Article
Polymer Science
Henry L. Cater, Iana Balynska, Marshall J. Allen, Benny D. Freeman, Zachariah A. Page
Summary: This paper presents a systematic study on ROMP with endo-norbornene monomers using stable chelated Ru-alkylidene initiators. The study shows that ROMP with endo-norbornene monomers is versatile and robust, providing access to polymers with excellent molecular weight control, low dispersities, good functional group tolerance, and high chain-end fidelity. The process is oxygen-tolerant and can be performed under ambient conditions, allowing for the synthesis of mechanically robust thermoplastics with high glass transition and decomposition temperatures.
Article
Polymer Science
Yuya Watanabe, Riki Kato, Kazuki Fukushima, Takashi Kato
Summary: Aromatic ester triad mesogens are incorporated into biodegradable aliphatic polycarbonate sequences to enhance their physical properties while maintaining degradability.
Article
Materials Science, Characterization & Testing
Remilson Cruz, Muhammad Nisar, Humberto Palza, Mehrdad Yazdani-Pedram, Hector Aguilar-Bolados, Raul Quijada
Summary: The use of biodegradable polymers to reduce environmental pollution has become a popular topic of research. This study synthesized graphene oxide (GO) nanoparticles functionalized with alkylamines and used them as fillers in PLA nanocomposites. The results showed that the addition of modified GO improved the barrier properties of PLA, making it suitable for food packaging applications.
Article
Chemistry, Multidisciplinary
Vajk Farkas, Marton Nagyhazi, Paul T. Anastas, Juergen Klankermayer, Robert Tuba
Summary: Addressing the challenge of plastic waste requires diverse strategies and technologies. This article focuses on the development of new catalytic processes to convert polyethylene waste into propylene, which can be used to produce biodegradable high-performance polymers. It also discusses the concept of using green propylene as a raw material for compostable polymers.
Review
Engineering, Biomedical
Taravat Khodaei, Elizabeth Schmitzer, Abhirami P. Suresh, Abhinav P. Acharya
Summary: The immune responses to degradable alloy implants are not well understood and further research is needed. This article reviews recent reports on the role of immune cells in inducing immune responses against degradable implants and discusses the differences in immune response between non-degradable and degradable implants.
BIOACTIVE MATERIALS
(2023)
Article
Acoustics
R. Sailesh, L. Yuvaraj, Jeyaraj Pitchaimani, Mrityunjay Doddamani, Lenin Babu Mailan Chinnapandi
Summary: The research presents the influence of perforations with arbitrarily varying cross-sections on the acoustic behavior of 3D printed bio-degradable panels made of Poly Lactic Acid (PLA). Results show that perforated panels with varying cross-sections exhibit better sound absorption compared to uniform cross-sectional perforations, with DC and D perforation patterns showing comparable and lower transmission losses. Geometrical perforation variations are crucial in designing soundproof panels, as demonstrated in the study, and numerical analysis provides guidelines for designing optimum perforation geometries.
Article
Nanoscience & Nanotechnology
Junlong Huang, Guangzhong Xie, Qikun Wei, Yuanjie Su, Xiangdong Xu, Yadong Jiang
Summary: This study developed a degradable MXene-polylactic acid textile with good sensitivity, response time, and mechanical stability. The material exhibited efficient degradation in sodium carbonate solution and demonstrated the capability to monitor various physiological activities.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Polymer Science
Huanting Li, Yuhua Yan, Xing Jiang, Jingjing Lin, Minfeng Li
Summary: This study investigates the use of non-linear analogues as toughening additives for polylactic acid (PLA) and finds that they can significantly improve the toughness of PLA without compromising its elastic modulus and yield strength.
Article
Polymer Science
Maria Psarrou, Martha Georgia Kothri, Maria Vamvakaki
Summary: A new linear copolymer based on acylhydrazone linkages was synthesized and characterized for its degradation under both acidic and photo conditions. The copolymer was chemically linked to an anticancer drug to form amphiphilic polymer-drug conjugates, which self-assembled into spherical nanoparticles for therapeutic cargo release. The assemblies were disrupted under UV light and decreased pH, releasing the drug payload.
Article
Chemistry, Multidisciplinary
Yu-Kai Su, Gabriel N. Short, Stephen A. Miller
Summary: Citric acid can form a cyclic imide when combined with a primary amine. By reacting a reduced derivative of citric acid with glycine, a cyclic imide diacid can be obtained. This monomer can be copolymerized with various diols to produce copolymers with adjustable glass transition temperature from 25 to 134°C. These polyimide-esters can hydrolyze under environmentally-relevant conditions, making them potential sustainable replacements for high Tg commodity plastics.
Article
Biochemistry & Molecular Biology
Wenlong Li, Ce Sun, Changxin Li, Yizhuo Xu, Haiyan Tan, Yanhua Zhang
Summary: Biodegradable composite films of PLA and PBAT were prepared by a co-precipitation and hot-pressing method, showing improved mechanical properties and UV barrier properties upon the addition of 4%wt PBAT. The potential for UV screening packaging applications is high due to the excellent thermal stability and satisfactory mechanical properties of the composite films.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Review
Environmental Sciences
Fatemeh Nemati, Maryam Rezaie, Hadi Tabesh, Kamel Eid, Guobao Xu, Mohammad Reza Ganjali, Morteza Hosseini, Ceren Karaman, Nevin Erk, Pau-Loke Show, Najmeh Zare, Hassan Karimi-Maleh
Summary: Graphene-based nanomaterials have shown great potential in various applications due to their remarkable properties. Functionalized graphene nanocomposites have advantages in increasing surface area and porosity, improving adsorption capacities, reducing adsorption energy barrier, and preventing agglomeration. Combining cerium structures with graphene networks has been widely investigated to enhance the properties of the composite. This research reviews the recent developments in cerium functionalized graphene derivatives and their industrial applications, providing comprehensive information on these nanonetworks. The applications of functionalized graphene derivatives are successfully summarized. This systematic review study has the potential to pave the way for scientific research in material science and various applications.
ENVIRONMENTAL RESEARCH
(2022)
Article
Multidisciplinary Sciences
Ran Yang, Xu Zhang, Binggang Chen, Qiuyan Yan, Jinghua Yin, Shifang Luan
Summary: This study proposes a method to fabricate a robust adhesive with degradable backbone (BDRA) in physiological environment. The BDRA shows good adhesion strength on diverse materials and tissues, and has enhanced tunable degradability, mechanical modulus, setting time, and biocompatibility.
NATURE COMMUNICATIONS
(2023)
Review
Biochemistry & Molecular Biology
Stephan Haudum, Paul Strasser, Ian Teasdale
Summary: Synthetic polymers are widely used in biomedical applications due to their consistent and reproducible properties, scalability, and customizable functionality. However, current synthetic polymers have limitations, especially in terms of timely biodegradation. By incorporating silicon and phosphorus into polymers, researchers aim to induce cleavability in the polymer main chain, allowing for degradation in mild biological environments. This article discusses the basic chemistry of these materials and highlights recent studies on their medical applications.
MACROMOLECULAR BIOSCIENCE
(2023)
Article
Environmental Sciences
Lemeng Wang, Zhikai Zhao, Wen Wang, Gaoshan Xing, Fang Zeng, Liqiang Qi
Summary: In this study, a novel catalyst V-Cu-Ce-ZSM-5 was explored for simultaneous removal of SO2 and NOx from flue gas, with the addition of graphene oxide (GO) to further enhance its catalytic activity. The results showed that V-Cu-Ce-ZSM-5@GO0.5 exhibited the best performance for SO2 and NOx oxidation at a low temperature of 150 degrees C.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Polymer Science
Irem Akar, Jeffrey C. Foster, Xiyue Leng, Amanda K. Pearce, Robert T. Mathers, Rachel K. O'Reilly
Summary: The development of a predictive relationship between polymer hydrophobicity and cloud point temperature is of great importance for the rational design of copolymers with desired temperature responses.
Article
Chemistry, Multidisciplinary
Jeffrey C. Foster, Adam W. Cook, Nicolas T. Monk, Brad H. Jones, Leah N. Appelhans, Erica M. Redline, Samuel C. Leguizamon
Summary: The development of selective dual-wavelength olefin metathesis polymerization enables efficient initiation and fast reaction stoppage, allowing for 2D stereolithographic printing and 3D continuous additive manufacturing at high printing speeds.
Article
Chemistry, Multidisciplinary
Yumeng Zhu, William R. Archer, Katlyn F. Morales, Michael D. Schulz, Yin Wang, John B. Matson
Summary: Inducing high levels of reactive oxygen species (ROS) in tumor cells is a cancer therapy method called chemodynamic therapy (CDT). In this study, a peptide-H2S donor conjugate complexed with Fe2+ called AAN-PTC-Fe2+ was developed. AAN tripeptide was specifically cleaved by legumain, an enzyme overexpressed in glioma cells, to release carbonyl sulfide (COS) which hydrolyzed to form H2S. Fe2+ and H2S together increased intracellular ROS levels and decreased viability in C6 glioma cells. AAN-PTC-Fe2+ performed better than temozolomide without cytotoxicity towards H9C2 cardiomyocytes. This study provides an H2S-amplified, enzyme-responsive platform for synergistic cancer treatment.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Multidisciplinary
Zhao Li, Soumil Y. Joshi, Yin Wang, Sanket A. Deshmukh, John B. Matson
Summary: We report three constitutionally isomeric tetrapeptides with different nanostructures that catalyze hydrolysis reactions. Coarse-grained molecular dynamics simulations and machine learning analysis reveal the clusters of specific amino acid residues in hydrophobic pockets along the outer edge of the most efficient nanostructure, providing insights into the observed catalytic rate enhancement. This study demonstrates how subtle molecular-level changes can influence supramolecular nanostructures and catalytic efficiency.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Review
Biochemistry & Molecular Biology
Santu Sarkar, Rajnish Kumar, John B. Matson
Summary: Gasotransmitters, including nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S), play important roles in maintaining various physiological processes. However, their clinical applications are limited due to their gaseous nature, short half-life, and broad physiological roles. Hydrogel-based delivery systems offer a potential solution for localized delivery of gasotransmitters. This review highlights the biological importance of gasotransmitters, discusses the fabrication of hydrogel materials, and explores the release behavior and potential therapeutic applications of gasotransmitter-releasing hydrogels. The authors also discuss the future of this field and the challenges that lie ahead.
MACROMOLECULAR BIOSCIENCE
(2023)
Article
Polymer Science
Samantha J. Scannelli, Anshul Paripati, Jeffrey R. Weaver, Clark Vu, Mohammed Alaboalirat, Diego Troya, John B. Matson
Summary: This study investigates the influence of different anchor groups on the activity of ROMP reaction through experiments and calculations. It is found that the HOMO energy of the anchor group is correlated with the propagation rate constant of the catalyst, indicating the significance of anchor group selection in ROMP reaction activity.
Article
Polymer Science
Samantha J. Scannelli, Mohammed Alaboalirat, Diego Troya, John B. Matson
Summary: Ring-opening metathesis polymerization (ROMP) mediated by Grubbs' third-generation catalyst (G3) is widely used to make bottlebrush polymers. This study investigated the effect of anchor groups on the livingness of ROMP, finding a positive correlation between anchor group energy levels and reaction rate constants, suggesting different degrees of livingness among the anchor groups.
Article
Multidisciplinary Sciences
Yumeng Zhu, Yulia Shmidov, Elizabeth A. Harris, Michelle H. Theus, Ronit Bitton, John B. Matson
Summary: In this research, hydrogels that imitate cryptic sites in the native extracellular matrix (ECM) were synthesized using switch peptides. The inert matrix undergoes a transformation into a bioadhesive synthetic ECM in response to enzymes on endothelial cells' surface. Cryptic sites are short signaling peptides that are hidden within the native ECM. Enzymatic cleavage of an ECM protein reveals these hidden peptide sequences, which interact with surface receptors to control cell behavior. Materials that mimic this dynamic interplay between cells and their surroundings via cryptic sites could enable application of this endogenous signaling phenomenon in synthetic ECM hydrogels.
NATURE COMMUNICATIONS
(2023)
Article
Polymer Science
Cody T. T. Bezik, Erica M. M. Redline, Jeffrey C. C. Foster, Amalie L. L. Frischknecht
Summary: This work investigates the influence of blend composition, network architecture, and hydrogen bonding on the material properties of crosslinked epoxy networks. The study finds that the introduction of hydrogen bonding significantly enhances the glass transition temperature (T(g)) of binary blend networks with lightly crosslinked systems. It also demonstrates that hydrogen bonding generally enhances Young's modulus (Y) and allows access to desirable dynamic behavior such as self-healing.
Article
Polymer Science
Jeffrey C. Foster, Joshua T. Damron, Honghai Zhang
Summary: Controlling the monomer sequence of synthetic polymers is a major challenge in polymer science. This study investigates cyclic olefin monomers for ring-opening metathesis polymerization (ROMP) and identifies easily synthesized oxanorbornene imide monomers suitable for single unit addition reactions. The findings enable the synthesis of multiblock copolymers with precise functionalization sites and singly cross-linked four-armed star copolymers.
Article
Polymer Science
Sarah N. Swilley, Evan M. Zajkowski, John B. Matson
Summary: We have developed a polymeric version of Piloty's acid that allows for tuning the release rate of HNO by adjusting the block ratios of PEG-b-poly(Piloty's acid) in a block copolymer system. By increasing the length of the poly(Piloty's acid) block, the HNO release from the block copolymers can vary by up to an order of magnitude. This study has potential implications in the development of HNO-releasing polymers for studying the effects of sustained HNO delivery in biological systems.
Article
Polymer Science
Mohammed Alaboalirat, Samantha J. Scannelli, Hadi Rahmaninejad, Jan-Michael Carrillo, Changwoo Do, John B. Matson, Rana Ashkar
Summary: Bottlebrush polymers are a unique class of macromolecular architectures with diverse applications that depend on their shape and size. This study systematically analyzed the structural and conformational properties of bottlebrush polymers using experimental and computational methods, providing key parameters and validating mean field theories.
Article
Polymer Science
Samantha J. Scannelli, Mohammed Alaboalirat, Diego Troya, John B. Matson
Summary: Norbornene-based monomers are commonly used in ring-opening metathesis polymerization (ROMP) due to their high ring strain. Recent studies have shown that the structure of norbornene derivatives significantly influences polymerization rates, with the anchor group playing a critical role.
Article
Polymer Science
Samantha J. Scannelli, Mohammed Alaboalirat, Diego Troya, John B. Matson
Summary: This study introduces a new anchor group, NBL, for ROMP and evaluates the polymerization rates of different positions of side-chain macromonomers. The results show that macromonomers with side-chains in the meta position have higher polymerization rates. Conversely, macromonomers with side-chains in the ortho position have lower polymerization rates, possibly due to steric interference.
Review
Nanoscience & Nanotechnology
Zhao Li, Yumeng Zhu, John B. Matson
Summary: Stimuli-responsive peptide-based biomaterials, particularly pH-responsive ones, have great potential in drug delivery and tissue engineering. By incorporating pH-responsive amino acids and organic linkers into peptides, they can self-assemble into various nanostructures. These biocompatible and adjustable platforms are ideal for drug release and mimicking the extracellular matrix. This review focuses on the design motifs and mechanisms of pH-responsiveness in self-assembling peptide-based biomaterials, highlighting recent advances in drug delivery and tissue engineering, and discussing future challenges and areas for development.
ACS APPLIED BIO MATERIALS
(2022)
