Article
Critical Care Medicine
John Austin McCandlish, Chinara Feizullayeva, Alex C. Spyropoulos, Paul P. Cronin, Jason J. Naidich, Benjamin Brenner, Thomas McGinn, Pina C. Sanelli, Stuart L. Cohen
Summary: The study found that the diagnostic guidelines for suspected pulmonary embolism in pregnant women proposed by the American Thoracic Society and Society of Thoracic Radiology are cost-effective and generate better health outcomes compared to guidelines proposed by other medical societies.
Article
Public, Environmental & Occupational Health
Fiammetta Maria Bozzani, Nicky McCreesh, Karin Diaconu, Indira Govender, Richard G. White, Karina Kielmann, Alison D. Grant, Anna Vassall
Summary: An economic evaluation conducted in two clinics in South Africa showed that tuberculosis infection prevention and control measures, including improving ventilation and maximizing the use of existing systems, are cost-effective and should be implemented within the country's health system.
Article
Medicine, General & Internal
Kevin Duan, Francisco Rodriguez Garza, Hugo Flores, Daniel Palazuelos, Jimena Maza, Luis Alberto Martinez-Juarez, Patrick F. Elliott, Elena Moreno Lazaro, Natan Enriquez Rios, Gustavo Nigenda, Lindsay Palazuelos, Ryan K. McBain
Summary: CESPEC is a cost-effective community-based model of diabetes care for patients in rural Mexico, providing more health-adjusted years at a lower cost compared to usual care.
Article
Public, Environmental & Occupational Health
Akashdeep Singh Chauhan, Deepshikha Sharma, Abha Mehndiratta, Nidhi Gupta, Basant Garg, Amneet P. Kumar, Shankar Prinja
Summary: This study assessed the accuracy of results generated from adaptive HTA approaches for economic evaluation specific to the Indian context. The findings showed significant variations in adapted cost estimates while quality-adjusted life-years did not differ much. There is a need to interpret findings from aHTA methods with caution and develop more robust approaches for cost adjustment in the future.
Article
Oncology
Tima Mohammadi, Daphne P. Guh, Alexander C. T. Tam, Reka E. Pataky, Peter C. Black, Alan So, Larry D. Lynd, Wei Zhang, Annalijn I. Conklin
Summary: In this study, a modeling framework was constructed to evaluate the cost-effectiveness of using a new risk assessment tool (RAT) for biopsy decision-making in men with gray zone prostate-specific antigen (PSA) levels. The RAT based on an existing biomarker's characteristics was found to be a dominant strategy, resulting in cost savings and improved quality-adjusted life years (QALY) compared to the current standard of care (SOC). The findings suggest that implementing a more accurate RAT for biopsy guidance can be cost-effective.
Article
Medicine, General & Internal
Victoria McCreanor, Alexandra Nowbar, Christopher Rajkumar, Adrian G. Barnett, Darrel Francis, Nicholas Graves, William E. Boden, William S. Weintraub, Rasha Al-Lamee, William A. Parsonage
Summary: The cost-effectiveness of percutaneous coronary intervention (PCI) compared with placebo in patients with single-vessel coronary artery disease and angina on anti-anginal medication exceeds the threshold used by the National Institute of Health and Care Excellence. The estimated Incremental cost-effectiveness ratio (ICER) for PCI is £90,218/QALY gained, and the results were robust under sensitivity analyses.
Article
Pharmacology & Pharmacy
Xikui Lu, Lu Zhang, Hangxing Huang, Xiangping Wu, Zhenting Wang, Ling Huang, Jingyang Li, Huimin Yu, Hongyan Zhang, Jian Xiao
Summary: This study aimed to evaluate the economic advantages of joint management of cancer pain by physicians and pharmacists in clinics from the perspective of the Chinese healthcare system. The results demonstrated that the participation of pharmacists in joint cancer pain clinic services led to improved pain management for patients and showed clear cost-effectiveness advantages.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Medicine, General & Internal
Wei Li, Li Wan
Summary: The study aimed to evaluate the cost-effectiveness of lenvatinib plus transarterial chemoembolisation (TACE) compared to lenvatinib alone for the treatment of advanced hepatocellular carcinoma (HCC). The results suggest that lenvatinib plus TACE may be a cost-effective strategy for the first-line treatment of advanced HCC in China.
Article
Medicine, General & Internal
Mohammad Tasavon Gholamhoseini, Heidar Sharafi, Helena H. L. Borba, Seyed Moayed Alavian, Asma Sabermahani, Behzad Hajarizadeh
Summary: This study evaluates the cost-effectiveness of different treatment scenarios for hepatitis C virus (HCV) in Iran, a resource-limited setting. The results show that a pan-genotypic generic direct-acting antiviral (DAA) regimen, such as SOF/VEL, is cost-effective and potentially cost-saving compared to scenarios that require pretreatment HCV genotype tests.
Article
Medicine, General & Internal
Carrie B. Dolan, Samuel A. Agyemang, Brian Clare, Charles Coleman, Bill Richter, Emily Robertson, Justice Nonvignon
Summary: The study aimed to examine the cost-effectiveness of six types of surgical interventions in St. Vincent and the Grenadines from 2002 to 2019, and found that most paediatric surgical interventions were cost-effective. Investing in paediatric surgical interventions in limited resource settings could yield substantial economic benefits.
Article
Public, Environmental & Occupational Health
Jeffrey N. Bone, Asif R. Khowaja, Marianne Vidler, Beth A. Payne, Mrutyunjaya B. Bellad, Shivaprasad S. Goudar, Ashalata A. Mallapur, Khatia Munguambe, Rahat N. Qureshi, Charfudin Sacoor, Esperanca Sevene, Geert W. J. Frederix, Zulfiqar A. Bhutta, Craig Mitton, Laura A. Magee, Peter von Dadelszen
Summary: The aim of this study was to assess the cost-effectiveness of the CLIP intervention for pregnancy hypertension, and it was found that women who received >= 8 CLIP contacts may be more cost-effective in India, Pakistan, and Mozambique.
Article
Medicine, General & Internal
Nuha Bazeer, Alec Miners, Ian Roberts, Haleema Shakur-Still, Vipul Jairath, Jack Williams
Summary: This economic evaluation compared the cost-effectiveness of TXA versus no-TXA for acute gastrointestinal bleeding, showing that TXA administration, despite being inexpensive, is unlikely to be cost-effective. TXA was associated with marginally fewer life years and quality-adjusted life years, and lower costs compared to treatment without TXA.
Review
Medicine, General & Internal
Tanja Rombey, Helene Eckhardt, Joern Kiselev, Julia Silzle, Tim Mathes, Wilm Quentin
Summary: This study aimed to evaluate the cost-effectiveness of prehabilitation for patients awaiting elective surgery compared to usual preoperative care. The results suggest that prehabilitation is cost-effective for these patients, although there is a risk of publication bias and low study quality.
Article
Public, Environmental & Occupational Health
Chen Liu, Jae Hyoung Lee, Amanda J. Gupta, Austin Tucker, Chris Larkin, Patricia Turimumahoro, Achilles Katamba, J. Lucian Davis, David Dowdy
Summary: Human-centred design (HCD) is a problem-solving approach used to develop global health interventions. The cost-effectiveness of HCD depends on the number of clients reached and the trade-off between HCD costs and intervention delivery costs.
Article
Public, Environmental & Occupational Health
Shan Jiang, Yitong Wang, Junwen Zhou, Yawen Jiang, Gordon Guo-En Liu, Jing Wu
Summary: The inclusion of future unrelated medical costs can improve the internal and external consistency of economic evaluation and the comparability of results between different jurisdictions. However, more research is needed to further explore this issue.