Article
Multidisciplinary Sciences
Swee Ling Low, Yee Sin Leo, Yee Ling Lai, Sally Lam, Hwee Huang Tan, Judith Chui Ching Wong, Li Kiang Tan, Lee Ching Ng
Summary: Through evaluating the performance of eight commercially available ZIKV IgM and IgG assays on three testing platforms, it was found that these assays have varying sensitivities and specificities, with Diapro ZIKV IgM ELISA and Euroimmun ZIKV IgG ELISA showing high sensitivity and specificity in certain sample types.
Article
Biochemical Research Methods
Talia M. Quandelacy, Jessica M. Healy, Bradford Greening, Dania M. Rodriguez, Koo-Whang Chung, Matthew J. Kuehnert, Brad J. Biggerstaff, Emilio Dirlikov, Luis Mier-y-Teran-Romero, Tyler M. Sharp, Stephen Waterman, Michael A. Johansson
Summary: This study examines the estimation of Zika virus epidemic incidence using multiple indicators and models to account for reporting biases. By combining surveillance data and assumptions about reporting biases, it was estimated that approximately 890,000 individuals in Puerto Rico were infected with Zika in 2016, highlighting the importance of using multiple indicators for accurate estimation of epidemic incidence.
PLOS COMPUTATIONAL BIOLOGY
(2021)
Article
Medicine, General & Internal
Xintong Li, Berta Raventos, Elena Roel, Andrea Pistillo, Eugenia Martinez-Hernandez, Antonella Delmestri, Carlen Reyes, Victoria Strauss, Daniel Prieto-Alhambra, Edward Burn, Talita Duarte-Salles
Summary: The study found no safety signal between COVID-19 vaccines and immune mediated neurological events such as Bell's palsy, encephalomyelitis, Guillain-Barre syndrome, and transverse myelitis. However, an increased risk of these events was observed for individuals with SARS-CoV-2 infection.
BMJ-BRITISH MEDICAL JOURNAL
(2022)
Article
Microbiology
Abdul Aziz, Muhammad Suleman, Abdullah Shah, Ata Ullah, Farooq Rashid, Sikandar Khan, Arshad Iqbal, Sisi Luo, Liji Xie, Zhixun Xie
Summary: This study conducted a genome-wide mutational analysis of 175 ZIKV isolates and identified 257 different substitutions in various proteins. The study also found that coexisting mutations in the third domain of the envelope protein enhanced bonding with ZIKV-specific neutralizing antibodies. This study highlights the rapid accumulation of mutations in ZIKV during its global spread.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Clinical Neurology
Stephen Keddie, Julia Pakpoor, Christina Mousele, Menelaos Pipis, Pedro M. Machado, Mark Foster, Christopher J. Record, Ryan Y. S. Keh, Janev Fehmi, Ross W. Paterson, Viraj Bharambe, Lisa M. Clayton, Claire Allen, Olivia Price, Jasmine Wall, Annamaria Kiss-Csenki, Devi Priya Rathnasabapathi, Ruth Geraldes, Tatyana Yermakova, Joshua King-Robson, Maya Zosmer, Sanjeev Rajakulendran, Sheetal Sumaria, Simon F. Farmer, Ross Nortley, Charles R. Marshall, Edward J. Newman, Niranjanan Nirmalananthan, Guru Kumar, Ashwin A. Pinto, James Holt, Tim M. Lavin, Kathryn M. Brennan, Michael S. Zandi, Dipa L. Jayaseelan, Jane Pritchard, Robert D. M. Hadden, Hadi Manji, Hugh J. Willison, Simon Rinaldi, Aisling S. Carr, Michael P. Lunn
Summary: This study did not find any causal relationship between COVID-19 and GBS, and the incidence of GBS decreased during the pandemic, potentially due to lockdown measures reducing transmission of pathogens that induce GBS.
Article
Clinical Neurology
Stephen Keddie, Julia Pakpoor, Christina Mousele, Menelaos Pipis, Pedro M. Machado, Mark Foster, Christopher J. Record, Ryan Y. S. Keh, Janev Fehmi, Ross W. Paterson, Viraj Bharambe, Lisa M. Clayton, Claire Allen, Olivia Price, Jasmine Wall, Annamaria Kiss-Csenki, Devi Priya Rathnasabapathi, Ruth Geraldes, Tatyana Yermakova, Joshua King-Robson, Maya Zosmer, Sanjeev Rajakulendran, Sheetal Sumaria, Simon F. Farmer, Ross Nortley, Charles R. Marshall, Edward J. Newman, Niranjanan Nirmalananthan, Guru Kumar, Ashwin A. Pinto, James Holt, Tim M. Lavin, Kathryn M. Brennan, Michael S. Zandi, Dipa L. Jayaseelan, Jane Pritchard, Robert D. M. Hadden, Hadi Manji, Hugh J. Willison, Simon Rinaldi, Aisling S. Carr, Michael P. Lunn
Summary: Reports of Guillain-Barre syndrome during the COVID-19 pandemic did not show a causative association between COVID-19 and GBS. The incidence of GBS decreased during the pandemic, potentially due to lockdown measures reducing transmission of GBS-inducing pathogens. Intubation was more common in GBS cases with COVID-19, attributed to pulmonary involvement.
Article
Clinical Neurology
Sonja E. Leonhard, Susan Halstead, Suzannah B. Lant, Maria de Fatima Pessoa Militao de Albuquerque, Carlos Alexandre Antunes de Brito, Livia Brito Bezerra de Albuquerque, Mark A. Ellul, Rafael Freitas de Oliveira Franca, Dawn Gourlay, Michael J. Griffiths, Adelia Maria de Miranda Henriques-Souza, Maria I. de Morais Machado, Raquel Medialdea-Carrera, Ravi Mehta, Roberta da Paz Melo, Solange D. Mesquita, Alvaro J. P. Moreira, Lindomar J. Pena, Marcela Lopes Santos, Lance Turtle, Tom Solomon, Hugh J. Willison, Bart C. Jacobs, Maria L. Brito Ferreira
Summary: This study investigated the clinical phenotype and antibody signature of GBS patients following Zika virus and chikungunya virus outbreaks in Northeast Brazil. The majority of patients had evidence of recent arbovirus infection, with longer hospital stays observed in those infected with both Zika and chikungunya viruses.
JOURNAL OF THE NEUROLOGICAL SCIENCES
(2021)
Article
Multidisciplinary Sciences
Emilie Branche, Ying-Ting Wang, Karla M. Viramontes, Joan M. Valls Cuevas, Jialei Xie, Fernanda Ana-Sosa-Batiz, Norazizah Shafee, Sascha H. Duttke, Rachel E. McMillan, Alex E. Clark, Michael N. Nguyen, Aaron F. Garretson, Jan J. Crames, Nathan J. Spann, Zhe Zhu, Jeremy N. Rich, Deborah H. Spector, Christopher Benner, Sujan Shresta, Aaron F. Carlin
Summary: The study reveals that ZIKV infection alters the expression of inflammation- and metabolism-related genes to modulate the functions of dendritic cells.
NATURE COMMUNICATIONS
(2022)
Article
Multidisciplinary Sciences
Kelly Charniga, Zulma M. Cucunuba, Diana M. Walteros, Marcela Mercado, Franklyn Prieto, Martha Ospina, Pierre Nouvellet, Christl A. Donnelly
Summary: During the Zika virus epidemic in Colombia from 2015 to 2017, females had a higher cumulative incidence of ZVD than males, with cases more likely to occur in young adults aged 20 to 39 and pregnant females. Neurological complications among ZIKV patients were predominantly diagnosed as Guillain-Barre syndrome, with the highest incidence reported in individuals aged 75 and older. Better risk communication is needed for individuals living in or traveling to ZIKV-affected areas.
Article
Clinical Neurology
Francoise Lazarini, Annie Lannuzel, Andre Cabie, Vincent Michel, Yoann Madec, Hugo Chaumont, Isabelle Calmont, Mathilde Favrat, Xavier Montagutelli, Emmanuel Roze, Pierre-Marie Lledo
Summary: ZIKV infection is associated with poorer olfactory function in patients with GBS and also causes hyposmia in infected mice. These findings suggest that ZIKV should be considered as a virus affecting the olfactory system, and clinical evaluation of the olfactory system is important for ZIKV-infected patients.
EUROPEAN JOURNAL OF NEUROLOGY
(2022)
Review
Immunology
Thamil Vaani Komarasamy, Nur Amelia Azreen Adnan, William James, Vinod R. M. T. Balasubramaniam
Summary: This review provides a comprehensive overview of the role and mechanisms of Zika virus in the brain, including the study of target cells, cellular and molecular mechanisms. By analyzing the modulation of different host factors and the role of immune response and inflammatory process, a comprehensive understanding of Zika virus-induced neuroimmunopathogenesis is achieved.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Ricardo Paul Rodriguez de la Rosa, J. Oggun Cano-Torres, Sonia Rosales, Anke Paula Kleinert, Arturo Gomez, Fernando George, Jose George, Mariana Piedad Garcia, Gabriel Najera-Cancino, Paola Del Carmen Guerra-de-Blas, Pablo F. Belaunzaran-Zamudio, John Beigel, Guillermo Miguel Ruiz-Palacios
Summary: This study analyzed the clinical and epidemiological characteristics of patients with Guillain-Barre syndrome (GBS) during the Zika outbreak in Southern Mexico. The results showed a significant increase in the number of GBS patients during the Zika epidemic, with cases during the outbreak more frequently having a recent history of rash/conjunctivitis.
EPIDEMIOLOGY AND INFECTION
(2022)
Article
Biochemistry & Molecular Biology
Sang Il Kim, Sujeong Kim, Jung Min Shim, Hyo Jung Lee, So Young Chang, Seoryeong Park, Ji-Young Min, Wan Beom Park, Myoung-don Oh, Seungtaek Kim, Junho Chung
Summary: Zika virus infection can lead to neurological complications, but antibody therapy has shown to be effective. Researchers isolated neutralizing antibodies from recovered patients and successfully achieved complete protection against Zika virus in mice through a single dose treatment with these antibodies.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2021)
Article
Clinical Neurology
Johanna I. Hamel, Eric L. Logigian
Summary: This study retrospectively reviewed cases from 1999 to 2020 to describe the clinical, micronutrient, and electrophysiologic spectra and prognosis of acute nutritional axonal neuropathy (ANAN). The results showed that ANAN has a wide spectrum of manifestations and specific micronutrient deficiencies or risk factors do not predict neuropathy subtype. The prognosis of ANAN is guarded due to slow recovery of independent ambulation and residual neuropathic pain.
Editorial Material
Clinical Neurology
Jonah P. Zuflacht, Aimee K. Boegle
Summary: CIDP may present acutely, resembling GBS.
Article
Peripheral Vascular Disease
Yacob G. Tedla, Leonelo E. Bautista
AMERICAN JOURNAL OF HYPERTENSION
(2016)
Article
Public, Environmental & Occupational Health
Jung-Im Shin, Leonelo E. Bautista, Matthew C. Walsh, Kristen C. Malecki, F. Javier Nieto
PREVENTIVE MEDICINE
(2015)
Letter
Peripheral Vascular Disease
Yacob G. Tedla, Leonelo E. Bautista
AMERICAN JOURNAL OF HYPERTENSION
(2016)
Article
Peripheral Vascular Disease
Y. G. Tedla, L. E. Bautista
JOURNAL OF HUMAN HYPERTENSION
(2017)
Article
Medicine, General & Internal
Sharon P. Cooper, Eva M. Shipp, Deborah J. del Junco, Charles J. Cooper, Leonelo E. Bautista, Jeffrey Levin
SOUTHERN MEDICAL JOURNAL
(2016)
Review
Public, Environmental & Occupational Health
Leonelo E. Bautista
ANNALS OF EPIDEMIOLOGY
(2018)
Article
Public, Environmental & Occupational Health
Leonelo E. Bautista, Victor M. Herrera
Article
Public, Environmental & Occupational Health
Lina Wang, Leonelo E. Bautista
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2015)
Article
Cardiac & Cardiovascular Systems
Ahmad Jayedi, Kazem Rahimi, Leonelo E. Bautista, Milad Nazarzadeh, Mahdieh Sadat Zargar, Sakineh Shab-Bidar
Article
Clinical Neurology
Leonelo E. Bautista
JOURNAL OF THE NEUROLOGICAL SCIENCES
(2019)
Editorial Material
Biochemistry & Molecular Biology
Leonelo E. Bautista, Oscar L. Rueda-Ochoa
LIPIDS IN HEALTH AND DISEASE
(2021)
Article
Public, Environmental & Occupational Health
Luis Miguel Sosa Avila, Martha Lucia Diaz Galvis, Mayra Alejandra Jaimes Campos, Anyela Lozano-Parra, Laura Andrea Rodriguez Villamizar, Myriam Orostegui Arenas, Ruth Arali Martinez-Vega, Lina Maria Vera Cala, Leonelo E. Bautista
Summary: Saliva samples show similar or better accuracy than nasopharyngeal swaps (NPS) in detecting SARS-CoV-2 through RT-qPCR. Saliva specimens may be ideal for surveillance in the general population, especially in children and healthcare or other personnel in need of serial testing.
JOURNAL OF INFECTION AND PUBLIC HEALTH
(2022)
Article
Peripheral Vascular Disease
L. E. Bautista, P. K. Bajwa, M. M. Shafer, K. M. C. Malecki, C. A. McWilliams, A. Palloni
INTERNATIONAL JOURNAL CARDIOLOGY HYPERTENSION
(2019)
Letter
Medicine, General & Internal
Leonelo E. Bautista
