4.8 Review

A medical-toxicological view of tattooing

Journal

LANCET
Volume 387, Issue 10016, Pages 395-402

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/S0140-6736(15)60215-X

Keywords

-

Funding

  1. BfR

Ask authors/readers for more resources

Long perceived as a form of exotic self-expression in some social fringe groups, tattoos have left their maverick image behind and become mainstream, particularly for young people. Historically, tattoo-related health and safety regulations have focused on rules of hygiene and prevention of infections. Meanwhile, the increasing popularity of tattooing has led to the development of many new colours, allowing tattoos to be more spectacular than ever before. However, little is known about the toxicological risks of the ingredients used. For risk assessment, safe intradermal application of these pigments needs data for toxicity and biokinetics and increased knowledge about the removal of tattoos. Other concerns are the potential for phototoxicity, substance migration, and the possible metabolic conversion of tattoo ink ingredients into toxic substances. Similar considerations apply to cleavage products that are formed during laser-assisted tattoo removal. In this Review, we summarise the issues of concern, putting them into context, and provide perspectives for the assessment of the acute and chronic health effects associated with tattooing.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.8
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

Editorial Material Dermatology

Nail Lichen Planus in Skin of Color

Nicolas Kluger

JOURNAL OF CUTANEOUS MEDICINE AND SURGERY (2023)

Article Toxicology

HBM4EU chromates study-the measurement of hexavalent and trivalent chromium in exhaled breath condensate samples from occupationally exposed workers across Europe

Elizabeth Leese, Kate Jones, Beatrice Bocca, Radia Bousoumah, Argelia Castano, Karen S. Galea, Ivo Iavicoli, Marta Esteban Lopez, Veruscka Leso, Sophie Ndaw, Simo P. Porras, Flavia Ruggieri, Paul T. J. Scheepers, Tiina Santonen

Summary: The aim of this study was to investigate the practicality of using exhaled breath condensate (EBC) as a biological matrix for detecting and measuring hexavalent chromium (Cr(VI)) and trivalent chromium (Cr(III)) in occupational workers. EBC samples were collected from workers in various countries and analyzed using hyphenated chromatography systems with inductively coupled plasma - mass spectrometry (ICP-MS). The results showed that occupationally exposed workers had significantly higher levels of Cr(VI) and Cr(III) compared to the control group. Chrome platers had the highest levels of Cr(VI) in their EBC samples, and both Cr(VI) and Cr(III) levels increased significantly after working. This study suggests that EBC can be a valid and non-invasive biological matrix for assessing occupational exposure to Cr(VI) and Cr(III).

TOXICOLOGY LETTERS (2023)

Article Environmental Sciences

Occupational Exposure to Metal Engineered Nanoparticles: A Human Biomonitoring Pilot Study Involving Italian Nanomaterial Workers

Beatrice Bocca, Beatrice Battistini, Veruscka Leso, Luca Fontana, Stefano Caimi, Mauro Fedele, Ivo Iavicoli

Summary: This study developed a methodology for human biomonitoring, based on SP-ICP-MS, to assess the exposure of workers involved in nanomaterial activities. The results showed the presence of ENPs in both workers and controls, suggesting that extra-professional exposure is a potential source of ENPs.

TOXICS (2023)

Article Health Care Sciences & Services

Development and Validation of the Epidemiological Tattoo Assessment Tool to Assess Ink Exposure and Related Factors in Tattooed Populations for Medical Research: Cross-sectional Validation Study

Milena Foerster, Lucas Dufour, Wolfgang Baeumler, Ines Schreiver, Marcel Goldberg, Marie Zins, Khaled Ezzedine, Joachim Schuez

Summary: This study developed and validated a questionnaire tool for assessing tattoo ink exposure in tattooed populations for use in large epidemiological cohort studies. The results showed that self-reporting of tattoo ink exposure led to an overestimation of tattoo size, which calls for further research to identify potential influential factors and predictive patterns.

JMIR FORMATIVE RESEARCH (2023)

Review Allergy

Hypersensitivity to permanent tattoos: Literature summary and comprehensive review of patch tested tattoo patients 1997-2022

Steffen Schubert, Nicolas Kluger, Ines Schreiver

Summary: The study shows that tattoo allergy cannot be reliably diagnosed with current knowledge through patch testing. The weak penetration and slow haptenization of pigments, unavailability of pigments as test allergens, and lack of knowledge regarding relevant epitopes hinder the diagnosis of tattoo allergy. Sensitization to metals is associated with various tattoo complications, but may not be clinically relevant. The absence of binders and industrial biocides in ink declarations highlights the need for patch testing. The effectiveness of banning Pigment Green 7 and Pigment Blue 15:3 in the EU remains unsubstantiated by the presented data.

CONTACT DERMATITIS (2023)

Letter Dermatology

Potential applications of ChatGPT in dermatology

Nicolas Kluger

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2023)

Letter Dermatology

Tattoos, tattooists, moles and melanomas

Nicolas Kluger

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2023)

Editorial Material Dermatology

Digital necrosis in the Isenheim altarpiece (1512-1516)

Nicolas Kluger, Guiliano Brandozzi

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2023)

Editorial Material Dermatology

A case of hidradenitis suppurativa in a 19th-century painting at the Leopold Museum?

Nicolas Kluger

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2023)

Letter Dermatology

Skin toxicity of enfortumab vedotin: Proposal of a specific management algorithm

Saskia Ingen-Housz-Oro, Yannick S. Elshot, Sonia Segura, Antoine Marchand, Damien Pouessel, Nicolas Kluger, Giselle de Barros Silva, Ariadna Ortiz-Brugues, Marine Aubert, Carolina Saldana, Dimitrios Mavroudis, Estelle Burle, Emilie Tournier, Dimitra Koumaki, Vincent Sibaud

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2023)

Letter Dermatology

Laser tattoo removal and risks of cancer: A joint statement of the EADV tattoo and body art task force, European Society for Lasers and Energy-Based Devices (ESLD) and la Societe Francaise des lasers en Dermatologie

Nicolas Kluger, Ashraf Badawi, Hans-Joachim Laubach, Albert Wolkerstorfer, Hugues Cartier

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2023)

Letter Dermatology

Reflections on frontal fibrosing alopecia in artworks

Nicolas Kluger

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2023)

Article Dermatology

Investigation of Adverse Reactions in Tattooed Skin through Histological and Chemical Analysis

Bernadett Kurz, Ines Schreiver, Katherina Siewert, Birgit Haslboeck, Katharina T. Weiss, Julia Hannemann, Bianca Berner, Maria Isabel von Eichborn, Mark Berneburg, Wolfgang Baeumler

Summary: The number of adverse reactions in tattooed skin has increased along with the popularity of tattoos. The substances in tattoo colourants can provoke allergic or granulomatous reactions, but it is often difficult to identify the triggering substances. By analyzing skin samples and tattoo colourants, researchers found that red tattoos were the most common cause of adverse reactions, mainly due to Pigment Red (P.R.) 170. Some patients showed improvement after treatment. This approach may contribute to the development of safer tattoo colourants in the future.

DERMATOLOGY (2023)

No Data Available