LZTS3/TAGLN Suppresses Cancer Progression in Human Colorectal Adenocarcinoma Through Regulating Cell Proliferation, Migration, and Actin Cytoskeleton

β-Trcp and CK1δ-mediated degradation of LZTS2 activates PI3K/AKT signaling to drive tumorigenesis and metastasis in hepatocellular carcinoma

(2021) Yanwei Lu et al.   ONCOGENE

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Long non-coding RNA Lnc-LALC facilitates colorectal cancer liver metastasis via epigenetically silencing LZTS1

(2021) Chuan Zhang et al.   Cell Death & Disease

ciRS-7 is a prognostic biomarker and potential gene therapy target for renal cell carcinoma

(2021) Weipu Mao et al.   Molecular Cancer

Transgelin is a poor prognostic factor associated with advanced colorectal cancer (CRC) stage promoting tumor growth and migration in a TGFβ-dependent manner

(2020) Mona Elsafadi et al.   Cell Death & Disease

Transgelin 2 is required for embryo implantation by promoting actin polymerization

(2019) Xiaoling Liang et al.   FASEB JOURNAL

Transgelin, a p53 and PTEN-Upregulated Gene, Inhibits the Cell Proliferation and Invasion of Human Bladder Carcinoma Cells in Vitro and in Vivo

(2019) Tsui et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

LncRNA GLCC1 promotes colorectal carcinogenesis and glucose metabolism by stabilizing c-Myc

(2019) Jiayin Tang et al.   Nature Communications

Targeting signalling pathways and the immune microenvironment of cancer stem cells — a clinical update

(2019) Joseph A. Clara et al.   Nature Reviews Clinical Oncology

LZTS2 inhibits PI3K/AKT activation and radioresistance in nasopharyngeal carcinoma by interacting with p85

(2018) Shuangbing Xu et al.   CANCER LETTERS

Quantitative Proteomics Identify the Possible Tumor Suppressive Role of Protease-Activated Receptor-4 in Esophageal Squamous Cell Carcinoma Cells

(2018) Ming Wang et al.   PATHOLOGY & ONCOLOGY RESEARCH

Prosapip1-Dependent Synaptic Adaptations in the Nucleus Accumbens Drive Alcohol Intake, Seeking, and Reward

(2017) Sophie Laguesse et al.   NEURON

The tumor-suppressor gene LZTS1 suppresses colorectal cancer proliferation through inhibition of the AKT–mTOR signaling pathway

(2015) Wei Zhou et al.   CANCER LETTERS

Improving survival by exploiting tumour dependence on stabilized mutant p53 for treatment

(2015) E. M. Alexandrova et al.   NATURE

Silencing of Jagged1 inhibits cell growth and invasion in colorectal cancer

(2014) Y Dai et al.   Cell Death & Disease

MicroRNA-135b promotes lung cancer metastasis by regulating multiple targets in the Hippo pathway and LZTS1

(2013) Ching-Wen Lin et al.   Nature Communications

MRK003, a γ-secretase inhibitor exhibits promising in vitro pre-clinical activity in multiple myeloma and non-Hodgkin's lymphoma

(2011) V Ramakrishnan et al.   LEUKEMIA

Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade

(2010) Jianhui Ma et al.   JOURNAL OF CLINICAL INVESTIGATION

Transgelin as a suppressor is associated with poor prognosis in colorectal carcinoma patients

(2009) Liang Zhao et al.   MODERN PATHOLOGY

Association of survival and disease progression with chromosomal instability: A genomic exploration of colorectal cancer

(2009) M. Sheffer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA