Direct evaluation of polarity of the ligand binding pocket in retinoid X receptor using a fluorescent solvatochromic agonist

Fluorescence properties of retinoid X receptor antagonist NEt-SB

(2020) Shoya Yamada et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Convenient Retinoid X Receptor Binding Assay Based on Fluorescence Change of the Antagonist NEt-C343

(2020) Kayo Yukawa-Takamatsu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of a “Gatekeeper” Antagonist that Blocks Entry Pathway to Retinoid X Receptors (RXRs) without Allosteric Ligand Inhibition in Permissive RXR Heterodimers

(2020) Masaki Watanabe et al.   JOURNAL OF MEDICINAL CHEMISTRY

Competitive Binding Assay with an Umbelliferone-Based Fluorescent Rexinoid for Retinoid X Receptor Ligand Screening

(2019) Shoya Yamada et al.   JOURNAL OF MEDICINAL CHEMISTRY

Retinoid X Receptor Antagonists

(2018) Masaki Watanabe et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Large-scale detection of drug off-targets: hypotheses for drug repurposing and understanding side-effects

(2017) Matthieu Chartier et al.   BMC Pharmacology & Toxicology

Red Emitting Coumarin—Azo Dyes : Synthesis, Characterization, Linear and Non-linear Optical Properties-Experimental and Computational Approach

(2016) Abhinav B. Tathe et al.   JOURNAL OF FLUORESCENCE

Modeling absorption and fluorescence solvatochromism with QM/Classical approaches

(2015) Benedetta Mennucci   INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY

The role of ligand efficiency metrics in drug discovery

(2014) Andrew L. Hopkins et al.   NATURE REVIEWS DRUG DISCOVERY

A Structure-Based Model for Predicting Serum Albumin Binding

(2014) Katrina W. Lexa et al.   PLoS One

Optical sensor arrays for chemical sensing: the optoelectronic nose

(2013) Jon R. Askim et al.   CHEMICAL SOCIETY REVIEWS

Defining the Communication between Agonist and Coactivator Binding in the Retinoid X Receptor α Ligand Binding Domain

(2013) LeeAnn J. Boerma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Design of UV–vis Absorption and Emission Properties in Organic Fluorophores: Toward Larger Bathochromic Shifts, Enhanced Molar Extinction Coefficients, and Greater Stokes Shifts

(2013) Xiaogang Liu et al.   Journal of Physical Chemistry C

Rational Approaches to Improving Selectivity in Drug Design

(2012) David J. Huggins et al.   JOURNAL OF MEDICINAL CHEMISTRY

Development of a quinoxaline-based fluorescent probe for quantitative estimation of protein binding site polarity

(2011) Kentaro Kudo et al.   CHEMICAL COMMUNICATIONS

Fluorescent retinoid X receptor ligands for fluorescence polarization assay

(2010) Shoya Yamada et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The “Phantom Effect” of the Rexinoid LG100754: Structural and Functional Insights

(2010) Yoshiteru Sato et al.   PLoS One

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Fluorescence Quenching to Study Protein-ligand Binding: Common Errors

(2009) Marco van de Weert   JOURNAL OF FLUORESCENCE

Physical Properties (Density, Excess Molar Volume, Viscosity, Surface Tension, and Refractive Index) of Ethanol + Glycerol

(2008) Abdullah S. Alkindi et al.   JOURNAL OF CHEMICAL AND ENGINEERING DATA