Distinct roles of core autophagy-related genes in zebrafish definitive hematopoiesis

Autophagy is dispensable for the maintenance of hematopoietic stem cells in neonates

(2021) Michihiro Hashimoto et al.   Blood Advances

A single-cell resolution developmental atlas of hematopoietic stem and progenitor cell expansion in zebrafish

(2021) Jun Xia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans

(2021) Jack J. Collier et al.   NEW ENGLAND JOURNAL OF MEDICINE

Definitive hematopoietic stem cells minimally contribute to embryonic hematopoiesis

(2021) Bianca A. Ulloa et al.   Cell Reports

1-phenyl 2-thiourea (PTU) activates autophagy in zebrafish embryos

(2020) Xiang-Ke Chen et al.   Autophagy

Autophagy Is Required for Maturation of Surfactant-Containing Lamellar Bodies in the Lung and Swim Bladder

(2020) Hideaki Morishita et al.   Cell Reports

Macrophages target Salmonella by Lc3-associated phagocytosis in a systemic infection model

(2019) Samrah Masud et al.   Autophagy

Autophagy-Independent Functions of the Autophagy Machinery

(2019) Lorenzo Galluzzi et al.   CELL

Myeloid loss of Beclin 1 promotes PD-L1hi precursor B cell lymphoma development

(2019) Peng Tan et al.   JOURNAL OF CLINICAL INVESTIGATION

Highly Efficient CRISPR-Cas9-Based Methods for Generating Deletion Mutations and F0 Embryos that Lack Gene Function in Zebrafish

(2019) Kazuyuki Hoshijima et al.   DEVELOPMENTAL CELL

Beclin 1 deficiency causes hepatic cell apoptosis via endoplasmic reticulum stress in zebrafish larvae

(2019) Guoping Dong et al.   FEBS LETTERS

Autophagy maintains the metabolism and function of young and old stem cells

(2017) Theodore T. Ho et al.   NATURE

The circadian clock regulates autophagy directly through the nuclear hormone receptor Nr1d1/Rev-erbα and indirectly via Cebpb/(C/ebpβ) in zebrafish

(2016) Guodong Huang et al.   Autophagy

Nutrient-regulated Phosphorylation of ATG13 Inhibits Starvation-induced Autophagy

(2016) Cindy Puente et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Atg9A trafficking through the recycling endosomes is required for autophagosome formation

(2016) Kenta Imai et al.   JOURNAL OF CELL SCIENCE

An Autophagic Flux Probe that Releases an Internal Control

(2016) Takeshi Kaizuka et al.   MOLECULAR CELL

A rapid and high content assay that measures cyto-ID-stained autophagic compartments and estimates autophagy flux with potential clinical applications

(2015) Sujuan Guo et al.   Autophagy

Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction

(2015) Xiao-E Jia et al.   CELL RESEARCH

CRISPRscan: designing highly efficient sgRNAs for CRISPR-Cas9 targeting in vivo

(2015) Miguel A Moreno-Mateos et al.   NATURE METHODS

Beclin 1 bridges autophagy, apoptosis and differentiation

(2014) Jianrong Wang   Autophagy

Autophagy is essential for cardiac morphogenesis during vertebrate development

(2014) Eunmyong Lee et al.   Autophagy

Estrogen Defines the Dorsal-Ventral Limit of VEGF Regulation to Specify the Location of the Hemogenic Endothelial Niche

(2014) Kelli J. Carroll et al.   DEVELOPMENTAL CELL

Sin3a-associated Hdac1 and Hdac2 are essential for hematopoietic stem cell homeostasis and contribute differentially to hematopoiesis

(2014) M. R. Heideman et al.   HAEMATOLOGICA

Il-1  and Reactive Oxygen Species Differentially Regulate Neutrophil Directional Migration and Basal Random Motility in a Zebrafish Injury-Induced Inflammation Model

(2014) B. Yan et al.   JOURNAL OF IMMUNOLOGY

Lipidation of the LC3/GABARAP family of autophagy proteins relies on a membrane-curvature-sensing domain in Atg3

(2014) Sangeeta Nath et al.   NATURE CELL BIOLOGY

Ulk1-mediated Atg5-independent macroautophagy mediates elimination of mitochondria from embryonic reticulocytes

(2014) Shinya Honda et al.   Nature Communications

Autophagy and human diseases

(2013) Peidu Jiang et al.   CELL RESEARCH

Atg6 is required for multiple vesicle trafficking pathways and hematopoiesis in Drosophila

(2013) B. V. Shravage et al.   DEVELOPMENT

Novel cardiovascular gene functions revealed via systematic phenotype prediction in zebrafish

(2013) G. Musso et al.   DEVELOPMENT

The zebrafish reference genome sequence and its relationship to the human genome

(2013) Kerstin Howe et al.   NATURE

A network of epigenetic regulators guides developmental haematopoiesis in vivo

(2013) Hsuan-Ting Huang et al.   NATURE CELL BIOLOGY

Innate Immune Response to Streptococcus iniae Infection in Zebrafish Larvae

(2012) Elizabeth A. Harvie et al.   INFECTION AND IMMUNITY

In vivo genome editing using a high-efficiency TALEN system

(2012) Victoria M. Bedell et al.   NATURE

Lack of autophagy in the hematopoietic system leads to loss of hematopoietic stem cell function and dysregulated myeloid proliferation

(2011) Monika Mortensen et al.   Autophagy

Expression pattern and functions of autophagy-related geneatg5in zebrafish organogenesis

(2011) Zhanying Hu et al.   Autophagy

The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance

(2011) Monika Mortensen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Canonical and non-canonical autophagy: variations on a common theme of self-eating?

(2011) Patrice Codogno et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

FIP200 is required for the cell-autonomous maintenance of fetal hematopoietic stem cells

(2010) F. Liu et al.   BLOOD

Differential Regulation of Protrusion and Polarity by PI(3)K during Neutrophil Motility in Live Zebrafish

(2010) Sa Kan Yoo et al.   DEVELOPMENTAL CELL

Assaying autophagic activity in transgenic GFP-Lc3 and GFP-Gabarap zebrafish embryos

(2009) Congcong He et al.   Autophagy

Discovery of Atg5/Atg7-independent alternative macroautophagy

(2009) Yuya Nishida et al.   NATURE

A Primer for Morpholino Use in Zebrafish

(2009) Brent R. Bill et al.   Zebrafish