reveals differences in clinically relevant alterations across common cancers

Cancer statistics, 2022

(2022) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Cancer statistics for African American/Black People 2022

(2022) Angela N. Giaquinto et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Clinical and analytical validation of FoundationOne®CDx, a comprehensive genomic profiling assay for solid tumors

(2022) Coren A. Milbury et al.   PLoS One

The Genomics of Colorectal Cancer in Populations with African and European Ancestry

(2022) Parvathi A. Myer et al.   Cancer Discovery

Variation in targetable genomic alterations in non-small cell lung cancer by genetic ancestry, sex, smoking history, and histology

(2022) Elio Adib et al.   Genome Medicine

Racial Differences in Genomic Profiles of Breast Cancer

(2022) Neha Goel et al.   JAMA Network Open

Ancestry-driven recalibration of tumor mutational burden and disparate clinical outcomes in response to immune checkpoint inhibitors

(2022) Amin H. Nassar et al.   CANCER CELL

Distribution of KRASG12C Somatic Mutations across Race, Sex, and Cancer Type

(2021) Amin H. Nassar et al.   NEW ENGLAND JOURNAL OF MEDICINE

Enabling Precision Oncology Through Precision Diagnostics

(2020) Noah A. Brown et al.   Annual Review of Pathology-Mechanisms of Disease

Molecular profiling for precision cancer therapies

(2020) Eoghan R. Malone et al.   Genome Medicine

Comprehensive Analysis of Genetic Ancestry and Its Molecular Correlates in Cancer

(2020) Jian Carrot-Zhang et al.   CANCER CELL

Genomic Profiling of Prostate Cancers from Men with African and European Ancestry

(2020) Yusuke Koga et al.   CLINICAL CANCER RESEARCH

Racial Differences in Genomic Profiling of Prostate Cancer

(2020) Brandon A. Mahal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evaluation of USPSTF Lung Cancer Screening Guidelines Among African American Adult Smokers

(2019) Melinda C. Aldrich et al.   JAMA Oncology

Evaluating the quality of the 1000 genomes project data

(2019) Saurabh Belsare et al.   BMC GENOMICS

A Novel Next-Generation Sequencing Approach to Detecting Microsatellite Instability and Pan-Tumor Characterization of 1000 Microsatellite Instability–High Cases in 67,000 Patient Samples

(2019) Sally E. Trabucco et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

A computational approach to distinguish somatic vs. germline origin of genomic alterations from deep sequencing of cancer specimens without a matched normal

(2018) James X. Sun et al.   PLoS Computational Biology

Integrated Analysis of Genetic Ancestry and Genomic Alterations across Cancers

(2018) Jiao Yuan et al.   CANCER CELL

COSMIC: the Catalogue Of Somatic Mutations In Cancer

(2018) John G Tate et al.   NUCLEIC ACIDS RESEARCH

Racial/Ethnic Differences in Lung Cancer Incidence in the Multiethnic Cohort Study: An Update

(2018) Daniel O Stram et al.   JNCI-Journal of the National Cancer Institute

Rucaparib in relapsed, platinum-sensitive high-grade ovarian carcinoma (ARIEL2 Part 1): an international, multicentre, open-label, phase 2 trial

(2017) Elizabeth M Swisher et al.   LANCET ONCOLOGY

Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients

(2017) Ahmet Zehir et al.   NATURE MEDICINE

Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden

(2017) Zachary R. Chalmers et al.   Genome Medicine

Comparison of Prevalence and Types of Mutations in Lung Cancers Among Black and White Populations

(2017) Joshua D. Campbell et al.   JAMA Oncology

Comparison of Breast Cancer Molecular Features and Survival by African and European Ancestry in The Cancer Genome Atlas

(2017) Dezheng Huo et al.   JAMA Oncology

Comparative Analysis of Breast Cancer Phenotypes in African American, White American, and West Versus East African patients: Correlation Between African Ancestry and Triple-Negative Breast Cancer

(2016) Evelyn Jiagge et al.   ANNALS OF SURGICAL ONCOLOGY

Integrated genomic DNA/RNA profiling of hematologic malignancies in the clinical setting

(2016) J. He et al.   BLOOD

Analysis of protein-coding genetic variation in 60,706 humans

(2016) Monkol Lek et al.   NATURE

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing

(2013) Garrett M Frampton et al.   NATURE BIOTECHNOLOGY

Enhancements to the ADMIXTURE algorithm for individual ancestry estimation

(2011) David H Alexander et al.   BMC BIOINFORMATICS

Frequency and Type of Epidermal Growth Factor Receptor Mutations in African Americans with Non-small Cell Lung Cancer

(2011) Michele L. Cote et al.   Journal of Thoracic Oncology

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

Frequency of EGFR and KRAS Mutations in Lung Adenocarcinomas in African Americans

(2010) J. Matthew Reinersman et al.   Journal of Thoracic Oncology

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Fast model-based estimation of ancestry in unrelated individuals

(2009) D. H. Alexander et al.   GENOME RESEARCH

Characterizing the admixed African ancestry of African Americans

(2009) Fouad Zakharia et al.   GENOME BIOLOGY