Review
Oncology
Felix M. Onyije, Ann Olsson, Dan Baaken, Friederike Erdmann, Martin Stanulla, Daniel Wollschlaeger, Joachim Schuez
Summary: Leukemia is the most common type of cancer in children worldwide. This umbrella review examines the environmental risk factors and the risk of childhood acute lymphoblastic leukemia (ALL). Only low doses of ionizing radiation in early childhood and maternal exposure to general pesticides during pregnancy showed convincing evidence of an association with childhood ALL.
Article
Public, Environmental & Occupational Health
Muhammad Waseem Khan, Jukka Juutilainen, Anssi Auvinen, Jonne Naarala, Eero Pukkala, Paivi Roivainen
Summary: Research has shown increased risk of leukemia in children living near power lines, but results on adult hematological malignancies and brain tumors are inconclusive. This study found that exposure to extremely low frequency magnetic fields decreased the risk of most hematological neoplasms, with a positive association only observed for acute lymphocytic leukemia (ALL).
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2021)
Review
Environmental Sciences
Maria A. Karalexi, Christos F. Tagkas, Georgios Markozannes, Xanthippi Tseretopoulou, Antonio F. Hernandez, Joachim Schuez, Thorhallur Halldorsson, Theodora Psaltopoulou, Eleni Th Petridou, Ioanna Tzoulaki, Evangelia E. Ntzani
Summary: The meta-analysis of 55 eligible studies found that maternal environmental exposure to pesticides during pregnancy is associated with increased risk of childhood leukemia, especially acute lymphoblastic leukemia. Higher risks were observed for specific subtypes of pesticides like herbicides and insecticides. The evidence suggests a stronger association with leukemia for maternal exposure during pregnancy compared to childhood exposure.
ENVIRONMENTAL POLLUTION
(2021)
Article
Physics, Multidisciplinary
J. Misek, J. Jakus, K. Hamza Sladicekova, L. Zastko, M. Veternik, V. Jakusova, I. Belyaev
Summary: Cell phones expose significant parts of the human brain and head to extremely low frequency (ELF) magnetic fields (MF) classified by the IARC as a 2B carcinogen. Measurements and simulations showed that the ELF MF emitted by cell phones can reach levels comparable to those known to induce biological and health effects, including carcinogenesis. Understanding the exposure and combined effects of radiofrequency and ELF electromagnetic fields is important for future studies.
FRONTIERS IN PHYSICS
(2023)
Review
Environmental Sciences
Christelle Oltramare, Zakia Mediouni, Yara Shoman, Nancy B. Hopf, Halshka Graczyk, Aurelie Berthet
Summary: Few epidemiological studies have specific exposure determinants for assessing pesticide or plant protection product (PPP) exposures among agricultural workers, leading to possible undetected associations. Lack of consensus on exposure assessment methods and choice of determinants could contribute to this issue. A meta-analysis identified exposure determinants such as active ingredients, chemical classes, types of PPP, crops, tasks, frequencies, duration, lifetime exposure days, and intensity-weighted exposure days. Only six out of 17 associations between exposure determinants and health outcomes were found with moderate quality evidence. Standardized determinants for PPP exposures and harmonized data collection on exposure and health outcomes are recommended.
Review
Public, Environmental & Occupational Health
Masoud Rahmanian, Mohammad Javad Zare Sakhvidi, Amir Houshang Mehrparvar, Fariba Zare Sakhvidi, Payam Dadvand
Summary: In this study, the association between long-term occupational noise exposure and diabetes was evaluated through a systematic review and meta-analysis. The findings indicate a possible link between occupational noise exposure and diabetes, but the overall evidence is limited and of low quality. Therefore, further high-quality studies are needed to confirm this association.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2023)
Article
Environmental Sciences
Felix M. Onyije, Ann Olsson, Friederike Erdmann, Corrado Magnani, Eleni Petridou, Jacqueline Clavel, Lucia Miligi, Audrey Bonaventure, Daniela Ferrante, Sara Piro, Susan Peters, Roel Vermeulen, Hans Kromhout, Joachim Schuz
Summary: This study investigated the association between parental occupational exposures and the risk of childhood leukemia. The findings suggest a possible link between high paternal occupational exposure to crystalline silica and childhood leukemia. However, there were no significant associations observed for other occupational carcinogens. More research is needed to confirm these findings and explore the mechanistic pathways.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Environmental Sciences
Lemaan Rana, Sarah Dahlberg, Craig Steinmaus, Luoping Zhang
Summary: A systematic review and meta-analysis of human epidemiological studies revealed a potential causal link between benzene exposure and non-Hodgkin lymphoma, especially for diffuse large B-cell lymphoma.
LANCET PLANETARY HEALTH
(2021)
Review
Public, Environmental & Occupational Health
Maryam Bemanalizadeh, Mehri Khoshhali, Parvin Goli, Ibrahim Abdollahpour, Roya Kelishadi
Summary: This review highlights the potential association between parental occupational exposures, such as pesticides, solvents, and metals, and the risk of neurodevelopmental disorders (NDDs) in offspring. The findings suggest significant links between parental occupational exposures and attention deficit hyperactivity disorder, motor development or cognition disorders, and autism spectrum disorders in children. Further research is needed to determine the specific level of parental occupational exposures that are significantly associated with NDDs, and standardized outcome and exposure scales are recommended for future studies.
CURRENT ENVIRONMENTAL HEALTH REPORTS
(2022)
Article
Multidisciplinary Sciences
Tommaso Filippini, Elizabeth E. Hatch, Marco Vinceti
Summary: ALS is a neurodegenerative disease with a fatal prognosis and unknown etiology. Some environmental risk factors, including exposure to magnetic fields, have been suggested. Recent studies have shown positive associations in occupationally-exposed populations, but the link with residential exposure is still debated. Advanced biostatistical tools have found limited evidence of a small association between residential exposure to magnetic fields and ALS.
SCIENTIFIC REPORTS
(2021)
Article
Environmental Sciences
Julie Elbaek Pedersen, Johnni Hansen
Summary: The objective of this study was to examine the potential impact of parental exposure to chemicals at work on the risk of breast cancer in the next generations. The study found that maternal exposure to diesel exhaust and bitumen fumes, particularly during the perinatal period, increased the risk of breast cancer in female offspring. Additionally, cumulative exposure to benzo(a)pyrene, diesel exhaust, gasoline, and bitumen fumes was associated with an elevated risk. However, no significant association was observed between paternal occupational exposures and breast cancer in female offspring.
ENVIRONMENTAL RESEARCH
(2023)
Review
Pediatrics
Xiaolin Zhu, Ying Meng, Yang Yang, Ningning Feng
Summary: The meta-analysis of numerous studies found no significant association between maternal antibiotic intake during pregnancy and childhood acute lymphoblastic leukemia (ALL) risk. The consistent findings across subgroups suggest the need for further investigations to confirm the results and assess any risk differences of ALL by types of antibiotics.
EUROPEAN JOURNAL OF PEDIATRICS
(2022)
Article
Green & Sustainable Science & Technology
Liran Shmuel Raz-Steinkrycer, Jonathan Dubnov, Stelian Gelberg, Peng Jia, Boris A. Portnov
Summary: The study found that employees working near high-voltage power lines experienced both physiological and psychological effects, including feelings of weakness, headache, frustration, worry, eye pain, sleepiness, dizziness, and ear pain. Therefore, proximity to high-voltage power lines should be considered a public health issue.
Review
Environmental Sciences
Luciana Guimaraes Eiro, Maria Karolina Martins Ferreira, Deborah Ribeiro Frazao, Walessa Alana Braganca Aragao, Renata Duarte Souza-Rodrigues, Nathalia Carolina Fernandes Fagundes, Lucianne Cople Maia, Rafael Rodrigues Lima
Summary: This study reviewed the association between lead exposure and neurological damage through meta-analysis, finding that lead exposure is related to neurological impairment but with low certainty of evidence. Future studies should consider more reliable methods to address this issue.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Review
Public, Environmental & Occupational Health
Carlotta Zunarelli, Alessandro Godono, Giovanni Visci, Francesco S. Violante, Paolo Boffetta
Summary: Limited information is available on the carcinogenicity of asbestos on non-respiratory organs, and our study found no association between occupational asbestos exposure and the risk of kidney cancer.
EUROPEAN JOURNAL OF EPIDEMIOLOGY
(2021)
