Article
Anesthesiology
Kathryn J. Clark, Hans P. Sviggum, Adam K. Jacob, Katherine W. Arendt, Gerald W. Volcheck, Linda M. Szymanski, Emily E. Sharpe
Summary: Hereditary angioedema (HAE) is characterized by repeated episodes of localized submucosal or subcutaneous edema, potentially triggered by emotional stress, mechanical trauma, or intake of estrogens. Multidisciplinary care is essential for planning and executing the specialized care of these patients. Management includes extensive planning among obstetric, anesthesiology, and allergy and immunology teams.
Article
Medicine, General & Internal
Pawel Krawczyk, Remigiusz Jaskiewicz, Hubert Huras, Magdalena Kolak
Summary: There are many benefits of neuraxial anesthesia in the obstetric population. The study found a decrease in the use of general anesthesia during the COVID-19 pandemic in obstetric patients, suggesting the possibility of further reducing its use.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Health Care Sciences & Services
Antonio Coviello, Maria Vargas, Annachiara Marra, Ludovica Golino, Gabriele Saccone, Carmine Iacovazzo, Maria Grazia Frigo, Andrea Tognu, Marilena Ianniello, Pasquale Buonanno, Giuseppe Servillo
Summary: This study aimed to investigate the management protocols for COVID-19-positive obstetric patients and found that neuraxial anesthesia is safe for patients and healthcare workers, reducing aerosolization.
Article
Anesthesiology
Paloma Toledo, Cynthia A. Wong
Summary: This article reviews the contributions of Anesthesia & Analgesia and the International Anesthesia Research Society in promoting fundamental paradigm shifts in our understanding of obstetric anesthesiology.
ANESTHESIA AND ANALGESIA
(2022)
Article
Anesthesiology
Paloma Toledo, Cynthia A. A. Wong
Summary: Significant advancements have been made in the field of obstetric anesthesiology over the past century. This article reviews the contributions of Anesthesia & Analgesia journal and the International Anesthesia Research Society in shaping our understanding and practice of obstetric anesthesiology.
ANESTHESIA AND ANALGESIA
(2022)
Article
Public, Environmental & Occupational Health
Pierre M'pele, Justina O. Seyi-Olajide, Tarcisse Elongo, Jorn Lemvik, Delanyo Dovlo, Emmanuel A. Ameh
Summary: This study aimed to strengthen surgical, obstetric, and anesthesia care systems in Africa by engaging African leaders and key stakeholders. A baseline assessment was performed to identify the gaps in surgical care, and the findings were discussed during an International Symposium. The Dakar Declaration and its Regional Action Plan were created to improve access to surgical care by 2030 in Africa and were endorsed by Heads of State.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Anesthesiology
Mohamed Mohamed Tawfik, Mohamed Ahmed Tolba, Olfat Mostafa Ismail, Medhat Mikhail Messeha
Summary: This study compared preprocedural ultrasonography with landmark palpation for spinal anesthesia in obese parturients undergoing cesarean delivery. The results showed that, when performed by a single experienced anesthesiologist, preprocedural ultrasonography did not decrease the number of needle passes required to obtain free cerebrospinal fluid flow or improve other outcomes compared with landmark palpation.
REGIONAL ANESTHESIA AND PAIN MEDICINE
(2023)
Review
Anesthesiology
Olubukola Toyobo, Jean Guglielminotti, Doerthe Adriana Andreae, Michael H. Andreae
Summary: Health equity is crucial for obstetric anesthesia. Describing disparities in perinatal care process and health outcome is not enough; conceptualizing and framing disparity and hypothesizing and testing mechanisms and drivers are key. Measuring social determinants of health and meaningful perinatal processes and outcomes accurately is essential. Investigating precise mechanisms of disparity in obstetric care and testing efficient countermeasures are important. Rigorous prospective trials can help mitigate perinatal outcome disparities.
CURRENT OPINION IN ANESTHESIOLOGY
(2022)
Article
Medicine, General & Internal
Lorna Sweeney, Doris Lanz, Jahnavi Daru, Annika M. P. Rasijeff, Farzana Khanom, Amy Thomas, Angela Harden, Laura Green
Summary: The objective of this qualitative interview study was to understand the implementation of deferred consent procedures in the ACROBAT pilot trial and provide insights for planning a full-scale trial. The study found that deferred consent procedures raised concerns related to participants' conflation of research with clinical care and their ability to process trial information due to the stressful nature of recovery and newborn care.
Article
Anesthesiology
Hon Sen Tan, Sydney E. Reed, Jennifer E. Mehdiratta, Olga Diomede, Riley Landreth, Luke A. Gatta, Daniel Weikel, Ashraf S. Habib
Summary: In this study, there were no significant differences in the quality of labor analgesia between the dural puncture epidural and standard epidural techniques in obese parturients. Routine use of dural puncture epidural technique in obese parturients is not supported based on the findings of this study.
Article
Anesthesiology
Wenyuan Lyu, Penghui Wei, Wenxi Tang, Xiaotian Ma, Qiang Zheng, Haipeng Zhou, Jinfeng Zhou, Jianjun Li
Summary: This study aimed to determine an optimal method to prevent spinal hypotension. The findings showed that an initial bolus of 0.10 mu g/kg norepinephrine followed by continuous infusion resulted in a lower incidence of spinal hypotension, as well as reduced hypotension duration, rescue drug usage, and nausea/vomiting frequency.
ANESTHESIA AND ANALGESIA
(2023)
Article
Medicine, General & Internal
Jacob Weinstein, Amichai Shinfeld, Michal Simchen, Tal Cahan, Jonathan Frogel, Michael Arad, Haim Berkenstadt, Rafael Kuperstein
Summary: Pregnant women with Marfan syndrome at high risk of aortic dissection around delivery require multidisciplinary management, including proper cardio-obstetric care and adequate pain management. Anesthetic complications due to dural ectasia were not encountered during neuraxial block.
ISRAEL MEDICAL ASSOCIATION JOURNAL
(2021)
Article
Chemistry, Medicinal
Li-Juan Hu, Zhong Mei, Yan-Ping Shen, Hao-Tian Sun, Zhi-Min Sheng, Xin-Zhong Chen, Xiao-Wei Qian
Summary: Severe preeclamptic parturients require about a 34% reduction in phenylephrine dose compared to normotensive parturients.
DRUG DESIGN DEVELOPMENT AND THERAPY
(2022)
Review
Anesthesiology
Kamlesh Kumari, Kriti Chaudhary, Priyanka Sethi, Darshana Rathod, Tanvi Meshram, Nikhil Kothari, Ankur Sharma, Pradeep Bhatia, Surjit Singh
Summary: Norepinephrine and phenylephrine showed comparable efficacy in managing postspinal hypotension, but norepinephrine had a lower incidence of maternal bradycardia.
MINERVA ANESTESIOLOGICA
(2022)
Review
Anesthesiology
Alexandra E. Kisilevsky, Christie M. Addison, Alana M. Flexman
Summary: Trauma requiring neurosurgical intervention in the obstetric population is rare, and management must consider both maternal and fetal well-being. Maternal outcomes are generally poor in these cases, but the majority of fetal outcomes are good based on the limited data available.
JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY
(2021)
Editorial Material
Neurosciences
Christopher A. Guevara, Pamela Del Valle, Cynthia R. Mercedes
JOURNAL OF NEUROSCIENCE
(2020)
Letter
Biochemistry & Molecular Biology
Alexander W. Charney, Nicole W. Simons, Konstantinos Mouskas, Lauren Lepow, Esther Cheng, Jessica Le Berichel, Christie Chang, Robert Marvin, Diane Marie Del Valle, Sharlene Calorossi, Alona Lansky, Laura Walker, Manishkumar Patel, Hui Xie, Nancy Yi, Alex Yu, Gurpawan Kang, Lora E. Liharska, Emily Moya, Matthew Hartnett, Sandra Hatem, Lillian Wilkins, Melody Eaton, Hajra Jamal, Kevin Tuballes, Steven T. Chen, Jonathan Chung, Jocelyn Harris, Craig Batchelor, Jose Lacunza, Mahlet Yishak, Kimberly Argueta, Neha Karekar, Brian Lee, Geoffrey Kelly, Daniel Geanon, Diana Handler, John Leech, Hiyab Stefanos, Travis Dawson, Ieisha Scott, Nancy Francoeur, Jessica S. Johnson, Akhil Vaid, Benjamin S. Glicksberg, Girish N. Nadkarni, Eric E. Schadt, Bruce D. Gelb, Adeeb Rahman, Robert Sebra, Glenn Martin, Thomas Marron, Noam Beckmann, Seunghee Kim-Schulze, Sacha Gnjatic, Miriam Merad
Article
Multidisciplinary Sciences
Noam D. Beckmann, Phillip H. Comella, Esther Cheng, Lauren Lepow, Aviva G. Beckmann, Scott R. Tyler, Konstantinos Mouskas, Nicole W. Simons, Gabriel E. Hoffman, Nancy J. Francoeur, Diane Marie Del Valle, Gurpawan Kang, Anh Do, Emily Moya, Lillian Wilkins, Jessica Le Berichel, Christie Chang, Robert Marvin, Sharlene Calorossi, Alona Lansky, Laura Walker, Nancy Yi, Alex Yu, Jonathan Chung, Matthew Hartnett, Melody Eaton, Sandra Hatem, Hajra Jamal, Alara Akyatan, Alexandra Tabachnikova, Lora E. Liharska, Liam Cotter, Brian Fennessy, Akhil Vaid, Guillermo Barturen, Hardik Shah, Ying-chih Wang, Shwetha Hara Sridhar, Juan Soto, Swaroop Bose, Kent Madrid, Ethan Ellis, Elyze Merzier, Konstantinos Vlachos, Nataly Fishman, Manying Tin, Melissa Smith, Hui Xie, Manishkumar Patel, Kai Nie, Kimberly Argueta, Jocelyn Harris, Neha Karekar, Craig Batchelor, Jose Lacunza, Mahlet Yishak, Kevin Tuballes, Ieisha Scott, Arvind Kumar, Suraj Jaladanki, Charuta Agashe, Ryan Thompson, Evan Clark, Bojan Losic, Lauren Peters, Panagiotis Roussos, Jun Zhu, Wenhui Wang, Andrew Kasarskis, Benjamin S. Glicksberg, Girish Nadkarni, Dusan Bogunovic, Cordelia Elaiho, Sandeep Gangadharan, George Ofori-Amanfo, Kasey Alesso-Carra, Kenan Onel, Karen M. Wilson, Carmen Argmann, Supinda Bunyavanich, Marta E. Alarcon-Riquelme, Thomas U. Marron, Adeeb Rahman, Seunghee Kim-Schulze, Sacha Gnjatic, Bruce D. Gelb, Miriam Merad, Robert Sebra, Eric E. Schadt, Alexander W. Charney
Summary: Multisystem inflammatory syndrome in children (MIS-C) presents symptoms similar to Kawasaki disease and affects individuals under 21 years of age. RNA sequencing revealed signatures related to natural killer cell activation and CD8+ T cell exhaustion in the blood of MIS-C patients, showing similarities with Kawasaki disease.
NATURE COMMUNICATIONS
(2021)
Letter
Anesthesiology
Max M. Feinstein, Cynthia R. Mercedes, Matthew Sison, Jong Kim, Da Wi Shin, Daniel Katz, Marc Sherwin
JOURNAL OF CLINICAL ANESTHESIA
(2021)
Letter
Anesthesiology
Max M. Feinstein, Ira Schlosberg, Da Wi Shin, Cynthia R. Mercedes, Matthew Sison, Daniel Katz, Marc Sherwin
JOURNAL OF CLINICAL ANESTHESIA
(2022)
Article
Biochemical Research Methods
Guillaume Butler-Laporte, Edgar Gonzalez-Kozlova, Chen-Yang Su, Sirui Zhou, Tomoko Nakanishi, Elsa Brunet-Ratnasingham, David Morrison, Laetitia Laurent, Jonathan Afilalo, Marc Afilalo, Danielle Henry, Yiheng Chen, Julia Carrasco-Zanini, Yossi Farjoun, Maik Pietzner, Nofar Kimchi, Zaman Afrasiabi, Nardin Rezk, Meriem Bouab, Louis Petitjean, Charlotte Guzman, Xiaoqing Xue, Chris Tselios, Branka Vulesevic, Olumide Adeleye, Tala Abdullah, Noor Almamlouk, Yara Moussa, Chantal DeLuca, Naomi Duggan, Erwin Schurr, Nathalie Brassard, Madeleine Durand, Diane Marie Del Valle, Ryan Thompson, Mario A. Cedillo, Eric Schadt, Kai Nie, Nicole W. Simons, Konstantinos Mouskas, Nicolas Zaki, Manishkumar Patel, Hui Xie, Jocelyn Harris, Robert Marvin, Esther Cheng, Kevin Tuballes, Kimberly Argueta, Ieisha Scott, Celia M. T. Greenwood, Clare Paterson, Michael Hinterberg, Claudia Langenberg, Vincenzo Forgetta, Vincent Mooser, Thomas Marron, Noam Beckmann, Ephraim Kenigsberg, Alexander W. Charney, Seunghee Kim-Schulze, Miriam Merad, Daniel E. Kaufmann, Sacha Gnjatic, J. Brent Richards
Summary: COVID-19 is associated with changes in cytokines, interleukins, and other immune-related proteins. This study provides insights into the dynamic nature of these changes and their impact on severe illness and sex differences in COVID-19 outcomes.
CLINICAL PROTEOMICS
(2022)
Article
Biochemistry & Molecular Biology
Ryan C. Thompson, Nicole W. Simons, Lillian Wilkins, Esther Cheng, Diane Marie Del Valle, Gabriel E. Hoffman, Carlo Cervia, Brian Fennessy, Konstantinos Mouskas, Nancy J. Francoeur, Jessica S. Johnson, Lauren Lepow, Jessica Le Berichel, Christie Chang, Aviva G. Beckmann, Ying-chih Wang, Kai Nie, Nicholas Zaki, Kevin Tuballes, Vanessa Barcessat, Mario A. Cedillo, Dan Yuan, Laura Huckins, Panos Roussos, Thomas U. Marron, Benjamin S. Glicksberg, Girish Nadkarni, James R. Heath, Edgar Gonzalez-Kozlova, Onur Boyman, Seunghee Kim-Schulze, Robert Sebra, Miriam Merad, Sacha Gnjatic, Eric E. Schadt, Alexander W. Charney, Noam D. Beckmann
Summary: The post-acute sequelae of SARS-CoV-2 infection are already detectable during the acute phase and are associated with specific gene expression patterns and immune response, including antibody levels.