Isoenzyme- and Allozyme-Specific Inhibitors: 2,2′-Dihydroxybenzophenones and Their Carbonyl N-Analogues that Discriminate between Human Glutathione Transferase A1-1 and P1-1 Allozymes

2,2′-Dihydroxybenzophenones and their carbonyl N-analogues as inhibitor scaffolds for MDR-involved human glutathione transferase isoenzyme A1-1

(2014) Fereniki D. Perperopoulou et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichments

(2013) G. Madhavi Sastry et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Effect of human glutathione S-transferase hGSTP1-1 polymorphism on the detoxification of reactive metabolites of clozapine, diclofenac and acetaminophen

(2013) Sanja Dragovic et al.   TOXICOLOGY LETTERS

Xanthones in Heterocyclic Synthesis. An Efficient Route for the Synthesis of C-3 o-Hydroxyaryl Substituted 1,2-Benzisoxazoles and Their N-Oxides, Potential Scaffolds for Angiotensin(II) Antagonist Hybrid Peptides

(2011) Petros G. Tsoungas et al.   HETEROCYCLES

Xanthones in Heterocyclic Synthesis. An Efficient and General Route for the Synthesis of Regioselectively Substituted Phthalazines

(2011) Petros G. Tsoungas et al.   HETEROCYCLES

Characterization of New Potential Anticancer Drugs Designed To Overcome Glutathione Transferase Mediated Resistance

(2011) Katarina Johansson et al.   MOLECULAR PHARMACEUTICS

Glutathione transferases and development of new principles to overcome drug resistance

(2010) Andrea Sau et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Conformer Generation with OMEGA: Algorithm and Validation Using High Quality Structures from the Protein Databank and Cambridge Structural Database

(2010) Paul C. D. Hawkins et al.   Journal of Chemical Information and Modeling

Phase 1 multicenter dose-escalation study of ezatiostat hydrochloride (TLK199 tablets), a novel glutathione analog prodrug, in patients with myelodysplastic syndrome

(2009) A. Raza et al.   BLOOD

Polyisoprenylated Benzophenones from Clusiaceae: Potential Drugs and Lead Compounds

(2009) Ulyana Acuna et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Xanthone in synthesis: a reactivity profile via directed lithiation of its dimethyl ketal

(2009) Michal R. Odrowaz-Sypniewski et al.   TETRAHEDRON LETTERS

Naphthylphenstatins as tubulin ligands: Synthesis and biological evaluation

(2008) Concepción Álvarez et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Polymorphisms of drug-metabolizing enzymes (GST, CYP2B6 and CYP3A) affect the pharmacokinetics of thiotepa and tepa

(2008) Corine Ekhart et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

The Anti-cancer Drug Chlorambucil as a Substrate for the Human Polymorphic Enzyme Glutathione Transferase P1-1: Kinetic Properties and Crystallographic Characterisation of Allelic Variants

(2008) Lorien J. Parker et al.   JOURNAL OF MOLECULAR BIOLOGY