Inhibiting HMGB1 with Glycyrrhizic Acid Protects Brain Injury after DAI via Its Anti-Inflammatory Effect

Anti-inflammatory Activity of Magnesium Isoglycyrrhizinate Through Inhibition of Phospholipase A2/Arachidonic Acid Pathway

(2015) Chunfeng Xie et al.   INFLAMMATION

Early release of high-mobility group box 1 (HMGB1) from neurons in experimental subarachnoid hemorrhage in vivo and in vitro

(2014) Qing Sun et al.   Journal of Neuroinflammation

Protective Effect of Glycyrrhizin, a Direct HMGB1 Inhibitor, on Focal Cerebral Ischemia/Reperfusion-Induced Inflammation, Oxidative Stress, and Apoptosis in Rats

(2014) Gu Gong et al.   PLoS One

Traumatic axonal injury in the mouse is accompanied by a dynamic inflammatory response, astroglial reactivity and complex behavioral changes

(2013) Sara Ekmark-Lewén et al.   Journal of Neuroinflammation

Anti-high mobility group box-1 antibody therapy for traumatic brain injury

(2012) Yu Okuma et al.   ANNALS OF NEUROLOGY

High Mobility Group Box 1/Toll-like Receptor Danger Signaling Increases Brain Neuroimmune Activation in Alcohol Dependence

(2012) Fulton T. Crews et al.   BIOLOGICAL PSYCHIATRY

High expression of STIM1 in the early stages of diffuse axonal injury

(2012) Yu Li et al.   BRAIN RESEARCH

Danger Signals Activating the Immune Response after Trauma

(2012) Stefanie Hirsiger et al.   MEDIATORS OF INFLAMMATION

Intranasal Delivery of HMGB1 siRNA Confers Target Gene Knockdown and Robust Neuroprotection in the Postischemic Brain

(2012) Il-Doo Kim et al.   MOLECULAR THERAPY

Glycyrrhizic acid affords robust neuroprotection in the postischemic brain via anti-inflammatory effect by inhibiting HMGB1 phosphorylation and secretion

(2012) Seung-Woo Kim et al.   NEUROBIOLOGY OF DISEASE

Elevation of High-Mobility Group Protein Box-1 in Serum Correlates with Severity of Acute Intracerebral Hemorrhage

(2010) Yu Zhou et al.   MEDIATORS OF INFLAMMATION

Blood–brain barrier breakdown as a therapeutic target in traumatic brain injury

(2010) Dan Shlosberg et al.   Nature Reviews Neurology

High-Mobility Group Box 1 Promotes Metalloproteinase-9 Upregulation Through Toll-Like Receptor 4 After Cerebral Ischemia

(2010) Jianhua Qiu et al.   STROKE

Subarachnoid Hemorrhage Induces Gliosis and Increased Expression of the Pro-inflammatory Cytokine High Mobility Group Box 1 Protein

(2010) Kentaro Murakami et al.   Translational Stroke Research

Diffuse axonal injury: Novel insights into detection and treatment

(2009) Xue-Yuan Li et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Experimental models of traumatic axonal injury

(2009) Hong-Cai Wang et al.   JOURNAL OF CLINICAL NEUROSCIENCE

ROLE OF TOLL-LIKE RECEPTORS 2 AND 4, AND THE RECEPTOR FOR ADVANCED GLYCATION END PRODUCTS IN HIGH-MOBILITY GROUP BOX 1-INDUCED INFLAMMATION IN VIVO

(2009) Marieke A.D. van Zoelen et al.   SHOCK

MMPs initiate Schwann cell-mediated MBP degradation and mechanical nociception after nerve damage

(2008) Hideo Kobayashi et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Induction and subcellular localization of high-mobility group box–1 (HMGB1) in the postischemic rat brain

(2007) Jung-Bin Kim et al.   JOURNAL OF NEUROSCIENCE RESEARCH