Why I do not treat patients for mild disease

All-oral 12-week treatment with daclatasvir plus sofosbuvir in patients with hepatitis C virus genotype 3 infection: ALLY-3 phase III study

(2015) David R. Nelson et al.   HEPATOLOGY

Low risk of liver decompensation among human immunodeficiency virus/hepatitis C virus-coinfected patients with mild fibrosis in the short term

(2015) Juan Macías et al.   HEPATOLOGY

LP32 : Real-world effectiveness of ledipasvir/sofosbuvir 8 weeks chronic hepatitis C treatment

(2015) P. Buggisch et al.   JOURNAL OF HEPATOLOGY

LP14 : A phase 3, randomised, open-label study to evaluate the efficacy and safety of 8 and 12 weeks of simeprevir (SMV) plus sofosbuvir (SOF) in treatment-naïve and -experienced patients with chronic HCV genotype 1 infection without cirrhosis: Optimist-1

(2015) P. Kwo et al.   JOURNAL OF HEPATOLOGY

EASL Recommendations on Treatment of Hepatitis C 2015

(2015)   JOURNAL OF HEPATOLOGY

Ombitasvir plus paritaprevir plus ritonavir with or without ribavirin in treatment-naive and treatment-experienced patients with genotype 4 chronic hepatitis C virus infection (PEARL-I): a randomised, open-label trial

(2015) Christophe Hézode et al.   LANCET

Ledipasvir-sofosbuvir with or without ribavirin to treat patients with HCV genotype 1 infection and cirrhosis non-responsive to previous protease-inhibitor therapy: a randomised, double-blind, phase 2 trial (SIRIUS)

(2015) Marc Bourlière et al.   LANCET INFECTIOUS DISEASES

Ledipasvir and sofosbuvir for hepatitis C genotype 4: a proof-of-concept, single-centre, open-label phase 2a cohort study

(2015) Anita Kohli et al.   LANCET INFECTIOUS DISEASES

ABT-450, Ritonavir, Ombitasvir, and Dasabuvir Achieves 97% and 100% Sustained Virologic Response With or Without Ribavirin in Treatment-Experienced Patients With HCV Genotype 1b Infection

(2014) Pietro Andreone et al.   GASTROENTEROLOGY

Evolution of noninvasive tests of liver fibrosis is associated with prognosis in patients with chronic hepatitis C

(2014) Julien Vergniol et al.   HEPATOLOGY

Treatment of Hepatitis C

(2014) Anita Kohli et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Should we await IFN-free regimens to treat HCV genotype 1 treatment-naive patients? A cost-effectiveness analysis (ANRS 95141)

(2014) Sylvie Deuffic-Burban et al.   JOURNAL OF HEPATOLOGY

Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study

(2014) Eric Lawitz et al.   LANCET

Retreatment of HCV with ABT-450/r–Ombitasvir and Dasabuvir with Ribavirin

(2014) Stefan Zeuzem et al.   NEW ENGLAND JOURNAL OF MEDICINE

Treatment of HCV with ABT-450/r–Ombitasvir and Dasabuvir with Ribavirin

(2014) Jordan J. Feld et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ledipasvir and Sofosbuvir for Untreated HCV Genotype 1 Infection

(2014) Nezam Afdhal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ledipasvir and Sofosbuvir for Previously Treated HCV Genotype 1 Infection

(2014) Nezam Afdhal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ledipasvir and Sofosbuvir for 8 or 12 Weeks for Chronic HCV without Cirrhosis

(2014) Kris V. Kowdley et al.   NEW ENGLAND JOURNAL OF MEDICINE

ABT-450/r–Ombitasvir and Dasabuvir with or without Ribavirin for HCV

(2014) Peter Ferenci et al.   NEW ENGLAND JOURNAL OF MEDICINE

Daclatasvir plus Sofosbuvir for Previously Treated or Untreated Chronic HCV Infection

(2014) Mark S. Sulkowski et al.   NEW ENGLAND JOURNAL OF MEDICINE

Association Between Sustained Virological Response and All-Cause Mortality Among Patients With Chronic Hepatitis C and Advanced Hepatic Fibrosis

(2013) Adriaan J. van der Meer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Epidemiology and natural history of HCV infection

(2013) Behzad Hajarizadeh et al.   Nature Reviews Gastroenterology & Hepatology

Global epidemiology of hepatitis C virus infection: New estimates of age-specific antibody to HCV seroprevalence

(2012) Khayriyyah Mohd Hanafiah et al.   HEPATOLOGY

Noninvasive Tests for Fibrosis and Liver Stiffness Predict 5-Year Outcomes of Patients With Chronic Hepatitis C

(2011) Julien Vergniol et al.   GASTROENTEROLOGY

Aging of Hepatitis C Virus (HCV)-Infected Persons in the United States: A Multiple Cohort Model of HCV Prevalence and Disease Progression

(2009) Gary L. Davis et al.   GASTROENTEROLOGY

Prospective risk assessment for hepatocellular carcinoma development in patients with chronic hepatitis C by transient elastography

(2009) Ryota Masuzaki et al.   HEPATOLOGY

Liver biopsy

(2008) Don C. Rockey et al.   HEPATOLOGY