Disengagement of somatostatin neurons from lateral septum circuitry by oxytocin and vasopressin restores social-fear extinction and suppresses aggression outbursts in Prader-Willi syndrome model

Magel2 truncation alters select behavioral and physiological outcomes in a rat model of Schaaf-Yang syndrome

(2023) Derek L. Reznik et al.   Disease Models & Mechanisms

Oxytocin receptors in the Magel2 mouse model of autism: Specific region, age, sex and oxytocin treatment effects

(2023) Valentina Gigliucci et al.   Frontiers in Neuroscience

Top-down regulation of motivated behaviors via lateral septum sub-circuits

(2022) Antoine Besnard et al.   MOLECULAR PSYCHIATRY

Linking oxytocin and arginine vasopressin signaling abnormalities to social behavior impairments in Prader-Willi syndrome

(2022) Ozge Oztan et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Social trauma engages lateral septum circuitry to occlude social reward

(2022) Long Li et al.   NATURE

Aggression in Group-Housed Male Mice: A Systematic Review

(2022) Elin M. Weber et al.   Animals

Oxytocin and vasopressin within the ventral and dorsal lateral septum modulate aggression in female rats

(2021) Vinícius Elias de Moura Oliveira et al.   Nature Communications

Phenotypic spectrum and mechanism analysis of Schaff Yang syndrome

(2021) Yanjie Duan et al.   MEDICINE

Oxytocin administration in neonates shapes hippocampal circuitry and restores social behavior in a mouse model of autism

(2021) Alessandra Bertoni et al.   MOLECULAR PSYCHIATRY

Dopamine promotes aggression in mice via ventral tegmental area to lateral septum projections

(2021) Darshini Mahadevia et al.   Nature Communications

Wireless Optogenetic Stimulation of Oxytocin Neurons in a Semi-natural Setup Dynamically Elevates Both Pro-social and Agonistic Behaviors

(2020) Sergey Anpilov et al.   NEURON

Loss of MAGEL2 in Prader-Willi syndrome leads to decreased secretory granule and neuropeptide production

(2020) Helen Chen et al.   JCI Insight

Attend Less, Fear More: Elevated Distress to Social Threat in Toddlers With Autism Spectrum Disorder

(2020) Suzanne L. Macari et al.   Autism Research

Correction of vasopressin deficit in the lateral septum ameliorates social deficits of mouse autism model

(2020) Amélie M. Borie et al.   JOURNAL OF CLINICAL INVESTIGATION

Early Screening and Risk Factors of Autism Spectrum Disorder in a Large Cohort of Chinese Patients With Prader-Willi Syndrome

(2020) Xuejun Kong et al.   Frontiers in Psychiatry

A Disinhibitory Microcircuit Mediates Conditioned Social Fear in the Prefrontal Cortex

(2019) Haifeng Xu et al.   NEURON

Dorsolateral septum somatostatin interneurons gate mobility to calibrate context-specific behavioral fear responses

(2019) Antoine Besnard et al.   NATURE NEUROSCIENCE

Guanfacine Extended Release for the Reduction of Aggression, Attention-Deficit/Hyperactivity Disorder Symptoms, and Self-Injurious Behavior in Prader-Willi Syndrome—A Retrospective Cohort Study

(2019) Deepan Singh et al.   JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY

A randomized placebo-controlled pilot trial shows that intranasal vasopressin improves social deficits in children with autism

(2019) Karen J. Parker et al.   Science Translational Medicine

A phase 2 clinical trial of a vasopressin V1a receptor antagonist shows improved adaptive behaviors in men with autism spectrum disorder

(2019) Federico Bolognani et al.   Science Translational Medicine

Oxytocin Signaling in the Central Amygdala Modulates Emotion Discrimination in Mice

(2019) Valentina Ferretti et al.   CURRENT BIOLOGY

Oxytocin Signaling in the Lateral Septum Prevents Social Fear during Lactation

(2018) Rohit Menon et al.   CURRENT BIOLOGY

Drd3 Signaling in the Lateral Septum Mediates Early Life Stress-Induced Social Dysfunction

(2018) Sora Shin et al.   NEURON

The characteristics of temper outbursts in Prader-Willi syndrome

(2018) Lauren J. Rice et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

A circuit from hippocampal CA2 to lateral septum disinhibits social aggression

(2018) Felix Leroy et al.   NATURE

Inactivation of Magel2 suppresses oxytocin neurons through synaptic excitation-inhibition imbalance

(2018) Tayfun Ates et al.   NEUROBIOLOGY OF DISEASE

Magel2 knockout mice manifest altered social phenotypes and a deficit in preference for social novelty

(2017) M. D. Fountain et al.   GENES BRAIN AND BEHAVIOR

Diagnoses and characteristics of autism spectrum disorders in children with Prader-Willi syndrome

(2017) Elisabeth M. Dykens et al.   Journal of Neurodevelopmental Disorders

Reduced gamma-aminobutyric acid is associated with emotional and behavioral problems in Prader-Willi syndrome

(2016) Lauren J. Rice et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

An Inhibitory Septum to Lateral Hypothalamus Circuit That Suppresses Feeding

(2016) P. Sweeney et al.   JOURNAL OF NEUROSCIENCE

Central Amygdala Somatostatin Neurons Gate Passive and Active Defensive Behaviors

(2016) Kai Yu et al.   JOURNAL OF NEUROSCIENCE

Lessons learned from studying syndromic autism spectrum disorders

(2016) Yehezkel Sztainberg et al.   NATURE NEUROSCIENCE

Oxytocin and Autism Spectrum Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

(2016) Yoon Ooi et al.   PHARMACOPSYCHIATRY

The developmental trajectory of disruptive behavior in Down syndrome, fragile X syndrome, Prader-Willi syndrome and Williams syndrome

(2015) Lauren J. Rice et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

An Early Postnatal Oxytocin Treatment Prevents Social and Learning Deficits in Adult Mice Deficient for Magel2, a Gene Involved in Prader-Willi Syndrome and Autism

(2015) Hamid Meziane et al.   BIOLOGICAL PSYCHIATRY

The role of brain somatostatin receptor 2 in the regulation of feeding and drinking behavior

(2015) Andreas Stengel et al.   HORMONES AND BEHAVIOR

Oxytocin Mediates Entrainment of Sensory Stimuli to Social Cues of Opposing Valence

(2015) Han Kyoung Choe et al.   NEURON

Oxytocin enhances orienting to social information in a selective group of high-functioning male adults with autism spectrum disorder

(2015) M. Althaus et al.   NEUROPSYCHOLOGIA

Control of Stress-Induced Persistent Anxiety by an Extra-Amygdala Septohypothalamic Circuit

(2014) Todd E. Anthony et al.   CELL

Brain Oxytocin in Social Fear Conditioning and Its Extinction: Involvement of the Lateral Septum

(2014) Iulia Zoicas et al.   NEUROPSYCHOPHARMACOLOGY

Effects of Intranasal Oxytocin on the Neural Basis of Face Processing in Autism Spectrum Disorder

(2013) Gregor Domes et al.   BIOLOGICAL PSYCHIATRY

Truncating mutations of MAGEL2 cause Prader-Willi phenotypes and autism

(2013) Christian P Schaaf et al.   NATURE GENETICS

Social Fear Conditioning: A Novel and Specific Animal Model to Study Social Anxiety Disorder

(2012) Iulia Toth et al.   NEUROPSYCHOPHARMACOLOGY

Distinct correlations of vasopressin release within the lateral septum and the bed nucleus of the stria terminalis with the display of intermale aggression

(2010) Alexa H. Veenema et al.   HORMONES AND BEHAVIOR

A single postnatal injection of oxytocin rescues the lethal feeding behaviour in mouse newborns deficient for the imprinted Magel2 gene

(2010) Fabienne Schaller et al.   HUMAN MOLECULAR GENETICS

Regionally reduced brain volume, altered serotonin neurochemistry, and abnormal behavior in mice null for the circadian rhythm output geneMagel2

(2009) Rebecca E. Mercer et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS