Low expression of ASH2L protein correlates with a favorable outcome in acute myeloid leukemia

A phosphorylation switch on RbBP5 regulates histone H3 Lys4 methylation

(2015) Pamela Zhang et al.   GENES & DEVELOPMENT

Physical Interactions and Functional Coordination between the Core Subunits of Set1/Mll Complexes and the Reprogramming Factors

(2015) Zhenhua Yang et al.   PLoS One

WTAP is a novel oncogenic protein in acute myeloid leukemia

(2014) H Bansal et al.   LEUKEMIA

A SET-domain-independent role of WRAD complex in cell-cycle regulatory function of mixed lineage leukemia

(2014) Aamir Ali et al.   NUCLEIC ACIDS RESEARCH

The interaction of MYC with the trithorax protein ASH2L promotes gene transcription by regulating H3K27 modification

(2014) A. Ullius et al.   NUCLEIC ACIDS RESEARCH

The role of chromatin modifiers in normal and malignant hematopoiesis

(2013) J. S. Butler et al.   BLOOD

Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia

(2012) Catherine C. Smith et al.   NATURE

Abnormal expression of FLI1 protein is an adverse prognostic factor in acute myeloid leukemia

(2011) S. M. Kornblau et al.   BLOOD

Acute myeloid leukemia with mutated nucleophosmin (NPM1): Any hope for a targeted therapy?

(2011) Brunangelo Falini et al.   BLOOD REVIEWS

Crystal structure of the N-terminal region of human Ash2L shows a winged-helix motif involved in DNA binding

(2011) Yong Chen et al.   EMBO REPORTS

Protein-arginine Methyltransferase 1 (PRMT1) Methylates Ash2L, a Shared Component of Mammalian Histone H3K4 Methyltransferase Complexes

(2011) Jill S. Butler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans

(2011) Eric L. Greer et al.   NATURE

Crystal structure of the trithorax group protein ASH2L reveals a forkhead-like DNA binding domain

(2011) Sabina Sarvan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Identification of the methylation preference region in heterogeneous nuclear ribonucleoprotein K by protein arginine methyltransferase 1 and its implication in regulating nuclear/cytoplasmic distribution

(2010) Yuan-I Chang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Acute myeloid leukemia with mutated nucleophosmin (NPM1): is it a distinct entity?

(2010) B. Falini et al.   BLOOD

Highly Phosphorylated FOXO3A Is an Adverse Prognostic Factor in Acute Myeloid Leukemia

(2010) S. M. Kornblau et al.   CLINICAL CANCER RESEARCH

Ash2l interacts with Tbx1 and is required during early embryogenesis

(2010) Jason Z Stoller et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Protein-arginine Methyltransferase 1 Suppresses Megakaryocytic Differentiation via Modulation of the p38 MAPK Pathway in K562 Cells

(2010) Yuan-I Chang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans

(2010) Eric L. Greer et al.   NATURE

On the Mechanism of Multiple Lysine Methylation by the Human Mixed Lineage Leukemia Protein-1 (MLL1) Core Complex

(2009) Anamika Patel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Altered nucleophosmin transport in acute myeloid leukaemia with mutated NPM1: molecular basis and clinical implications

(2009) B Falini et al.   LEUKEMIA

The Human Trithorax Protein hASH2 Functions as an Oncoprotein

(2008) J. Luscher-Firzlaff et al.   CANCER RESEARCH

Transcription Regulation of the rRNA Gene by a Multifunctional Nucleolar Protein, B23/Nucleophosmin, through Its Histone Chaperone Activity

(2008) K. Murano et al.   MOLECULAR AND CELLULAR BIOLOGY

Multiple and Specific mRNA Processing Targets for the Major Human hnRNP Proteins

(2008) J. P. Venables et al.   MOLECULAR AND CELLULAR BIOLOGY

Protein Arginine Methyltransferase 5 Suppresses the Transcription of the RB Family of Tumor Suppressors in Leukemia and Lymphoma Cells

(2008) L. Wang et al.   MOLECULAR AND CELLULAR BIOLOGY

Transcription factor Ap2  associates with Ash2l and ALR, a trithorax family histone methyltransferase, to activate Hoxc8 transcription

(2008) C. C. Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA