Protocol to determine antibody affinity and concentration in complex solutions using microfluidic antibody affinity profiling

Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large European metropolitan region

(2023) Marc Emmenegger et al.   iScience

Avidity in antibody effector functions and biotherapeutic drug design

(2022) Simone C. Oostindie et al.   NATURE REVIEWS DRUG DISCOVERY

Both COVID-19 infection and vaccination induce high-affinity cross-clade responses to SARS-CoV-2 variants

(2022) Marc Emmenegger et al.   iScience

Serological fingerprints link antiviral activity of therapeutic antibodies to affinity and concentration

(2022) Sebastian Fiedler et al.   Scientific Reports

Antibody Affinity Governs the Inhibition of SARS-CoV-2 Spike/ACE2 Binding in Patient Serum

(2021) Sebastian Fiedler et al.   ACS Infectious Diseases

LAG3 is not expressed in human and murine neurons and does not modulate α‐synucleinopathies

(2021) Marc Emmenegger et al.   EMBO Molecular Medicine

Progress and challenges in mass spectrometry-based analysis of antibody repertoires

(2021) Igor Snapkov et al.   TRENDS IN BIOTECHNOLOGY

Anti-prothrombin autoantibodies enriched after infection with SARS-CoV-2 and influenced by strength of antibody response against SARS-CoV-2 proteins

(2021) Marc Emmenegger et al.   PLoS Pathogens

Microfluidic characterisation reveals broad range of SARS-CoV-2 antibody affinity in human plasma

(2021) Matthias M Schneider et al.   Life Science Alliance

Kinetic fingerprints differentiate the mechanisms of action of anti-Aβ antibodies

(2020) Sara Linse et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Antibody responses to viral infections: a structural perspective across three different enveloped viruses

(2019) Charles D. Murin et al.   Nature Microbiology

High-Throughput Mapping of B Cell Receptor Sequences to Antigen Specificity

(2019) Ian Setliff et al.   CELL

Microfluidic Diffusion Analysis of the Sizes and Interactions of Proteins under Native Solution Conditions

(2015) Paolo Arosio et al.   ACS Nano

Latent analysis of unmodified biomolecules and their complexes in solution with attomole detection sensitivity

(2015) Emma V. Yates et al.   Nature Chemistry

Practical guidelines for B-cell receptor repertoire sequencing analysis

(2015) Gur Yaari et al.   Genome Medicine

Molecular deconvolution of the monoclonal antibodies that comprise the polyclonal serum response

(2013) Y. Wine et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Dissection of Antibody Responses against Pneumococcal Surface Protein A: Evidence for Diverse DH-Less Heavy Chain Gene Usage and Avidity Maturation

(2009) S. Rohatgi et al.   JOURNAL OF IMMUNOLOGY