A dendritic β-galactosidase-responsive folate–monomethylauristatin E conjugate

Current ADC Linker Chemistry

(2015) Nareshkumar Jain et al.   PHARMACEUTICAL RESEARCH

Antibody-Drug Conjugates: An Emerging Concept in Cancer Therapy

(2014) Ravi V. J. Chari et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ado-trastuzumab Emtansine (T-DM1): An Antibody–Drug Conjugate (ADC) for HER2-Positive Breast Cancer

(2014) John M. Lambert et al.   JOURNAL OF MEDICINAL CHEMISTRY

Design of Self-Immolative Linkers for Tumour-Activated Prodrug Therapy

(2013) I. Tranoy-Opalinski et al.   Anti-Cancer Agents in Medicinal Chemistry

PRECEDENT: A Randomized Phase II Trial Comparing Vintafolide (EC145) and Pegylated Liposomal Doxorubicin (PLD) in Combination Versus PLD Alone in Patients With Platinum-Resistant Ovarian Cancer

(2013) R. Wendel Naumann et al.   JOURNAL OF CLINICAL ONCOLOGY

A galactosidase-responsive doxorubicin-folate conjugate for selective targeting of acute myelogenous leukemia blasts

(2013) Jonathan Clarhaut et al.   LEUKEMIA RESEARCH

An enzyme-responsive system programmed for the double release of bioactive molecules through an intracellular chemical amplification process

(2013) Marion Grinda et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

The First Generation of β-Galactosidase-Responsive Prodrugs Designed for the Selective Treatment of Solid Tumors in Prodrug Monotherapy

(2012) Thibaut Legigan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Engineering Folate–Drug Conjugates to Target Cancer: From Chemistry to Clinic

(2012) Iontcho R. Vlahov et al.   BIOCONJUGATE CHEMISTRY

Induction of β-Glucuronidase Release by Cytostatic Agents in Small Tumors

(2012) Inês F. Antunes et al.   MOLECULAR PHARMACEUTICS

A Heterodimeric Glucuronide Prodrug for Cancer Tritherapy: the Double Role of the Chemical Amplifier

(2011) Marion Grinda et al.   ChemMedChem

A Galactosidase-Responsive “Trojan Horse” for the Selective Targeting of Folate Receptor-Positive Tumor Cells

(2011) Mickaël Thomas et al.   ChemMedChem

A self-immolative dendritic glucuronide prodrug of doxorubicin

(2011) Marion Grinda et al.   MedChemComm