Development of purification processes for fully human bispecific antibodies based upon modification of protein A binding avidity

A novel, native-format bispecific antibody triggering T-cell killing of B-cells is robustly active in mouse tumor models and cynomolgus monkeys

(2015) Eric J. Smith et al.   Scientific Reports

Inactivation of viruses using novel protein A wash buffers

(2014) Glen R. Bolton et al.   BIOTECHNOLOGY PROGRESS

Development of a Human IgG4 Bispecific Antibody for Dual Targeting of Interleukin-4 (IL-4) and Interleukin-13 (IL-13) Cytokines

(2013) Christoph Spiess et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A tale of two specificities: bispecific antibodies for therapeutic and diagnostic applications

(2013) Hannah Byrne et al.   TRENDS IN BIOTECHNOLOGY

Advances in bispecific biotherapeutics for the treatment of cancer

(2012) Chad May et al.   BIOCHEMICAL PHARMACOLOGY

Dual targeting strategies with bispecific antibodies

(2012) Roland Kontermann   mAbs

Emerging antibody combinations in oncology

(2011) Stephen J. Demarest et al.   mAbs

Buy buy bispecific antibodies

(2011) David Holmes   NATURE REVIEWS DRUG DISCOVERY

Bispecific Antibodies for Cancer Immunotherapy

(2010) Dafne Müller et al.   BIODRUGS

Development of a Two-part Strategy to Identify a Therapeutic Human Bispecific Antibody That Inhibits IgE Receptor Signaling

(2010) Janet Jackman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Catumaxomab

(2010) Rolf Linke et al.   mAbs

Ligands for mixed-mode protein chromatography: Principles, characteristics and design

(2009) Guofeng Zhao et al.   JOURNAL OF BIOTECHNOLOGY

The distinctive separation attributes of mixed-mode resins and their application in monoclonal antibody downstream purification process

(2009) Jie Chen et al.   JOURNAL OF CHROMATOGRAPHY A

Host cell protein clearance during protein a chromatography: Development of an improved column wash step

(2008) Abhinav A. Shukla et al.   BIOTECHNOLOGY PROGRESS