Journal
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
Volume 67, Issue -, Pages 461-467Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.msec.2016.05.069
Keywords
Selective laser melting; CoCrCu alloys; Antimicrobial; Antibiofilm; Coping metal
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Funding
- National Natural Science Foundation [51171186, 81301329]
- National Basic Research Program of China [2012CB619101]
- Youth Innovation Promotion Association, CAS [2014168]
- UK Royal Academy of Engineering [1213RECI052]
- EPSRC [EP/N034368/1, EP/D07942X/1] Funding Source: UKRI
- Engineering and Physical Sciences Research Council [EP/D07942X/1, EP/N034368/1] Funding Source: researchfish
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Objective: The aim of this study was to fabricate a novel coping metal CoCrCu alloy using a selective laser melting (SLM) technique with antimicrobial and antibiofilm activities and to investigate its microstructure, mechanical properties, corrosion resistance and biocompatibility. Methods: Novel CoCrCu alloy was fabricated using SLM from a mixture of commercial CoCr based alloy and elemental Cu powders. SLM CoCr without Cu served as control. Antibacterial activity was analyzed using standard antimicrobial tests, and antibiofilm properties were investigated using confocal laser scanning microscope. Cu distribution and microstructure were determined using scanning electron microscope, optical microscopy and X-ray diffraction. Corrosion resistance was evaluated by potential dynamic polarization and biocompatibility measured using an MU assay. Results: SLM CoCrCu alloys were found to be bactericidal and able to inhibit biofilm formation. Other factors such as microstructure, mechanical properties, corrosion resistance and biocompatibility were similar to those of SLM CoCr alloys. Significance: The addition of appropriate amounts of Cu not only maintains normal beneficial properties of CoCr based alloys, but also provides SLM CoCrCu alloys with excellent antibacterial and antibiofilm capabilities. This material has the potential to be used as a coping metal for dental applications. (C) 2016 Elsevier B.V. All rights reserved.
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