Article
Clinical Neurology
Han San Oh, Jin Woo Bae, Chang-eui Hong, Kang Min Kim, Dong Hyun Yoo, Hyun-Seung Kang, Young Dae Cho
Summary: This study compared the efficacy and safety of stent-assisted coil embolization (SACE) and flow-diverting stent (FDS) deployment for the treatment of unruptured vertebral artery dissecting aneurysms (VADAs). The results showed that FDS was more effective in reducing major recanalization compared to SACE. Overall, the assessments of procedural and delayed complications were similar for both methods.
Article
Neuroimaging
Ansaar T. Rai, SoHyun Boo, Jonathan Downer, Johannes DuPlessis, Riitta Rautio, Matias Sinisalo, Johanna Pekkola, Vinicius Carraro do Nascimento, Curtis Given, Tufail Patankar
Summary: This study aimed to quantify the variability and associated inaccuracies in physician preoperative planning of endovascular implant deployment and compared it with PreSize Neurovascular software simulations. The results showed that PreSize software had significantly higher accuracy than physician planning, demonstrating its potential to improve standard of practice.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2023)
Article
Neuroimaging
Yukiko Enomoto, Hirofumi Matsubara, Takuma Ishihara, Kenji Shoda, Daisuke Mizutani, Yusuke Egashira, Akira Ishii, Makoto Sakamoto, Kazutaka Sumita, Ichiro Nakagawa, Toshio Higashi, Shinichi Yoshimura
Summary: The optimal duration of dual antiplatelet therapy (DAPT) in patients with stent-assisted coiling (SAC) or flow-diversion (FD) for cerebral aneurysms remains unclear. A multicenter cohort study in Japan analyzed the cumulative event-free survival rates of patients receiving SAC/FD, finding that thromboembolic events rarely occurred beyond 30 days after the procedure. The results suggest that the duration of DAPT may be shortened if patients have a periprocedural period without events.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2023)
Article
Neuroimaging
Maher Sahnoun, Sebastien Soize, Pierre-Francois Manceau, Christophe Gelmini, Laurent Pierot
Summary: The study analyzed the use of WEB and stent in treating wide-neck bifurcation aneurysms, and the results showed that this combination therapy had a high efficacy with complete aneurysm occlusion rates of 88.2% and 92.9% at 6 and 12 months, respectively, without any reported morbidity or mortality.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2022)
Article
Clinical Neurology
David C. Lauzier, Samuel J. Cler, Joshua W. Osbun, Arindam R. Chatterjee, Christopher J. Moran, Akash P. Kansagra
Summary: Flow diversion with the pipeline embolization device (PED) for intracranial aneurysms may lead to angiographic stenosis, but dual antiplatelet therapy (DAPT) can effectively prevent stenosis progression and cerebral ischemia.
WORLD NEUROSURGERY
(2022)
Article
Neuroimaging
Chao Wang, Linggen Dong, Jian Liu, Yisen Zhang, Kun Wang, Peng Liu, Xinjian Yang, Ming Lv, Ying Zhang
Summary: In this study, the Atlas SAC and PED were compared for the treatment of proximal internal carotid artery aneurysms. The results showed that the two devices had similar midterm outcomes, but the Atlas SAC had a longer operation time and the PED resulted in higher hospital costs.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2023)
Article
Neuroimaging
Brooke L. Belanger, Rosalie Morrish, Davis McClarty, Colette Barnstable, Warren Muir, Soheil Ghazizadeh, Muneer Eesa, David Fiorella, John H. Wong, Chandar Sadasivan, Alim P. Mitha
Summary: The use of the ReSolv stent with the shelf technique improves flow diversion outcomes in bifurcation aneurysms. Compared to other stents, the shelfed ReSolv stent performs better in reducing perianeurysmal flow. Further research will help determine if the additional neck coverage leads to better long-term aneurysm occlusion.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2023)
Article
Neuroimaging
Yangchun Li, Stephanie H. Chen, Alejandro M. Spiotta, Pascal Jabbour, Michael R. Levitt, Peter Kan, Christoph J. Griessenauer, Adam S. Arthur, Joshua W. Osbun, Min S. Park, Nohra Chalouhi, Ahmad Sweid, Stacey Q. Wolfe, Kyle M. Fargen, Aaron S. Dumont, Travis M. Dumont, Marie-Christine Brunet, Samir Sur, Evan Luther, Allison Strickland, Dileep R. Yavagal, Eric C. Peterson, Clemens M. Schirmer, Oded Goren, Shamsher Dalal, Gregory Weiner, Axel Rosengart, Daniel Raper, Ching-Jen Chen, Peter Amenta, Tyler Scullen, Cory Michael Kelly, Christopher Young, Michael Nahhas, Eyad Almallouhi, Arunprasad Gunasekaran, Suhas Pai, Giuseppe Lanzino, Waleed Brinjikji, Mehdi Abbasi, David Dornbos, Nitin Goyal, Jeremy Peterson, Mohammad H. El-Ghanem, Robert M. Starke
Summary: This study retrospectively analyzed flow diversion cases for cerebral aneurysms from 14 institutions between 2010 and 2019. The results showed that TRA had lower access site complication rate and overall complication rate compared to TFA.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2021)
Article
Clinical Neurology
Xiheng Chen, Siming Gui, Linggen Dong, Longhui Zhang, Huijian Ge, Peng Liu, Youxiang Li, Ming Lv
Summary: This case report demonstrates successful treatment of DAR after PFED placement using WCS, providing a new treatment approach for similar cases in the future.
FRONTIERS IN NEUROLOGY
(2022)
Article
Engineering, Biomedical
Piotr Reorowicz, Zbigniew Tyfa, Damian Obidowski, Karol Wisniewski, Ludomir Stefanczyk, Krzysztof Jozwik, Michael Lee Levy
Summary: The Flow Diverter is a treatment method for fusiform aneurysms, commonly used for cerebral vascular anomalies but not for aortic aneurysms. Numerical simulation in a patient-specific model of abdominal aortic aneurysms allowed investigation and visualization of blood hemodynamics before and after stent implantation. The Flow Diverter stent significantly changed the flow pattern in the aneurysm region but did not affect blood flow to the renal arteries.
BIOCYBERNETICS AND BIOMEDICAL ENGINEERING
(2022)
Article
Clinical Neurology
Malvina Garner, Frederik Fries, Alena Haussmann, Michael Kettner, Armin Bachhuber, Wolfgang Reith, Umut Yilmaz
Summary: Flow diverter stents (FDS) are commonly used to treat intracranial aneurysms, but they pose a higher risk of specific complications compared to conventional stents. In this case report, a patient in their 30s with bilateral paraophthalmic internal carotid artery (ICA) aneurysms was treated with FDS. Reversible in-stent-stenosis (ISS) was initially found on both sides, resolved at the 1-year follow-up, but surprisingly recurred later and resolved again. This recurrence of ISS after resolution is a novel finding that requires further investigation to understand the mechanisms of FDS.
Article
Neuroimaging
Siming Gui, Xiheng Chen, Dachao Wei, Dingwei Deng, Wei You, Xiangyu Meng, Jian Lv, Junqiang Feng, Yudi Tang, Shu Yang, Ting Chen, Peng Liu, Huijian Ge, Hengwei Jin, Xinke Liu, Yuhua Jiang, Wei Feng, Youxiang LI
Summary: Flow diverters have greatly improved the treatment of intracranial aneurysms, but the delayed complications associated with their use are not well understood. This study evaluated the occurrence, severity, clinical outcomes, risk factors, and dynamic changes of in-stent stenosis (ISS) after treatment with a Pipeline embolization device (PED). The results show that ISS is a common, benign, and self-limiting complication of PED implantation in the Chinese population.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2023)
Article
Neuroimaging
Jawid Madjidyar, Emanuela Keller, Sebastian Winklhofer, Daniel Toth, Isabelle Barnaure, Tilman Schubert, Patrick Thurner, Jorn Fierstra, Jan Folkard Willms, Luca Regli, Zsolt Kulcsar
Summary: This study retrospectively analyzed the clinical outcomes of patients with ruptured cerebral aneurysms who underwent FDS reconstruction with single-antiplatelet therapy. The results showed that peri-interventional single-antiplatelet therapy was effective in preventing thromboembolic events and reducing re-bleeding, leading to partial or complete occlusion of the aneurysm.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2023)
Article
Medicine, General & Internal
Shao-Wei Feng, Chao-Bao Luo, Chien-Hui Lee, Feng-Chi Chang, Chung-Jung Lin
Summary: This study reports the experience and outcome of using flow-diverter stents (FDS) to manage intracranial aneurysms. The results show that FDS is safe and effective in managing unruptured aneurysms, particularly in smaller ones.
JOURNAL OF THE CHINESE MEDICAL ASSOCIATION
(2022)
Review
Neuroimaging
Ricardo A. Domingo, Shashwat Tripathi, Carlos Perez-Vega, Tito Vivas-Buitrago, Victor M. Lu, Nathan D. Todnem, Alfredo Quinones-Hinojosa, Rabih G. Tawk
Summary: This study compared the efficacy of SAC and FD treatment for non-saccular aneurysms in the posterior circulation, finding similar occlusion rates and clinical outcomes between the two techniques, with SAC showing a lower rate of periprocedural complications. Further research is needed to focus on reducing the risk of stroke with either modality.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2021)
Correction
Clinical Neurology
Ozgun Ozalay, Burcu Aksoy, Sebnem Tunay, Fatma Simsek, Swati Chandhoke, Omer Kitis, Cagdas Eker, Ali Saffet Gonul
PSYCHIATRY RESEARCH-NEUROIMAGING
(2016)
Article
Clinical Neurology
Ozgun Ozalay, Burcu Aksoy, Sebnem Tunay, Fatma Simsek, Swati Chandhoki, Omer Kitis, Cagdas Eker, Ali Saffet Gonul
PSYCHIATRY RESEARCH-NEUROIMAGING
(2016)
Article
Psychiatry
Ece Durmusoglu, Onur Ugurlu, Sebnem Akan, Fatma Simsek, Gozde Kizilates, Omer Kitis, Burcu Aksoy Ozkul, Cagdas Eker, Kerry L. Coburn, Ali Saffet Gonul
COMPREHENSIVE PSYCHIATRY
(2018)
Article
Clinical Neurology
Cagdas Eker, Fatma Simsek, Evrim Ebru Yilmazer, Omer Kitis, Cem Cinar, Ozlem Donat Eker, Kerry Coburn, Ali Saffet Gonul
Article
Clinical Neurology
Ozgun Ozalay, Cem Calli, Omer Kitis, M. Cagdas Eker, Ozlem Donat Eker, Erol Ozan, Kerry Coburn, Ali Saffet Gonul
JOURNAL OF AFFECTIVE DISORDERS
(2013)
Article
Neurosciences
Sonja M. C. de Zwarte, Rachel M. Brouwer, Ingrid Agartz, Martin Alda, Andre Aleman, Kathryn I. Alpert, Carrie E. Bearden, Alessandro Bertolino, Catherine Bois, Aurora Bonvino, Elvira Bramon, Elizabeth E. L. Buimer, Wiepke Cahn, Dara M. Cannon, Tyrone D. Cannon, Xavier Caseras, Josefina Castro-Fornieles, Qiang Chen, Yoonho Chung, Elena De la Serna, Annabella Di Giorgio, Gaelle E. Doucet, Mehmet Cagdas Eker, Susanne Erk, Scott C. Fears, Sonya F. Foley, Sophia Frangou, Andrew Frankland, Janice M. Fullerton, David C. Glahn, Vina M. Goghari, Aaron L. Goldman, Ali Saffet Gonul, Oliver Gruber, Lieuwe de Haan, Tomas Hajek, Emma L. Hawkins, Andreas Heinz, Manon H. J. Hillegers, Hilleke E. Hulshoff Pol, Christina M. Hultman, Martin Ingvar, Viktoria Johansson, Erik G. Jonsson, Fergus Kane, Matthew J. Kempton, Marinka M. G. Koenis, Miloslav Kopecek, Lydia Krabbendam, Bernd Kraemer, Stephen M. Lawrie, Rhoshel K. Lenroot, Machteld Marcelis, Jan-Bernard C. Marsman, Venkata S. Mattay, Colm McDonald, Andreas Meyer-Lindenberg, Stijn Michielse, Philip B. Mitchell, Dolores Moreno, Robin M. Murray, Benson Mwangi, Pablo Najt, Emma Neilson, Jason Newport, Jim van Os, Bronwyn Overs, Aysegul Ozerdem, Marco M. Picchioni, Anja Richter, Gloria Roberts, Aybala Saricicek Aydogan, Peter R. Schofield, Fatma Simsek, Jair C. Soares, Gisela Sugranyes, Timothea Toulopoulou, Giulia Tronchin, Henrik Walter, Lei Wang, Daniel R. Weinberger, Heather C. Whalley, Nefize Yalin, Ole A. Andreassen, Christopher R. K. Ching, Theo G. M. van Erp, Jessica A. Turner, Neda Jahanshad, Paul M. Thompson, Rene S. Kahn, Neeltje E. M. van Haren
BIOLOGICAL PSYCHIATRY
(2019)
Article
Neurosciences
Sonja M. C. de Zwarte, Rachel M. Brouwer, Ingrid Agartz, Martin Alda, Silvia Alonso-Lana, Carrie E. Bearden, Alessandro Bertolino, Aurora Bonvino, Elvira Bramon, Elizabeth E. L. Buimer, Wiepke Cahn, Erick J. Canales-Rodriguez, Dara M. Cannon, Tyrone D. Cannon, Xavier Caseras, Josefina Castro-Fornieles, Qiang Chen, Yoonho Chung, Elena de la Serna, Caterina del Mar Bonnin, Caroline Demro, Annabella Di Giorgio, Gaelle E. Doucet, Mehmet Cagdas Eker, Susanne Erk, Mar Fatjo-Vilas, Scott C. Fears, Sonya F. Foley, Sophia Frangou, Janice M. Fullerton, David C. Glahn, Vina M. Goghari, Jose M. Goikolea, Aaron L. Goldman, Ali Saffet Gonul, Oliver Gruber, Tomas Hajek, Emma L. Hawkins, Andreas Heinz, Ceren Hidiroglu Ongun, Manon H. J. Hillegers, Josselin Houenou, Hilleke E. Hulshoff Pol, Christina M. Hultman, Martin Ingvar, Viktoria Johansson, Erik G. Jonsson, Fergus Kane, Matthew J. Kempton, Marinka M. G. Koenis, Miloslav Kopecek, Bernd Kraemer, Stephen M. Lawrie, Rhoshel K. Lenroot, Machteld Marcelis, Venkata S. Mattay, Colm McDonald, Andreas Meyer-Lindenberg, Stijn Michielse, Philip B. Mitchell, Dolores Moreno, Robin M. Murray, Benson Mwangi, Leila Nabulsi, Jason Newport, Cheryl A. Olman, Jim van Os, Bronwyn J. Overs, Aysegul Ozerdem, Giulio Pergola, Marco M. Picchioni, Camille Piguet, Edith Pomarol-Clotet, Joaquim Radua, Ian S. Ramsay, Anja Richter, Gloria Roberts, Raymond Salvador, Aybala Saricicek Aydogan, Salvador Sarro, Peter R. Schofield, Esma M. Simsek, Fatma Simsek, Jair C. Soares, Scott R. Sponheim, Gisela Sugranyes, Timothea Toulopoulou, Giulia Tronchin, Eduard Vieta, Henrik Walter, Daniel R. Weinberger, Heather C. Whalley, Mon-Ju Wu, Nefize Yalin, Ole A. Andreassen, Christopher R. K. Ching, Sophia I. Thomopoulos, Theo G. M. van Erp, Neda Jahanshad, Paul M. Thompson, Rene S. Kahn, Neeltje E. M. van Haren
Summary: First-degree relatives of patients diagnosed with schizophrenia show widespread thinner cortex, while relatives of patients diagnosed with bipolar disorder show widespread larger cortical surface area. Both groups have lower IQ scores compared to controls, with schizophrenia relatives showing more pronounced brain abnormalities and bipolar disorder relatives showing weaker effects after adjusting for IQ or educational attainment.
HUMAN BRAIN MAPPING
(2022)
Article
Clinical Neurology
Hande Yildirim-Celik, Seda Eroglu, Kaya Oguz, Gulser Karakoc-Tugrul, Yigit Erdogan, Damla Isman-Haznedaroglu, Cagdas Eker, Ali Saffet Gonul
Summary: The study found that emotional contextual features play a role in facial emotion recognition, but this effect is not related to depression. Depressive patients have slower reaction times in recognizing facial emotions, possibly due to cognitive impairments.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Psychiatry
Kaan Keskin, Mehmet Cagdas Eker, Ali Saffet Gonul, Georg Northoff
Summary: This study aims to investigate the relationship between self-focus and emotion regulation in major depressive disorder (MDD) by examining the global brain activity in specific regions associated with the self. The results show that MDD patients exhibit abnormal emotion regulation, especially in the regulation of negative emotions. Additionally, there is increased global brain activity in regions related to the mental and exteroceptive self in MDD patients. These findings support the hypothesis that increased self-focus in MDD contributes to abnormal regulation of negative emotions.
TRANSLATIONAL PSYCHIATRY
(2023)
Article
Neurosciences
Burcu Ozkul, Cemre Candemir, Kaya Oguz, Seda Eroglu-Koc, Gozde Kizilates-Evin, Onur Ugurlu, Yigit Erdogan, Defne Dakota Mull, Mehmet Cagdas Eker, Omer Kitis, Ali Saffet Gonul
Summary: Group support plays a role in brain functioning, and the loss of social group support leads to reduced brain activity. Being part of a social group and receiving support enhances cognitive functioning, while the loss of group support activates brain regions associated with attention and survival.
Article
Psychiatry
Melek Hande Bulut Demir, Rahime Kaya, Ozgun Ozalay, Damla Isman Haznedaroglu, Yigit Erdogan, Omer Kitis, Tezan Bildik, Ali Saffet Gonul, Mehmet Cagdas Eker
Summary: The objective of this study was to explore the effects of sexual abuse on limbic and prefrontal cortex structures in adolescents. The findings showed that children with a history of sexual abuse had thinner prefrontal cortex, larger amygdala and hippocampus, and aberrations in threat detection, orientation, and response circuit. These adaptations may be beneficial in a dangerous environment in the short term.
SCANDINAVIAN JOURNAL OF CHILD AND ADOLESCENT PSYCHIATRY AND PSYCHOLOGY
(2023)
Article
Clinical Neurology
Nazan Dolapoglu, Banu Pinar Sarer Yurekli, Mehmet Cagdas Eker, Hayriye Elbi
Summary: The study showed a significantly higher frequency of metabolic syndrome in euthymic bipolar patients compared to the control group, although there was no significant difference in serum AgRP levels between the patient and control groups. Furthermore, there was no significant difference in serum AgRP levels between bipolar patients with metabolic syndrome and those without in both study groups.
NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY
(2021)
Proceedings Paper
Engineering, Biomedical
Ozkan Cigdem, Refik Soyak, Burhan Aydeniz, Kaya Oguz, Hasan Demirel, Omer Kitis, Cagdas Eker, Ali Saffet Gonul, Devrim Unay
2019 MEDICAL TECHNOLOGIES CONGRESS (TIPTEKNO)
(2019)
Meeting Abstract
Neurosciences
Sonja de Zwarte, Rachel Brouwer, Manon Hillegers, Wiepke Cahn, Hilleke Hulshoff Pol, Rene Kahn, Kathryn Alpert, Lei Wang, Elvira Bramon, Fergus Kane, Robin Murray, Tomas Hajek, Martin Alda, Gloria Roberts, Philip Mitchell, Peter Schofield, Janice Fullerton, Anja Richter, Oliver Gruber, Aurora Bonvino, Alessandro Bertolino, Annabella Di Giorgio, Xavier Caseras, Ali Saffet Gonul, Mehmet Cagdas Eker, Fatma Simsek, Scott Fears, Carrie Bearden, David Glahn, Theo van Erp, Paul Thompson, Ole Andreassen, Jessica Turner, Neeltje van Haren
BIOLOGICAL PSYCHIATRY
(2017)
