A mild TCEP-based para-azidobenzyl cleavage strategy to transform reversible cysteine thiol labelling reagents into irreversible conjugates

Cysteine-Selective Reactions for Antibody Conjugation

(2014) Pedro M. S. D. Cal et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Antibody-Drug Conjugates: An Emerging Concept in Cancer Therapy

(2014) Ravi V. J. Chari et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mild Method for Succinimide Hydrolysis on ADCs: Impact on ADC Potency, Stability, Exposure, and Efficacy

(2014) L. Nathan Tumey et al.   BIOCONJUGATE CHEMISTRY

Sulfhydryl-Based Tumor Antigen-Carrier Protein Conjugates Stimulate Superior Antitumor Immunity against B Cell Lymphomas

(2014) D. J. Betting et al.   JOURNAL OF IMMUNOLOGY

Self-hydrolyzing maleimides improve the stability and pharmacological properties of antibody-drug conjugates

(2014) Robert P Lyon et al.   NATURE BIOTECHNOLOGY

Selective chemical protein modification

(2014) Christopher D. Spicer et al.   Nature Communications

Reversible protein affinity-labelling using bromomaleimide-based reagents

(2013) Ramiz I. Nathani et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates

(2012) Ben-Quan Shen et al.   NATURE BIOTECHNOLOGY

Tunable reagents for multi-functional bioconjugation: reversible or permanent chemical modification of proteins and peptides by control of maleimide hydrolysis

(2011) Chris P. Ryan et al.   CHEMICAL COMMUNICATIONS

Bromopyridazinedione-mediated protein and peptide bioconjugation

(2011) Vijay Chudasama et al.   CHEMICAL COMMUNICATIONS

PEGylation of therapeutic proteins

(2010) Simona Jevševar et al.   Biotechnology Journal

Chemically modified antibodies as diagnostic imaging agents

(2010) Jeffrey J Day et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Protein Modification, Bioconjugation, and Disulfide Bridging Using Bromomaleimides

(2010) Mark E. B. Smith et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemical Modification of Proteins at Cysteine: Opportunities in Chemistry and Biology

(2009) Justin M. Chalker et al.   Chemistry-An Asian Journal

Site-Selective Glycosylation of Hemoglobin on Cys β93

(2008) Yalong Zhang et al.   BIOCONJUGATE CHEMISTRY

Chemoselective modification of proteins: hitting the target

(2008) Isaac S. Carrico   CHEMICAL SOCIETY REVIEWS

A Glycoconjugate Antigen Based on the Recognition Motif of a Broadly Neutralizing Human Immunodeficiency Virus Antibody, 2G12, Is Immunogenic but Elicits Antibodies Unable To Bind to the Self Glycans of gp120

(2008) R. D. Astronomo et al.   JOURNAL OF VIROLOGY