A phase I study of the safety, tolerability, and pharmacokinetics of contezolid acefosamil after intravenous and oral administration in healthy Chinese subjects

In vivo pharmacodynamic study of contezolid acefosamil, a prodrug of contezolid for oral and intravenous administration

(2023) Xiu-Kun Wang et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

A Phase III multicentre, randomized, double-blind trial to evaluate the efficacy and safety of oral contezolid versus linezolid in adults with complicated skin and soft tissue infections

(2022) Xu Zhao et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Discovery of Antibacterial Contezolid Acefosamil: Innovative O-Acyl Phosphoramidate Prodrug for IV and Oral Therapies

(2022) Jinqian Liu et al.   ACS Medicinal Chemistry Letters

Nonclinical Evaluation of Antibacterial Oxazolidinones Contezolid and Contezolid Acefosamil with Low Serotonergic Neurotoxicity

(2021) Wen Wang et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Contezolid: First Approval

(2021) Sheridan M. Hoy   DRUGS

Population Pharmacokinetics Study of Contezolid (MRX-I), a Novel Oxazolidinone Antibacterial Agent, in Chinese Patients

(2020) Li Li et al.   CLINICAL THERAPEUTICS

A Retrospective Analysis of the Effect of Tigecycline on Coagulation Function

(2019) Bing Leng et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Short-term Safety, Tolerability, and Pharmacokinetics of MRX-I, an Oxazolidinone Antibacterial Agent, in Healthy Chinese Subjects

(2018) Xiaojie Wu et al.   CLINICAL THERAPEUTICS

In Vivo Activity of LCB 01-0699, a Prodrug of LCB 01-0648, against Staphylococcus aureus

(2017) Sang-Hun Oh et al.   MOLECULES

Linezolid Induced Adverse Drug Reactions - An Update

(2015) Kamal Kishor et al.   CURRENT DRUG METABOLISM

In VivoAntibacterial Activity of MRX-I, a New Oxazolidinone

(2014) Cong-Ran Li et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Tigecycline Treatment Causes a Decrease in Fibrinogen Levels

(2014) Qian Zhang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Single- and Multiple-Dose Pharmacokinetics and Absolute Bioavailability of Tedizolid

(2014) Shawn Flanagan et al.   PHARMACOTHERAPY

Methicillin-Resistant Staphylococcus aureus Infections

(2013) Paul S. Pottinger   MEDICAL CLINICS OF NORTH AMERICA

Pharmacokinetics of Tedizolid Following Oral Administration: Single and Multiple Dose, Effect of Food, and Comparison of Two Solid Forms of the Prodrug

(2013) Shawn D. Flanagan et al.   PHARMACOTHERAPY

Analysis of Linezolid-Associated Hematologic Toxicities in a Large Veterans Affairs Medical Center

(2010) Quentin Minson et al.   PHARMACOTHERAPY