Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin of Staphylococcus aureus for the generation of neutralizing antibodies

MEDI4893* Promotes Survival and Extends the Antibiotic Treatment Window in a Staphylococcus aureus Immunocompromised Pneumonia Model

(2015) L. Hua et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Structure-Function Analysis of Heterodimer Formation, Oligomerization, and Receptor Binding of theStaphylococcus aureusBi-component Toxin LukGH

(2014) Adriana Badarau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of Neutralization of a Human Anti-α-toxin Antibody

(2014) Vaheh Oganesyan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Five birds, one stone: Neutralization of α-hemolysin and 4 bi-component leukocidins ofStaphylococcus aureuswith a single human monoclonal antibody

(2014) Harald Rouha et al.   mAbs

The Bicomponent Pore-Forming Leucocidins of Staphylococcus aureus

(2014) Francis Alonzo et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

The staphylococcal toxins γ-haemolysin AB and CB differentially target phagocytes by employing specific chemokine receptors

(2014) András N. Spaan et al.   Nature Communications

How good are my data and what is the resolution?

(2013) Philip R. Evans et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Neutrophils Versus Staphylococcus aureus: A Biological Tug of War

(2013) András N. Spaan et al.   Annual Review of Microbiology

Staphylococcus aureus Leukotoxin ED Targets the Chemokine Receptors CXCR1 and CXCR2 to Kill Leukocytes and Promote Infection

(2013) Tamara Reyes-Robles et al.   Cell Host & Microbe

The Staphylococcal Toxin Panton-Valentine Leukocidin Targets Human C5a Receptors

(2013) András N. Spaan et al.   Cell Host & Microbe

A Serologic Correlate of Protective Immunity Against Community-Onset Staphylococcus aureus Infection

(2013) Stephanie A. Fritz et al.   CLINICAL INFECTIOUS DISEASES

Staphylococcus aureus Elaborates Leukocidin AB To Mediate Escape from within Human Neutrophils

(2013) Ashley L. DuMont et al.   INFECTION AND IMMUNITY

Children with Invasive Staphylococcus aureus Disease Exhibit a Potently Neutralizing Antibody Response to the Cytotoxin LukAB

(2013) Isaac P. Thomsen et al.   INFECTION AND IMMUNITY

Identification of a Crucial Residue Required for Staphylococcus aureus LukAB Cytotoxicity and Receptor Recognition

(2013) Ashley L. DuMont et al.   INFECTION AND IMMUNITY

The macromolecular crystallography beamline I911-3 at the MAX IV laboratory

(2013) Thomas Ursby et al.   JOURNAL OF SYNCHROTRON RADIATION

High throughput solution-based measurement of antibody-antigen affinity and epitope binning

(2013) Patricia Estep et al.   mAbs

Staphylococcus aureus LukAB cytotoxin kills human neutrophils by targeting the CD11b subunit of the integrin Mac-1

(2013) A. L. DuMont et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Addressing polyspecificity of antibodies selected from an in vitro yeast presentation system: a FACS-based, high-throughput selection and analytical tool

(2013) Y. Xu et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Anti-bacterial monoclonal antibodies: Back to the future?

(2012) Martin B. Oleksiewicz et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The potential use of toxin antibodies as a strategy for controlling acuteStaphylococcus aureusinfections

(2012) Gordon YC Cheung et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Lower Antibody Levels to Staphylococcus aureus Exotoxins Are Associated With Sepsis in Hospitalized Adults With Invasive S. aureus Infections

(2012) R. P. Adhikari et al.   JOURNAL OF INFECTIOUS DISEASES

Staphylococcus aureus Leukotoxin GH Promotes Inflammation

(2012) Natalia Malachowa et al.   JOURNAL OF INFECTIOUS DISEASES

Staphylococcus aureus Hemolysins, bi-component Leukocidins, and Cytolytic Peptides: A Redundant Arsenal of Membrane-Damaging Virulence Factors?

(2012) François Vandenesch et al.   Frontiers in Cellular and Infection Microbiology

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A simple method of markerless gene deletion in Staphylococcus aureus

(2011) Fuminori Kato et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Crystal structure of the octameric pore of staphylococcal  -hemolysin reveals the  -barrel pore formation mechanism by two components

(2011) K. Yamashita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Secretion-and-capture cell-surface display for selection of target-binding proteins

(2011) J. A. Rakestraw et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Neutrophils in innate host defense against Staphylococcus aureus infections

(2011) Kevin M. Rigby et al.   Seminars in Immunopathology

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Characterization of a new cytotoxin that contributes to Staphylococcus aureus pathogenesis

(2010) Ashley L. DuMont et al.   MOLECULAR MICROBIOLOGY

Identification of a Novel Staphylococcus aureus Two-Component Leukotoxin Using Cell Surface Proteomics

(2010) Christy L. Ventura et al.   PLoS One

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY