JUN is a key transcriptional regulator of the unfolded protein response in acute myeloid leukemia

An initial phase of JNK activation inhibits cell death early in the endoplasmic reticulum stress response

(2016) Max Brown et al.   JOURNAL OF CELL SCIENCE

miR-216b regulation of c-Jun mediates GADD153/CHOP-dependent apoptosis

(2016) Zhenhua Xu et al.   Nature Communications

Endoplasmic Reticulum Stress-Activated Cell Reprogramming in Oncogenesis

(2015) E. Chevet et al.   Cancer Discovery

Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis

(2014) M. Lu et al.   SCIENCE

ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death

(2013) Jaeseok Han et al.   NATURE CELL BIOLOGY

Targeting the unfolded protein response in disease

(2013) Claudio Hetz et al.   NATURE REVIEWS DRUG DISCOVERY

Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

ATF4 is directly recruited by TLR4 signaling and positively regulates TLR4-trigged cytokine production in human monocytes

(2012) Chunyan Zhang et al.   Cellular & Molecular Immunology

HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis

(2012) Frederik Otzen Bagger et al.   NUCLEIC ACIDS RESEARCH

ENCODE Data in the UCSC Genome Browser: year 5 update

(2012) Kate R. Rosenbloom et al.   NUCLEIC ACIDS RESEARCH

Targeting inflammation by modulating the Jun/AP-1 pathway

(2011) H. B. Schonthaler et al.   ANNALS OF THE RHEUMATIC DISEASES

Molecular signatures database (MSigDB) 3.0

(2011) A. Liberzon et al.   BIOINFORMATICS

Protein disulfide isomerase blocks CEBPA translation and is up-regulated during the unfolded protein response in AML

(2011) S. Haefliger et al.   BLOOD

Altered Hematopoietic Cell Gene Expression Precedes Development of Therapy-Related Myelodysplasia/Acute Myeloid Leukemia and Identifies Patients at Risk

(2011) Liang Li et al.   CANCER CELL

AKT/FOXO Signaling Enforces Reversible Differentiation Blockade in Myeloid Leukemias

(2011) Stephen M. Sykes et al.   CELL

Extensive Pancreas Regeneration Following Acinar-Specific Disruption of Xbp1 in Mice

(2011) David A. Hess et al.   GASTROENTEROLOGY

The transcription factor c-Jun protects against sustained hepatic endoplasmic reticulum stress thereby promoting hepatocyte survival

(2011) Matthias Fuest et al.   HEPATOLOGY

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

(2011) Ira Tabas et al.   NATURE CELL BIOLOGY

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Modulating stress responses by the UPRosome: A matter of life and death

(2011) Ute Woehlbier et al.   TRENDS IN BIOCHEMICAL SCIENCES

Gene Expression and Genetic Variation in Response to Endoplasmic Reticulum Stress in Human Cells

(2010) Beth A. Dombroski et al.   AMERICAN JOURNAL OF HUMAN GENETICS

CHOP and AP-1 cooperatively mediate PUMA expression during lipoapoptosis

(2010) Sophie C. Cazanave et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation

(2010) Jiangbin Ye et al.   EMBO JOURNAL

Close association of RNA polymerase II and many transcription factors with Pol III genes

(2010) Debasish Raha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet

(2009) H. Dohner et al.   BLOOD

Activation of the Unfolded Protein Response Is Associated with Favorable Prognosis in Acute Myeloid Leukemia

(2009) J. A. Schardt et al.   CLINICAL CANCER RESEARCH

Unfolded protein response suppresses CEBPA by induction of calreticulin in acute myeloid leukaemia

(2009) Julian A. Schardt et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Differential regulation of CHOP translation by phosphorylated eIF4E under stress conditions

(2009) Yi-Jiun Chen et al.   NUCLEIC ACIDS RESEARCH

c-Jun Inhibits Thapsigargin-Induced ER Stress Through Up-Regulation of DSCR1/Adapt78

(2008) Peng Zhao et al.   EXPERIMENTAL BIOLOGY AND MEDICINE