Promiscuity, a Driver of Plant Cytochrome P450 Evolution?

Ancestral sequence reconstruction of the CYP711 family reveals functional divergence in strigolactone biosynthetic enzymes associated with gene duplication events in monocot grasses

(2022) Marcos H. Vinde et al.   NEW PHYTOLOGIST

Hydroxycinnamoyltransferase and CYP98 in phenolic metabolism in the rosmarinic acid-producing hornwort Anthoceros agrestis

(2022) Lucien Ernst et al.   PLANTA

Characterization of Cytochrome P450s with Key Roles in Determining Herbicide Selectivity in Maize

(2022) Melissa Brazier-Hicks et al.   ACS Omega

Expansion within the CYP71D subfamily drives the heterocyclization of tanshinones synthesis in Salvia miltiorrhiza

(2021) Ying Ma et al.   Nature Communications

Plant cytochrome P450 plasticity and evolution

(2021) Cecilie Cetti Hansen et al.   Molecular Plant

Functional characterization of cytochrome P450 CYP81A subfamily to disclose the pattern of cross-resistance in Echinochloa phyllopogon

(2020) Niña Gracel Dimaano et al.   PLANT MOLECULAR BIOLOGY

Rerouting plant terpene biosynthesis enables momilactone pathway elucidation

(2020) Ricardo De La Peña et al.   Nature Chemical Biology

DR HEPING HAN (Orcid ID : 00 Cytochrome P450 CYP81A10v7 in Lolium rigidum confers metabolic resistance to herbicides across at least five modes of action

(2020) Heping Han et al.   PLANT JOURNAL

Innate promiscuity of the CYP706 family of P450 enzymes provides a suitable context for the evolution of dinitroaniline resistance in weed

(2020) Fatemeh Abdollahi et al.   NEW PHYTOLOGIST

CYP76 Oxidation Network of Abietane Diterpenes in Lamiaceae Reconstituted in Yeast

(2019) Ulschan Bathe et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Independent evolution of rosmarinic acid biosynthesis in two sister families under the Lamiids clade of flowering plants

(2019) Olesya Levsh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Promiscuous CYP706A3 Reduces Terpene Volatile Emission from Arabidopsis Flowers, Affecting Florivores and the Floral Microbiome

(2019) Benoît Boachon et al.   PLANT CELL

Conversion of carlactone to carlactonoic acid is a conserved function of MAX1 homologs in strigolactone biosynthesis

(2018) Kaori Yoneyama et al.   NEW PHYTOLOGIST

Discovery, Biosynthesis and Stress-Related Accumulation of Dolabradiene-Derived Defenses in Maize

(2018) Sibongile Mafu et al.   PLANT PHYSIOLOGY

Substrate-induced conformational change in cytochrome P450 OleP

(2018) Giacomo Parisi et al.   FASEB JOURNAL

Gene Duplication Leads to Altered Membrane Topology of a Cytochrome P450 Enzyme in Seed Plants

(2017) Hugues Renault et al.   MOLECULAR BIOLOGY AND EVOLUTION

Total biosynthesis of the cyclic AMP booster forskolin from Coleus forskohlii

(2017) Irini Pateraki et al.   eLife

Intersection of the Roles of Cytochrome P450 Enzymes with Xenobiotic and Endogenous Substrates: Relevance to Toxicity and Drug Interactions

(2016) F. Peter Guengerich   CHEMICAL RESEARCH IN TOXICOLOGY

Carnosic acid biosynthesis elucidated by a synthetic biology platform

(2016) Codruta Ignea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Probing the promiscuity ofent-kaurene oxidases via combinatorial biosynthesis

(2016) Sibongile Mafu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolutionary interplay between sister cytochrome P450 genes shapes plasticity in plant metabolism

(2016) Zhenhua Liu et al.   Nature Communications

Optimization of recombinant expression enables discovery of novel cytochrome P450 activity in rice diterpenoid biosynthesis

(2015) Naoki Kitaoka et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Reconstructing the chemical diversity of labdane-type diterpene biosynthesis in yeast

(2015) Codruta Ignea et al.   METABOLIC ENGINEERING

Cytochrome P450 promiscuity leads to a bifurcating biosynthetic pathway for tanshinones

(2015) Juan Guo et al.   NEW PHYTOLOGIST

Survey of Human Oxidoreductases and Cytochrome P450 Enzymes Involved in the Metabolism of Xenobiotic and Natural Chemicals

(2014) Slobodan Rendic et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Dual Function of the Cytochrome P450 CYP76 Family from Arabidopsis thaliana in the Metabolism of Monoterpenols and Phenylurea Herbicides

(2014) R. Hofer et al.   PLANT PHYSIOLOGY

The Biosynthetic Pathway of Indole-3-Carbaldehyde and Indole-3-Carboxylic Acid Derivatives in Arabidopsis

(2014) C. Bottcher et al.   PLANT PHYSIOLOGY

Origins of P450 diversity

(2013) H. Sezutsu et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Characterization of CYP76M5–8 Indicates Metabolic Plasticity within a Plant Biosynthetic Gene Cluster

(2012) Qiang Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CYP701A8: A Rice ent-Kaurene Oxidase Paralog Diverted to More Specialized Diterpenoid Metabolism

(2012) Q. Wang et al.   PLANT PHYSIOLOGY

Evolution of Diterpene Metabolism: Sitka Spruce CYP720B4 Catalyzes Multiple Oxidations in Resin Acid Biosynthesis of Conifer Defense against Insects

(2011) B. Hamberger et al.   PLANT PHYSIOLOGY

CYP99A3: functional identification of a diterpene oxidase from the momilactone biosynthetic gene cluster in rice

(2010) Qiang Wang et al.   PLANT JOURNAL

Evolution of a Novel Phenolic Pathway for Pollen Development

(2009) M. Matsuno et al.   SCIENCE