Cell-specific overactivation of nuclear erythroid 2 p45-related factor 2-mediated gene expression in myeloid cells decreases hepatic ischemia/reperfusion injury

Nrf2 Activation Promotes Keratinocyte Survival during Early Skin Carcinogenesis via Metabolic Alterations

(2015) F. Rolfs et al.   CANCER RESEARCH

Overactivation of the nuclear factor (erythroid-derived 2)-like 2-antioxidant response element pathway in hepatocytes decreases hepatic ischemia/reperfusion injury in mice

(2015) Lung-Yi Lee et al.   LIVER TRANSPLANTATION

Nrf2 promotes the development of fibrosis and tumorigenesis in mice with defective hepatic autophagy

(2014) Hong-Min Ni et al.   JOURNAL OF HEPATOLOGY

Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors

(2014) Elisa Gomez Perdiguero et al.   NATURE

Activation of the Nrf2-ARE Pathway in Hepatocytes Protects Against Steatosis in Nutritionally Induced Non-alcoholic Steatohepatitis in Mice

(2014) Lung-Yi Lee et al.   TOXICOLOGICAL SCIENCES

Nuclear Factor Erythroid 2–Related Factor 2 Regulates Toll-Like Receptor 4 Innate Responses in Mouse Liver Ischemia-Reperfusion Injury Through Akt-Forkhead box Protein O1 Signaling Network

(2014) Jing Huang et al.   TRANSPLANTATION

Nrf2 Activation Protects the Liver From Ischemia/Reperfusion Injury in Mice

(2013) Kazuhiro Kudoh et al.   ANNALS OF SURGERY

Activated Nrf2 impairs liver regeneration in mice by activation of genes involved in cell-cycle control and apoptosis

(2013) Ulrike A. Köhler et al.   HEPATOLOGY

KEAP1-NRF2 complex in ischemia-induced hepatocellular damage of mouse liver transplants

(2013) Bibo Ke et al.   JOURNAL OF HEPATOLOGY

Toward clinical application of the Keap1–Nrf2 pathway

(2013) Takafumi Suzuki et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Nrf2 links epidermal barrier function with antioxidant defense

(2012) Matthias Schäfer et al.   EMBO Molecular Medicine

Liver Ischemia and Reperfusion Injury: New Insights into Mechanisms of Innate-Adaptive Immune-Mediated Tissue Inflammation

(2011) Y. Zhai et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Nrf2: control of sensitivity to carcinogens

(2011) Stephen L. Slocum et al.   ARCHIVES OF TOXICOLOGY

Crosstalk of reactive oxygen species and NF-κB signaling

(2010) Michael J Morgan et al.   CELL RESEARCH

Applications of myeloid-specific promoters in transgenic mice support in vivo imaging and functional genomics but do not support the concept of distinct macrophage and dendritic cell lineages or roles in immunity

(2010) D. A. Hume   JOURNAL OF LEUKOCYTE BIOLOGY

4-Hydroxy-2-nonenal protects against cardiac ischemia–reperfusion injury via the Nrf2-dependent pathway

(2010) Yan Zhang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Enhanced expression of Nrf2 in mice attenuates the fatty liver produced by a methionine- and choline-deficient diet☆

(2010) Yu-Kun Jennifer Zhang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Oleanolic acid activates Nrf2 and protects from acetaminophen hepatotoxicity via Nrf2-dependent and Nrf2-independent processes

(2009) Scott A. Reisman et al.   BIOCHEMICAL PHARMACOLOGY

Nrf2: friend or foe for chemoprevention?

(2009) T. W. Kensler et al.   CARCINOGENESIS

Nuclear factor erythroid 2-related factor 2 is a positive regulator of human bile salt export pump expression

(2009) Jittima Weerachayaphorn et al.   HEPATOLOGY

Transcription factor Nrf2 is protective during ischemic and nephrotoxic acute kidney injury in mice

(2009) Manchang Liu et al.   KIDNEY INTERNATIONAL

CDDO-Im protects from acetaminophen hepatotoxicity through induction of Nrf2-dependent genes

(2009) Scott A. Reisman et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Regulatory potential for concerted modulation of Nrf2- and Nfkb1-mediated gene expression in inflammation and carcinogenesis

(2008) S Nair et al.   BRITISH JOURNAL OF CANCER

Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy

(2008) T. Shibata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic or Pharmacologic Amplification of Nrf2 Signaling Inhibits Acute Inflammatory Liver Injury in Mice

(2008) William O. Osburn et al.   TOXICOLOGICAL SCIENCES