Journal
CHEMICAL COMMUNICATIONS
Volume 51, Issue 77, Pages 14465-14468Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc06105a
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Funding
- National Natural Science Foundation of China [21475013]
- Doctoral Fund of Ministry of Education of China [20120181120070]
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We report here the newly discovered photocatalytic activity of the dsDNA-SYBR Green I (SG) complex, which can catalyze the oxidation of 3,3',5,5'-tetramethylbenzidine (TMB) under light irradiation corresponding to the excitation of the dsDNA-SG complex. Themost appealing feature of the photocatalytic system here is that it can be obtained using random DNA sequences that can form a duplex. Considering the universality of the photooxidase, a label-free and universal platform was proposed for highly sensitive visual bioassays.
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