Aspergillusin chronic lung disease: Modeling what goes on in the airways

Practice Guidelines for the Diagnosis and Management of Aspergillosis: 2016 Update by the Infectious Diseases Society of America

(2016) Thomas F. Patterson et al.   CLINICAL INFECTIOUS DISEASES

Recent advances in the understanding of the Aspergillus fumigatus cell wall

(2016) Mark J. Lee et al.   JOURNAL OF MICROBIOLOGY

IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis

(2016) Rossana G. Iannitti et al.   Nature Communications

Aspergillus fumigatus proteases, Asp f 5 and Asp f 13, are essential for airway inflammation and remodelling in a murine inhalation model

(2015) S. Namvar et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Evolution of the Immune Response to Chronic Airway Colonization with Aspergillus fumigatus Hyphae

(2015) Mirjam Urb et al.   INFECTION AND IMMUNITY

Monitoring inflammation and airway remodeling by fluorescence molecular tomography in a chronic asthma model

(2015) Fabio Stellari et al.   Journal of Translational Medicine

B Cells Play Key Roles in Th2-Type Airway Immune Responses in Mice Exposed to Natural Airborne Allergens

(2015) Li Yin Drake et al.   PLoS One

Regulatory T Cells Control Antigen-Specific Expansion of Tfh Cell Number and Humoral Immune Responses via the Coreceptor CTLA-4

(2014) James Badger Wing et al.   IMMUNITY

IL-37 Inhibits Inflammasome Activation and Disease Severity in Murine Aspergillosis

(2014) Silvia Moretti et al.   PLoS Pathogens

Fungal allergy in asthma–state of the art and research needs

(2014) David W Denning et al.   Clinical and Translational Allergy

Allergic bronchopulmonary aspergillosis: review of literature and proposal of new diagnostic and classification criteria

(2013) R. Agarwal et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Effectiveness of voriconazole in the treatment of Aspergillus fumigatus–associated asthma (EVITA3 study)

(2013) Joshua Agbetile et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

What is the clinical significance of filamentous fungi positive sputum cultures in patients with cystic fibrosis?

(2013) Jane C. Liu et al.   Journal of Cystic Fibrosis

Differential Effects of Dexamethasone and Itraconazole onAspergillus fumigatus-Exacerbated Allergic Airway Inflammation in a Murine Model of Mite-Sensitized Asthma

(2013) Hiroto Matsuse et al.   RESPIRATION

Aspergillusbronchitis without significant immunocompromise

(2012) Ales Chrdle et al.   Annals of the New York Academy of Sciences

Interleukin-17 Drives Pulmonary Eosinophilia following Repeated Exposure to Aspergillus fumigatus Conidia

(2012) Benjamin J. Murdock et al.   INFECTION AND IMMUNITY

Dectin-1 and IL-17A Suppress Murine Asthma Induced by Aspergillus versicolor but Not Cladosporium cladosporioides Due to Differences in  -Glucan Surface Exposure

(2012) R. A. Mintz-Cole et al.   JOURNAL OF IMMUNOLOGY

ICOS-Expressing CD4 T Cells Induced via TLR4 in the Nasal Mucosa Are Capable of Inhibiting Experimental Allergic Asthma

(2012) K. H. Shalaby et al.   JOURNAL OF IMMUNOLOGY

 -Chain-Deficient Mice Possess B-1 Cells and Produce IgG and IgE, but Not IgA, following Systemic Sensitization and Inhalational Challenge in a Fungal Asthma Model

(2012) S. Ghosh et al.   JOURNAL OF IMMUNOLOGY

Global burden of allergic bronchopulmonary aspergillosis with asthma and its complication chronic pulmonary aspergillosis in adults

(2012) David W. Denning et al.   MEDICAL MYCOLOGY

Cystic Fibrosis Transmembrane Conductance Regulator Regulates Epithelial Cell Response toAspergillusand Resultant Pulmonary Inflammation

(2011) Neelkamal Chaudhary et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The protective role of TLR6 in a mouse model of asthma is mediated by IL-23 and IL-17A

(2011) Ana Paula Moreira et al.   JOURNAL OF CLINICAL INVESTIGATION

TNF-  from inflammatory dendritic cells (DCs) regulates lung IL-17A/IL-5 levels and neutrophilia versus eosinophilia during persistent fungal infection

(2011) M. Fei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aspergillus fumigatus colonization in cystic fibrosis: implications for lung function?

(2010) A.M.M. de Vrankrijker et al.   CLINICAL MICROBIOLOGY AND INFECTION

A comparison between intratracheal and inhalation delivery of Aspergillus fumigatus conidia in the development of fungal allergic asthma in C57BL/6 mice

(2010) Amali E. Samarasinghe et al.   Fungal Biology

Differential mechanisms of resistance to sublethal systemic Aspergillus fumigatus infection in immunocompetent BALB/c and C57BL/6 mice

(2010) Ivana Mirkov et al.   IMMUNOBIOLOGY

Coevolution of TH1, TH2, and TH17 Responses during Repeated Pulmonary Exposure toAspergillus fumigatusConidia

(2010) Benjamin J. Murdock et al.   INFECTION AND IMMUNITY

Serum amyloid P attenuates M2 macrophage activation and protects against fungal spore–induced allergic airway disease

(2010) Ana Paula Moreira et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

An inhalation model of airway allergic response to inhalation of environmentalAspergillus fumigatusconidia in sensitized BALB/c mice

(2010) Scott A. Hoselton et al.   MEDICAL MYCOLOGY

Clinical risk factors for invasive aspergillosis

(2010) John W. Baddley   MEDICAL MYCOLOGY

The Effect of Chronic Infection With Aspergillus fumigatus on Lung Function and Hospitalization in Patients With Cystic Fibrosis

(2009) Reshma Amin et al.   CHEST

Intranasal CpG Therapy Attenuated Experimental Fungal Asthma in a TLR9-Dependent and -Independent Manner

(2009) Hemanth Ramaprakash et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Combined sensitization of mice to extracts of dust mite, ragweed, and Aspergillus species breaks through tolerance and establishes chronic features of asthma

(2009) Nicholas Goplen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IL-6 Is Required for Airway Mucus Production Induced by Inhaled Fungal Allergens

(2009) W. A. Neveu et al.   JOURNAL OF IMMUNOLOGY

Occurrence and relevance of filamentous fungi in respiratory secretions of patients with cystic fibrosis – a review

(2009) Marc Pihet et al.   MEDICAL MYCOLOGY

Link between allergic asthma and airway mucosal infection suggested by proteinase-secreting household fungi

(2009) P Porter et al.   Mucosal Immunology

Effects of the Phosphodiesterase Type 4 Inhibitor Roflumilast on Early and Late Allergic Response and Airway Hyperresponsiveness in Aspergillus-fumigatus-Sensitized Mice

(2009) Heinz-Gerd Hoymann et al.   PHARMACOLOGY

Randomized Controlled Trial of Oral Antifungal Treatment for Severe Asthma with Fungal Sensitization

(2008) David W. Denning et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Transcriptional Profiling Identifies a Role for BrlA in the Response to Nitrogen Depletion and for StuA in the Regulation of Secondary Metabolite Clusters inAspergillus fumigatus

(2008) Kwame Twumasi-Boateng et al.   EUKARYOTIC CELL

Essential role of IFNβ and CD38 in TNFα-induced airway smooth muscle hyper-responsiveness

(2008) Deepika Jain et al.   IMMUNOBIOLOGY

Toll-Like Receptor 9 Modulates Immune Responses to Aspergillus fumigatus Conidia in Immunodeficient and Allergic Mice

(2008) H. Ramaprakash et al.   INFECTION AND IMMUNITY

In Vivo Analysis of Aspergillus fumigatus Developmental Gene Expression Determined by Real-Time Reverse Transcription-PCR

(2008) F. N. Gravelat et al.   INFECTION AND IMMUNITY

Toll like receptor-2 modulates both innate and adaptive immune responses during chronic fungal asthma in mice

(2008) K. F. Buckland et al.   INFLAMMATION RESEARCH