Synthesis of 5,6-dihydro-4H-benzo[d]isoxazol-7-one and 5,6-dihydro-4H-isoxazolo[5,4-c]pyridin-7-one Derivatives as Potential Hsp90 Inhibitors

Design, synthesis and biological activity of piperlongumine derivatives as selective anticancer agents

(2014) Yuelin Wu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

4,5,6,7-Tetrahydro-isoxazolo-[4,5-c]-pyridines as a new class of cytotoxic Hsp90 inhibitors

(2014) Riccardo Baruchello et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Evaluation of New Hsp90 Inhibitors Based on a 1,4,5-Trisubstituted 1,2,3-Triazole Scaffold

(2014) Maurizio Taddei et al.   JOURNAL OF MEDICINAL CHEMISTRY

Progress in the Discovery and Development of Heat Shock Protein 90 (Hsp90) Inhibitors

(2014) Rohit Bhat et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antiprotozoal activity of dicationic 3,5-diphenylisoxazoles, their prodrugs and aza-analogues

(2013) Donald A. Patrick et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Hsp90 Molecular Chaperone Inhibitors: Are We There Yet?

(2012) L. Neckers et al.   CLINICAL CANCER RESEARCH

Isoxazolo(aza)naphthoquinones: A new class of cytotoxic Hsp90 inhibitors

(2012) Alberto Bargiotti et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Geldanamycin and its derivatives as Hsp90 inhibitors

(2012) Magdalena Gorska   Frontiers in Bioscience-Landmark

Natural and semisynthetic azaphilones as a new scaffold for Hsp90 inhibitors

(2010) Loana Musso et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Discovery of (2,4-Dihydroxy-5-isopropylphenyl)-[5-(4-methylpiperazin-1-ylmethyl)-1,3-dihydroisoindol-2-yl]methanone (AT13387), a Novel Inhibitor of the Molecular Chaperone Hsp90 by Fragment Based Drug Design

(2010) Andrew J. Woodhead et al.   JOURNAL OF MEDICINAL CHEMISTRY

Fragment-Based Drug Discovery Applied to Hsp90. Discovery of Two Lead Series with High Ligand Efficiency

(2010) Christopher W. Murray et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of Novel 2-Aminobenzamide Inhibitors of Heat Shock Protein 90 as Potent, Selective and Orally Active Antitumor Agents

(2009) Kenneth H. Huang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Dihydroxyphenylisoindoline Amides as Orally Bioavailable Inhibitors of the Heat Shock Protein 90 (Hsp90) Molecular Chaperone

(2009) Pei-Pei Kung et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of Benzisoxazoles as Potent Inhibitors of Chaperone Heat Shock Protein 90

(2008) Ariamala Gopalsamy et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of 4,6-dimethyl-tetrahydro- and hexahydro-dibenzothiophene

(2008) Yinyong Sun et al.   TETRAHEDRON LETTERS

4,5-Diarylisoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents for the Treatment of Cancer

(2007) Paul A. Brough et al.   JOURNAL OF MEDICINAL CHEMISTRY