Design and Biological Evaluation of Furan/Pyrrole/Thiophene-2-carboxamide Derivatives as Efficient DNA GyraseB Inhibitors ofStaphylococcus aureus

Structure-guided design and development of novel benzimidazole class of compounds targeting DNA gyraseB enzyme of Staphylococcus aureus

(2014) Renuka Janupally et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design, synthesis, biological evaluation of substituted benzofurans as DNA gyraseB inhibitors of Mycobacterium tuberculosis

(2014) Janupally Renuka et al.   BIOORGANIC & MEDICINAL CHEMISTRY

1,4-Disubstituted Thiosemicarbazide Derivatives are Potent Inhibitors of Toxoplasma gondii Proliferation

(2014) Katarzyna Dzitko et al.   MOLECULES

In silico discovery and biophysical evaluation of novel 5-(2-hydroxybenzylidene) rhodanine inhibitors of DNA gyrase B

(2012) Matjaž Brvar et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE), Part II: Development of inhibitors with broad spectrum, Gram-negative antibacterial activity

(2012) Micheal Trzoss et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Structure-Based Discovery of Substituted 4,5′-Bithiazoles as Novel DNA Gyrase Inhibitors

(2012) Matjaž Brvar et al.   JOURNAL OF MEDICINAL CHEMISTRY

Pyrrolamide DNA gyrase inhibitors: Optimization of antibacterial activity and efficacy

(2011) Brian A. Sherer et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Discovery of pyrazolthiazoles as novel and potent inhibitors of bacterial gyrase

(2010) Steven M. Ronkin et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Biofilm formation by Scottish clinical isolates of Staphylococcus aureus

(2008) K. Smith et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Evaluation of zebrafish embryos as a model for assessing inhibition of hERG

(2007) S.W. Mittelstadt et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS