Beneficial effects of recombinant CER-001 high-density lipoprotein infusion in sepsis: results from a bench to bedside translational research project

Sepsis-associated acute kidney injury—treatment standard

(2023) Alexander Zarbock et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Replenishing HDL with synthetic HDL has multiple protective effects against sepsis in mice

(2022) Ling Guo et al.   Science Signaling

First Recombinant High-Density Lipoprotein Particles Administration in a Severe ICU COVID-19 Patient, a Multi-Omics Exploratory Investigation

(2022) Sébastien Tanaka et al.   Biomedicines

Cytokine Storm—Definition, Causes, and Implications

(2022) Dominik Jarczak et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Relationship between liver dysfunction, lipoprotein concentration and mortality during sepsis

(2022) Sébastien Tanaka et al.   PLoS One

Apolipoprotein-A-I for severe COVID-19-induced hyperinflammatory states: A prospective case study

(2022) Stanislas Faguer et al.   Frontiers in Pharmacology

Altered high-density lipoprotein composition and functions during severe COVID-19

(2021) Floran Begue et al.   Scientific Reports

Relationship between lipoprotein concentrations and short-term and 1-year mortality in intensive care unit septic patients: results from the HIGHSEPS study

(2021) Sébastien Tanaka et al.   Annals of Intensive Care

PMMA-Based Continuous Hemofiltration Modulated Complement Activation and Renal Dysfunction in LPS-Induced Acute Kidney Injury

(2021) Alessandra Stasi et al.   Frontiers in Immunology

sTREM-1 is a specific biomarker of TREM-1 pathway activation

(2021) Lucie Jolly et al.   Cellular & Molecular Immunology

Diagnostic and prognostic predictive values of circulating sTREM-1 in sepsis: A meta-analysis

(2021) Qin Qin et al.   INFECTION GENETICS AND EVOLUTION

Multifaced Roles of HDL in Sepsis and SARS-CoV-2 Infection: Renal Implications

(2021) Alessandra Stasi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Lipid and lipoprotein predictors of functional outcomes and long-term mortality after surgical sepsis

(2021) Faheem W. Guirgis et al.   Annals of Intensive Care

Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021

(2021) Laura Evans et al.   INTENSIVE CARE MEDICINE

Prognostic value of apolipoproteins in COVID-19 patients: A systematic review and meta-analysis

(2021) Juan R. Ulloque-Badaracco et al.   Travel Medicine and Infectious Disease

Reconstituted High-density Lipoprotein Therapy Improves Survival in Mouse Models of Sepsis

(2020) Sébastien Tanaka et al.   ANESTHESIOLOGY

Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the Global Burden of Disease Study

(2020) Kristina E Rudd et al.   LANCET

Sepsis therapies: learning from 30 years of failure of translational research to propose new leads

(2020) Jean‐Marc Cavaillon et al.   EMBO Molecular Medicine

Incidence and mortality of hospital- and ICU-treated sepsis: results from an updated and expanded systematic review and meta-analysis

(2020) C. Fleischmann-Struzek et al.   INTENSIVE CARE MEDICINE

Digging deeper into bile proteome

(2020) Sergio Ciordia et al.   Journal of Proteomics

High levels of gut-homing immunoglobulin A–positive+B lymphocytes support the pathogenic role of intestinal mucosal hyperresponsiveness in immunoglobulin A nephropathy patients

(2020) Fabio Sallustio et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Renal progenitor cells revert LPS-induced endothelial-to-mesenchymal transition by secreting CXCL6, SAA4, and BPIFA2 antiseptic peptides

(2019) Fabio Sallustio et al.   FASEB JOURNAL

LPS-Binding Protein Modulates Acute Renal Fibrosis by Inducing Pericyte-to-Myofibroblast Trans-Differentiation through TLR-4 Signaling

(2019) Giuseppe Castellano et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mechanisms of Organ Dysfunction in Sepsis

(2018) Rachel Pool et al.   CRITICAL CARE CLINICS

Effect of Serial Infusions of CER-001, a Pre-β High-Density Lipoprotein Mimetic, on Coronary Atherosclerosis in Patients Following Acute Coronary Syndromes in the CER-001 Atherosclerosis Regression Acute Coronary Syndrome Trial

(2018) Stephen J. Nicholls et al.   JAMA Cardiology

Effect of Targeted Polymyxin B Hemoperfusion on 28-Day Mortality in Patients With Septic Shock and Elevated Endotoxin Level

(2018) R. Phillip Dellinger et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Acute kidney injury in sepsis

(2017) Rinaldo Bellomo et al.   INTENSIVE CARE MEDICINE

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

(2016) Mervyn Singer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Human SR-BI and SR-BII Potentiate Lipopolysaccharide-Induced Inflammation and Acute Liver and Kidney Injury in Mice

(2016) Irina N. Baranova et al.   JOURNAL OF IMMUNOLOGY

Complement Modulation of Anti-Aging Factor Klotho in Ischemia/Reperfusion Injury and Delayed Graft Function

(2015) G. Castellano et al.   AMERICAN JOURNAL OF TRANSPLANTATION

HDL in sepsis – risk factor and therapeutic approach

(2015) Emily E. Morin et al.   Frontiers in Pharmacology

Pleiotropic Effects of HDL: Towards New Therapeutic Areas for HDL-Targeted Interventions

(2014) S.C. Gordts et al.   CURRENT MOLECULAR MEDICINE

Effects of the high-density lipoprotein mimetic agent CER-001 on coronary atherosclerosis in patients with acute coronary syndromes: a randomized trial

(2014) J.-C. Tardif et al.   EUROPEAN HEART JOURNAL

Endothelial-to-mesenchymal transition and renal fibrosis in ischaemia/reperfusion injury are mediated by complement anaphylatoxins and Akt pathway

(2014) C. Curci et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

CER-001, a HDL-mimetic, stimulates the reverse lipid transport and atherosclerosis regression in high cholesterol diet-fed LDL-receptor deficient mice

(2013) Claudine Tardy et al.   ATHEROSCLEROSIS

Circulating sICAM-1 and sE-Selectin as biomarker of infection and prognosis in patients with systemic inflammatory response syndrome

(2013) Raúl de Pablo et al.   European Journal of Internal Medicine

High-volume versus standard-volume haemofiltration for septic shock patients with acute kidney injury (IVOIRE study): a multicentre randomized controlled trial

(2013) Olivier Joannes-Boyau et al.   INTENSIVE CARE MEDICINE

Lipids: a key player in the battle between the host and microorganisms

(2012) Kenneth R. Feingold et al.   JOURNAL OF LIPID RESEARCH

Notice

(2012)   Kidney International Supplements

Therapeutic Targeting of Classical and Lectin Pathways of Complement Protects from Ischemia-Reperfusion-Induced Renal Damage

(2010) Giuseppe Castellano et al.   AMERICAN JOURNAL OF PATHOLOGY

Changes in HDL-associated apolipoproteins relate to mortality in human sepsis and correlate to monocyte and platelet activation

(2009) Stefan Barlage et al.   INTENSIVE CARE MEDICINE

Early Use of Polymyxin B Hemoperfusion in Abdominal Septic Shock

(2009) Dinna N. Cruz et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION