Intravenous albumin in cirrhosis: Updated clinical uses and novel perspectives

A randomized-controlled trial comparing 20% albumin to plasmalyte in patients with cirrhosis and sepsis-induced hypotension [ALPS trial]

(2022) Rakhi Maiwall et al.   JOURNAL OF HEPATOLOGY

Long-term albumin treatment in patients with cirrhosis and ascites

(2022) Paolo Caraceni et al.   JOURNAL OF HEPATOLOGY

A double-blind randomized placebo-controlled trial of albumin in outpatients with hepatic encephalopathy: HEAL study

(2022) Andrew Fagan et al.   JOURNAL OF HEPATOLOGY

Determination of effective albumin in patients with decompensated cirrhosis: clinical and prognostic implications

(2021) Maurizio Baldassarre et al.   HEPATOLOGY

A Randomized Trial of Albumin Infusions in Hospitalized Patients with Cirrhosis

(2021) Louise China et al.   NEW ENGLAND JOURNAL OF MEDICINE

Comparison of 5% human albumin and normal saline for fluid resuscitation in sepsis induced hypotension among patients with cirrhosis (FRISC study): a randomized controlled trial

(2021) Cyriac Abby Philips et al.   Hepatology International

Albumin in decompensated cirrhosis: new concepts and perspectives

(2020) Mauro Bernardi et al.   GUT

On-treatment serum albumin level can guide long-term treatment in patients with cirrhosis and uncomplicated ascites

(2020) Paolo Caraceni et al.   JOURNAL OF HEPATOLOGY

Albumin internalizes and inhibits endosomal TLR signaling in leukocytes from patients with decompensated cirrhosis

(2020) Mireia Casulleras et al.   Science Translational Medicine

Effects of Albumin Treatment on Systemic and Portal Hemodynamics and Systemic Inflammation in Patients With Decompensated Cirrhosis

(2019) Javier Fernández et al.   GASTROENTEROLOGY

Efficacy of Albumin Treatment for Patients with Cirrhosis and Infections Unrelated to Spontaneous Bacterial Peritonitis

(2019) Javier Fernández et al.   Clinical Gastroenterology and Hepatology

Paracentesis‐induced circulatory dysfunction with modest‐volume paracentesis is partly ameliorated by albumin infusion in ACLF

(2019) Vinod Arora et al.   HEPATOLOGY

EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis

(2018) Paolo Angeli et al.   JOURNAL OF HEPATOLOGY

Long-term albumin administration in decompensated cirrhosis (ANSWER): an open-label randomised trial

(2018) Paolo Caraceni et al.   LANCET

Long-term administration of human albumin improves survival in patients with cirrhosis and refractory ascites

(2018) Marco Di Pascoli et al.   LIVER INTERNATIONAL

Randomized controlled trial comparing lactulose plus albumin versus lactulose alone for treatment of hepatic encephalopathy

(2017) Barjesh Chander Sharma et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Albumin in chronic liver disease: structure, functions and therapeutic implications

(2015) Rosaria Spinella et al.   Hepatology International

Effect of albumin in cirrhotic patients with infection other than spontaneous bacterial peritonitis. A randomized trial

(2015) Thierry Thévenot et al.   JOURNAL OF HEPATOLOGY

Immunosuppression in acutely decompensated cirrhosis is mediated by prostaglandin E2

(2014) Alastair J O'Brien et al.   NATURE MEDICINE

Effects of intravenous albumin in patients with cirrhosis and episodic hepatic encephalopathy: A randomized double-blind study

(2013) Macarena Simón-Talero et al.   JOURNAL OF HEPATOLOGY

Positive cardiac inotropic effect of albumin infusion in rodents with cirrhosis and ascites: molecular mechanisms

(2012) Alessia Bortoluzzi et al.   HEPATOLOGY

Albumin for bacterial infections other than spontaneous bacterial peritonitis in cirrhosis. A randomized, controlled study

(2012) Mónica Guevara et al.   JOURNAL OF HEPATOLOGY

Albumin infusion in patients undergoing large-volume paracentesis: A meta-analysis of randomized trials

(2011) Mauro Bernardi et al.   HEPATOLOGY

Alterations in the functional capacity of albumin in patients with decompensated cirrhosis is associated with increased mortality

(2009) Rajiv Jalan et al.   HEPATOLOGY