The design of a spiro-pyrrolidine organocatalyst and its application to catalytic asymmetric Michael addition for the construction of all-carbon quaternary centers

A General, Scalable, Organocatalytic Nitro-Michael Addition to Enones: Enantioselective Access to All-Carbon Quaternary Stereocenters

(2015) Xiaodong Gu et al.   ORGANIC LETTERS

A Multicomponent Ni-, Zr-, and Cu-Catalyzed Strategy for Enantioselective Synthesis of Alkenyl-Substituted Quaternary Carbons

(2014) Kevin P. McGrath et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diphenylprolinol Silyl Ether Catalyzed Asymmetric Michael Reaction of Nitroalkanes and β,β-Disubstituted α,β-Unsaturated Aldehydes for the Construction of All-Carbon Quaternary Stereogenic Centers

(2014) Yujiro Hayashi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Asymmetric Organocatalyzed Michael Addition of Nitromethane to a 2-Oxoindoline-3-ylidene Acetaldehyde and the Three One-Pot Sequential Synthesis of (−)-Horsfiline and (−)-Coerulescine

(2014) Takasuke Mukaiyama et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Synthetic Approach for Constructing the 3/6/6/5-Fused Tetracyclic Skeleton of Tenuipesine A

(2014) Jin-Miao Tian et al.   Chemistry-An Asian Journal

Synthesis of Tunable Diamine Ligands with Spiro Indane-2,2′-pyrrolidine Backbone and Their Applications in Enantioselective Henry Reaction

(2014) Rafał Ćwiek et al.   JOURNAL OF ORGANIC CHEMISTRY

All-Carbon Quaternary Stereogenic Centers in Acyclic Systems through the Creation of Several C–C Bonds per Chemical Step

(2014) Ilan Marek et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Exploring the Activation Modes of a Rotaxane-Based Switchable Organocatalyst

(2014) Victor Blanco et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective construction of remote quaternary stereocentres

(2014) Tian-Sheng Mei et al.   NATURE

Asymmetric Catalytic Conjugate Addition of Acetaldehyde to Nitrodienynes/Nitroenynes: Applications to the Syntheses of (+)-α-Lycorane and Chiral β-Alkynyl Acids

(2014) Xue-Ling Meng et al.   ORGANIC LETTERS

Efficient and Highly Enantioselective Construction of Trifluoromethylated Quaternary Stereogenic Centers via High-Pressure Mediated Organocatalytic Conjugate Addition of Nitromethane to β,β-Disubstituted Enones

(2014) Piotr Kwiatkowski et al.   ORGANIC LETTERS

Enantioselective Synthesis of Quaternary Carbon Stereogenic Centers through Copper-Catalyzed Conjugate Additions of Aryl- and Alkylaluminum Reagents to Acyclic Trisubstituted Enones

(2013) Jennifer A. Dabrowski et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Efficient Access to Trifluoromethyl Diarylpyrrolines and their N-Oxides through Enantioselective Conjugate Addition of Nitromethane to β,β-Disubstituted Enones

(2013) Hiroyuki Kawai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Divergent and Efficient Syntheses of theLycopodiumAlkaloids (−)-Lycojaponicumin C, (−)-8-Deoxyserratinine, (+)-Fawcettimine, and (+)-Fawcettidine

(2013) Si-Hua Hou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Formation of Quaternary Centers by Copper-Catalyzed Asymmetric Conjugate Addition of Alkylzirconium Reagents

(2013) Mireia Sidera et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic C–C Bond-Forming Multi-Component Cascade or Domino Reactions: Pushing the Boundaries of Complexity in Asymmetric Organocatalysis

(2013) Chandra M. R. Volla et al.   CHEMICAL REVIEWS

Metal-Free Enantioselective Hydroxyamination of Aldehydes with Nitrosocarbonyl Compounds Catalyzed by an Axially Chiral Amine

(2013) Taichi Kano et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Insertion of Diazoesters into Aryl-CHO Bonds: Highly Enantioselective Construction of Chiral All-Carbon Quaternary Centers

(2013) Lizhu Gao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanism and Enantioselectivity in Palladium-Catalyzed Conjugate Addition of Arylboronic Acids to β-Substituted Cyclic Enones: Insights from Computation and Experiment

(2013) Jeffrey C. Holder et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Michael Addition of Indoles to Isatylidene-3-acetaldehydes: Application to the Formal Total Synthesis of (−)-Chimonanthine

(2013) Renrong Liu et al.   ORGANIC LETTERS

Aminocatalytic Asymmetric Diels–Alder Reactions via HOMO Activation

(2012) Jun-Long Li et al.   ACCOUNTS OF CHEMICAL RESEARCH

Aromatic Spiroketal Bisphosphine Ligands: Palladium-Catalyzed Asymmetric Allylic Amination of Racemic Morita-Baylis-Hillman Adducts

(2012) Xiaoming Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Construction of an All-Carbon Quaternary Stereocenter by the Peptide-Catalyzed Asymmetric Michael Addition of Nitromethane to β-Disubstituted α,β-Unsaturated Aldehydes

(2012) Kengo Akagawa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Effect of Multinuclear Copper/Aluminum Complexes in Highly Asymmetric Conjugate Addition of Trimethylaluminum to Acyclic Enones

(2012) Kohei Endo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cinchona-based Primary Amine Catalysis in the Asymmetric Functionalization of Carbonyl Compounds

(2012) Paolo Melchiorre   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Michael Addition of N-Boc-Protected Oxindoles to Nitroalkenes Catalyzed by a Chiral Secondary Amine

(2012) Chuan Wang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Formal Synthesis of (−)-Cephalotaxine Based on a Tandem Hydroamination/Semipinacol Rearrangement Reaction

(2012) Qing-Wei Zhang et al.   Chemistry-An Asian Journal

The Diarylprolinol Silyl Ether System: A General Organocatalyst

(2011) Kim L. Jensen et al.   ACCOUNTS OF CHEMICAL RESEARCH

Enantioselective synthesis of all-carbon quaternary stereogenic centers in acyclic systems

(2011) Jaya Prakash Das et al.   CHEMICAL COMMUNICATIONS

Semipinacol Rearrangement in Natural Product Synthesis

(2011) Zhen-Lei Song et al.   CHEMICAL REVIEWS

Total Synthesis of (±)-Maistemonine, (±)-Stemonamide, and (±)-Isomaistemonine

(2011) Zhi-Hua Chen et al.   JOURNAL OF ORGANIC CHEMISTRY

Effect of High Pressure on the Organocatalytic Asymmetric Michael Reaction: Highly Enantioselective Synthesis of γ-Nitroketones with Quaternary Stereogenic Centers

(2011) Piotr Kwiatkowski et al.   ORGANIC LETTERS

Rhodium-Catalyzed Asymmetric 1,4-Addition of Aryl Alanes to Trisubstituted Enones: Binap as an Effective Ligand in the Formation of Quaternary Stereocenters

(2010) Christine Hawner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Tetrafluorobenzobarrelenes as Effective Ligands for Rhodium-Catalyzed Asymmetric 1,4-Addition of Arylboroxines to β,β-Disubstituted α,β-Unsaturated Ketones

(2010) Ryo Shintani et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metal-catalyzed asymmetric conjugate addition reaction: formation of quaternary stereocenters

(2010) Christine Hawner et al.   CHEMICAL COMMUNICATIONS

Mechanisms in aminocatalysis

(2010) Martin Nielsen et al.   CHEMICAL COMMUNICATIONS

Catalytic Enantioselective Construction of β-Quaternary Carbons via a Conjugate Addition of Cyanide to β,β-Disubstituted α,β-Unsaturated Carbonyl Compounds

(2010) Yuta Tanaka et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Formal Syntheses of (±)-Stemonamine and (±)-Cephalotaxine

(2009) Yu-Ming Zhao et al.   JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Aminocatalysis-Gold Rush in Organic Chemistry

(2008) Paolo Melchiorre et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric multifunctional organocatalytic Michael addition of nitroalkanes to α,β-unsaturated ketones

(2008) Pengfei Li et al.   CHEMICAL COMMUNICATIONS

Modular Spiro Bidentate Nitrogen Ligands - Synthesis, Resolution and Application in Asymmetric Catalysis

(2008) Xavier Sala et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

C2Symmetric Chiral NHC Ligand for Asymmetric Quaternary Carbon Constructing Copper-Catalyzed Conjugate Addition of Grignard Reagents to 3-Substituted Cyclohexenones

(2008) Yasumasa Matsumoto et al.   JOURNAL OF ORGANIC CHEMISTRY