Synthesis and Evaluation of a CBZ-AAN-Dox Prodrug and itsin vitroEffects on SiHa Cervical Cancer Cells Under Hypoxic Conditions

Transcriptional regulation of the legumain gene by p53 in HCT116 cells

(2013) Takuya Yamane et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Effects of legumain as a potential prognostic factor on gastric cancers

(2013) Na Li et al.   MEDICAL ONCOLOGY

Nuclear Legumain Activity in Colorectal Cancer

(2013) Mads H. Haugen et al.   PLoS One

Hydrazinocurcumin Encapsuled Nanoparticles “Re-Educate” Tumor-Associated Macrophages and Exhibit Anti-Tumor Effects on Breast Cancer Following STAT3 Suppression

(2013) Xiwen Zhang et al.   PLoS One

Alginic Acid-Coated Chitosan Nanoparticles Loaded with Legumain DNA Vaccine: Effect against Breast Cancer in Mice

(2013) Ze Liu et al.   PLoS One

IMD-0354 Targets Breast Cancer Stem Cells: A Novel Approach for an Adjuvant to Chemotherapy to Prevent Multidrug Resistance in a Murine Model

(2013) Azucena Gomez-Cabrero et al.   PLoS One

Legumain: A biomarker for diagnosis and prognosis of human ovarian cancer

(2012) Lina Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Functional Imaging of Legumain in Cancer Using a New Quenched Activity-Based Probe

(2012) Laura E. Edgington et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Association of legumain expression pattern with prostate cancer invasiveness and aggressiveness

(2012) Yoshio Ohno et al.   WORLD JOURNAL OF UROLOGY

Targeting Cell Surface Alpha(v)beta(3) Integrin Increases Therapeutic Efficacies of a Legumain Protease-Activated Auristatin Prodrug

(2011) Yuan Liu et al.   MOLECULAR PHARMACEUTICS

Cystatin E/M suppresses legumain activity and invasion of human melanoma

(2010) Jon J Briggs et al.   BMC CANCER

A Novel Antitumor Prodrug Platform Designed to Be Cleaved by the Endoprotease Legumain

(2009) Liron Stern et al.   BIOCONJUGATE CHEMISTRY

Oral DNA vaccines target the tumor vasculature and microenvironment and suppress tumor growth and metastasis

(2008) Rong Xiang et al.   IMMUNOLOGICAL REVIEWS