2-Geranyl-1-methoxyerythrabyssin II alleviates lipid accumulation and inflammation in hepatocytes through AMPK activation and AKT inhibition
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
2-Geranyl-1-methoxyerythrabyssin II alleviates lipid accumulation and inflammation in hepatocytes through AMPK activation and AKT inhibition
Authors
Keywords
-
Journal
ARCHIVES OF PHARMACAL RESEARCH
Volume 46, Issue 9-10, Pages 808-824
Publisher
Springer Science and Business Media LLC
Online
2023-10-02
DOI
10.1007/s12272-023-01464-z
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Anti-adipogenic activity of maackiain and ononin is mediated via inhibition of PPARγ in human adipocytes
- (2022) Saveta G. Mladenova et al. BIOMEDICINE & PHARMACOTHERAPY
- Polyphenolic Compounds from Lespedeza bicolor Protect Neuronal Cells from Oxidative Stress
- (2022) Darya V. Tarbeeva et al. Antioxidants
- Salidroside activates the AMP‐activated protein kinase pathway to suppress non‐alcoholic steatohepatitis
- (2021) Manli Hu et al. HEPATOLOGY
- Direct small molecule ADaM-site AMPK activators reveal an AMPKγ3-independent mechanism for blood glucose lowering
- (2021) Nicolas O. Jørgensen et al. Molecular Metabolism
- A Narrative Review on the Role of AMPK on De Novo Lipogenesis in Non-Alcoholic Fatty Liver Disease: Evidence from Human Studies
- (2021) Christian von Loeffelholz et al. Cells
- Tumor necrosis factor-α signaling in nonalcoholic steatohepatitis and targeted therapies
- (2021) Sijia Lu et al. Journal of Genetics and Genomics
- Maackiain Protects the Kidneys of Type 2 Diabetic Rats via Modulating the Nrf2/HO-1 and TLR4/NF-κB/Caspase-3 Pathways
- (2021) Jiahong Guo et al. Drug Design Development and Therapy
- (+)-Dehydrovomifoliol Alleviates Oleic Acid-Induced Lipid Accumulation in HepG2 Cells via the PPARα–FGF21 Pathway
- (2021) Yiyuan Xi et al. Frontiers in Pharmacology
- Asian perspective on NAFLD-associated HCC
- (2021) Terry Cheuk-Fung Yip et al. JOURNAL OF HEPATOLOGY
- An AMPK–caspase-6 axis controls liver damage in nonalcoholic steatohepatitis
- (2020) Peng Zhao et al. SCIENCE
- Polyphenolic Compounds from Lespedeza Bicolor Root Bark Inhibit Progression of Human Prostate Cancer Cells via Induction of Apoptosis and Cell Cycle Arrest
- (2020) Sergey A. Dyshlovoy et al. Biomolecules
- Mutual regulation of metabolic processes and proinflammatory NF-κB signaling
- (2020) Michael Kracht et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Unexpected Rapid Increase in the Burden of Nonalcoholic Fatty Liver Disease in China From 2008 to 2018: A Systematic Review and Meta‐Analysis
- (2019) Feng Zhou et al. HEPATOLOGY
- The Global Epidemiology of NAFLD and NASH in Patients with type 2 diabetes: A Systematic Review and Meta-analysis
- (2019) Zobair M. Younossi et al. JOURNAL OF HEPATOLOGY
- Antiproliferative Pterocarpans and Coumestans from Lespedeza bicolor
- (2019) Nguyen Thi Thanh Thuy et al. JOURNAL OF NATURAL PRODUCTS
- Scoparone prevents IL-1β-induced inflammatory response in human osteoarthritis chondrocytes through the PI3K/Akt/NF-κB pathway
- (2018) Chao Lu et al. BIOMEDICINE & PHARMACOTHERAPY
- Non-alcoholic Steatohepatitis is the Fastest Growing Cause of Hepatocellular Carcinoma in Liver Transplant Candidates
- (2018) Zobair Younossi et al. Clinical Gastroenterology and Hepatology
- AMPK Re-Activation Suppresses Hepatic Steatosis but its Downregulation Does Not Promote Fatty Liver Development
- (2018) Nadia Boudaba et al. EBioMedicine
- Acyl Glucuronide Metabolites of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic Acid (PF-06409577) and Related Indole-3-carboxylic Acid Derivatives are Direct Activators of Adenosine Monophosphate-Activated Protein Kinase (AMPK)
- (2018) Tim F. Ryder et al. JOURNAL OF MEDICINAL CHEMISTRY
- RCSB Protein Data Bank: biological macromolecular structures enabling research and education in fundamental biology, biomedicine, biotechnology and energy
- (2018) Stephen K Burley et al. NUCLEIC ACIDS RESEARCH
- Pterocarpan scaffold: A natural lead molecule with diverse pharmacological properties
- (2017) Chelliah Selvam et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases
- (2017) Naga Chalasani et al. HEPATOLOGY
- PharmMapper 2017 update: a web server for potential drug target identification with a comprehensive target pharmacophore database
- (2017) Xia Wang et al. NUCLEIC ACIDS RESEARCH
- AMPK as a Therapeutic Target for Treating Metabolic Diseases
- (2017) Emily A. Day et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Treatment of nonalcoholic fatty liver disease: role of AMPK
- (2016) Brennan K. Smith et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Beneficial Effects of Pterocarpan-High Soybean Leaf Extract on Metabolic Syndrome in Overweight and Obese Korean Subjects: Randomized Controlled Trial
- (2016) Ri Ryu et al. Nutrients
- The Roles of mTOR Complexes in Lipid Metabolism
- (2015) Alexandre Caron et al. Annual Review of Nutrition
- SREBP-1c overactivates ROS-mediated hepatic NF-κB inflammatory pathway in dairy cows with fatty liver
- (2015) Xinwei Li et al. CELLULAR SIGNALLING
- Nonalcoholic Steatohepatitis Is the Second Leading Etiology of Liver Disease Among Adults Awaiting Liver Transplantation in the United States
- (2015) Robert J. Wong et al. GASTROENTEROLOGY
- Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin
- (2013) Morgan D Fullerton et al. NATURE MEDICINE
- Structural basis of AMPK regulation by small molecule activators
- (2013) Bing Xiao et al. Nature Communications
- Potent inhibition of bacterial neuraminidase activity by pterocarpans isolated from the roots of Lespedeza bicolor
- (2011) Hyun Sim Woo et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Akt Stimulates Hepatic SREBP1c and Lipogenesis through Parallel mTORC1-Dependent and Independent Pathways
- (2011) Jessica L. Yecies et al. Cell Metabolism
- NF-κB, Inflammation, and Metabolic Disease
- (2011) Rebecca G. Baker et al. Cell Metabolism
- Peroxisome proliferator-activated receptor-α agonist, Wy 14 643, improves metabolic indices, steatosis and ballooning in diabetic mice with non-alcoholic steatohepatitis
- (2011) Claire Z Larter et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1
- (2010) Katrin Düvel et al. MOLECULAR CELL
- AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility
- (2009) Garrett M. Morris et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
- (2009) Da Wei Huang et al. Nature Protocols
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now