An Antibody-Dependent Cellular Cytotoxicity Assay for Detecting Ocrelizumab Neutralizing Antibody

A competitive ligand-binding assay to detect neutralizing antibodies to a bispecific drug using a multiplex Meso Scale Discovery platform

(2021) Vitaly Ablamunits et al.   Bioanalysis

Thaw-and-use target cells pre-labeled with calcein AM for antibody-dependent cell-mediated cytotoxicity assays

(2017) Shan Chung et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Strategies to Determine Assay Format for the Assessment of Neutralizing Antibody Responses to Biotherapeutics

(2016) Bonnie Wu et al.   AAPS Journal

A novel method for evaluating antibody-dependent cell-mediated cytotoxicity by flowcytometry using cryopreserved human peripheral blood mononuclear cells

(2016) Makiko Yamashita et al.   Scientific Reports

A Neutralizing Antibody Assay Based on a Reporter of Antibody-Dependent Cell-Mediated Cytotoxicity

(2015) Yuling Wu et al.   AAPS Journal

Update on the Autoimmune Pathology of Multiple Sclerosis: B-Cells as Disease-Drivers and Therapeutic Targets

(2015) H.-Christian von Büdingen et al.   EUROPEAN NEUROLOGY

Development of a robust reporter-based ADCC assay with frozen, thaw-and-use cells to measure Fc effector function of therapeutic antibodies

(2014) Zhijie Jey Cheng et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Recommendations for the validation of cell-based assays used for the detection of neutralizing antibody immune responses elicited against biological therapeutics

(2011) Shalini Gupta et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Development of a quantitative, cell-line based assay to measure ADCC activity mediated by therapeutic antibodies

(2011) Alfred Schnueriger et al.   MOLECULAR IMMUNOLOGY

CD20-Targeted Therapy: The Next Generation of Antibodies

(2010) Tom van Meerten et al.   SEMINARS IN HEMATOLOGY

Ocrelizumab: a step forward in the evolution of B-cell therapy

(2009) Fariha Kausar et al.   EXPERT OPINION ON BIOLOGICAL THERAPY