Journal
CHEMICAL COMMUNICATIONS
Volume 51, Issue 89, Pages 16107-16110Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc05508c
Keywords
-
Categories
Funding
- MEXT, Japan
Ask authors/readers for more resources
Described herein is a highly enantioselective synthesis of fused piperidine and pyrrolidine derivatives with all-carbon stereogenic centers. The enantioselective reductive amination from Cs-symmetric 1,3-dione derivatives proceeded in a highly stereoselective manner by taking advantage of the desymmetrization approach to afford fused heterocycles with contiguous stereogenic centers in good to excellent enantioselectivities (up to 98% ee).
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available