Article
Psychology, Developmental
Stephanie Y. Shire, Wendy Shih, Terri Barriault, Connie Kasari
Summary: Caregiver-mediated intervention models for families with children with autism are increasingly being tested in efficacy trials, but few have been implemented in the community. This pilot project in partnership with a publicly funded intervention agency in Canada explored intervention strategies and follow-up supports, finding significant gains for caregivers in supporting children's joint engagement.
Article
Public, Environmental & Occupational Health
Jun Hyung Kim, Kurt Hahlweg, Wolfgang Schulz
Summary: Improving early childhood parenting can reduce adolescent bullying behavior, especially for boys and more aggressive forms of bullying.
SOCIAL SCIENCE & MEDICINE
(2021)
Article
Psychology, Developmental
Daina M. Tagavi, Catherine C. Dick, Shana M. Attar, Lisa Ibanez, Wendy L. Stone
Summary: This study examined the feasibility of implementing the Screening Tool for Autism in Toddlers within Early Intervention settings. The results suggest the potential use of the tool and propose an implementation model in which specific providers serve as a screening point-person. Future research should aim to identify the characteristics of agencies or providers that might be best suited for using the screening tool.
Article
Sport Sciences
Eline Coppens, Nikki Rommers, Farid Bardid, Frederik J. A. Deconinck, Kristine De Martelaer, Eva D'Hondt, Matthieu Lenoir
Summary: The study found that the Multimove intervention did not have a long-term effect on the development of motor competence, but participation in organized sports had a positive influence on the evolution of motor competence over time.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2021)
Article
Nutrition & Dietetics
Miguel A. Rojo-Tirado, Pedro J. Benito, Jonatan R. Ruiz, Francisco B. Ortega, Blanca Romero-Moraleda, Javier Butragueno, Laura M. Bermejo, Eliane A. Castro, Carmen Gomez-Candela
Summary: Comparing different exercise modalities combined with diet intervention on body composition in overweight and obese adults, the study found that the combined strength and endurance group had lower levels of fat mass percentage both immediately after intervention and 3 years later compared to the other groups.
Article
Psychology, Developmental
Sophie Carruthers, Andrew Pickles, Tony Charman, Helen McConachie, Ann Le Couteur, Vicky Slonims, Patricia Howlin, Rachel Collum, Erica Salomone, Hannah Tobin, Isobel Gammer, Jessica Maxwell, Catherine Aldred, Jeremy Parr, Kathy Leadbitter, Jonathan Green
Summary: This study investigates the mechanism by which the parent-mediated Paediatric Autism Communication Therapy (PACT) intervention achieves sustained effects on autistic child outcomes. It finds that increased communication initiation between the autistic child and their caregiver is largely responsible for the long-term effects on behavior and adaptive outcomes.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2023)
Article
Chemistry, Multidisciplinary
Matteo Nagni, Filippo Pirani, Bianca D'Orto, Francesco Ferrini, Paolo Cappare
Summary: This retrospective clinical study evaluated the clinical and radiographic outcomes of full-arch implant prosthetic rehabilitations supported by six axial implants or four implants placed according to the All-on-Four protocol. The results showed that immediate implant-retained prosthetic rehabilitations supported by either six axial implants or four fixtures could be a valid therapeutic alternative for edentulous patients, providing functional and aesthetic restoration and improving patient acceptance.
APPLIED SCIENCES-BASEL
(2023)
Article
Psychology, Clinical
Maureen McHugo, Suzanne Avery, Kristan Armstrong, Baxter P. Rogers, Simon N. Vandekar, Neil D. Woodward, Jennifer Urbano Blackford, Stephan Heckers
Summary: This study suggests that hippocampal dysfunction in early psychosis does not worsen over a period of 2 years and highlights the need for longer-term longitudinal studies.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Nutrition & Dietetics
Francesca Sanchez-Martinez, Silvia Brugueras, Gemma Serral, Sara Valmayor, Olga Juarez, Maria Jose Lopez, Carles Ariza
Summary: The study aimed to evaluate the effectiveness of a school-based intervention program on childhood obesity. The results showed that children in the intervention group made positive changes in various aspects of diet and exercise habits, with significantly higher scores in global activity and overall improvement compared to the control group.
Article
Pediatrics
Sergio Serrada-Tejeda, Patricia Sanchez-Herrera-Baeza, Rosa M. Martinez-Piedrola, Nuria Maximo-Bocanegra, Nuria Trugeda-Pedrajo, M. Pilar Rodriguez-Perez, Gemma Fernandez-Gomez, Marta Perez-de-Heredia-Torres
Summary: The aim of this study was to determine whether changes in sensory reactivity skills occur in individuals with PMS after one year of follow-up. The results showed significant changes in tactile hyperreactivity (p = 0.003), but no significant differences in other variables. Understanding the evolution of sensory reactivity skills can help individuals with PMS adapt to behavioral changes and design targeted interventions.
Article
Psychiatry
Eva-Maria Pichler, Niklaus Stulz, Lea Wyder, Simone Heim, Birgit Watzke, Wolfram Kawohl
Summary: The study found that the IPS method in helping individuals with mental health illnesses reintegrate into the workforce provided better employment rates, longer job tenure, and higher salaries compared to traditional methods. However, after a 6-year follow-up, it was discovered that there were no significant differences between the IPS intervention and treatment as usual in terms of employment rates, workload, job tenure, and salary.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Pediatrics
Michele Ybarra, Margaret Rosario, Elizabeth Saewyc, Carol Goodenow, Shira Dunsiger
Summary: Research found that LGB+ girls are more likely to be pregnant during adolescence, but inclusive pregnancy prevention programs for this group are lacking. A 5-month intervention called Girl2Girl was conducted and found to be associated with increased rates of protected sex and use of birth control among LGB+ girls. The long-term outcomes at 17 months post-intervention showed that Girl2Girl can help sustain pregnancy preventive behaviors for LGB+ girls.
Article
Hematology
Sattva S. Neelapu, Caron A. Jacobson, Armin Ghobadi, David B. Miklos, Lazaros J. Lekakis, Olalekan O. Oluwole, Yi Lin, Ira Braunschweig, Brian T. Hill, John M. Timmerman, Abhinav Deol, Patrick M. Reagan, Patrick Stiff, Ian W. Flinn, Umar Farooq, Andre H. Goy, Peter A. McSweeney, Javier Munoz, Tanya Siddiqi, Julio C. Chavez, Alex F. Herrera, Nancy L. Bartlett, Adrian A. Bot, Rhine R. Shen, Jinghui Dong, Kanwarjit Singh, Harry Miao, Jenny J. Kim, Yan Zheng, Frederick L. Locke
Summary: In the phase 2 trial ZUMA-1, long-lasting responses were observed in refractory large B-cell lymphoma patients treated with axicabtagene ciloleucel (axi-cel) autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy after 5 years of follow-up. The study showed an objective response rate of 83% and a median overall survival of 25.8 months, with ongoing responses in 31% of patients at data cutoff. No new safety concerns were identified, and B-cell recovery was observed in the majority of patients. These findings highlight the potential effectiveness of axi-cel in aggressive B-cell lymphomas.
Article
Public, Environmental & Occupational Health
Sandra Ana Czarnobay, Caroline Kroll, Cecilia Burigo Correa, Silmara S. B. S. Mastroeni, Marco F. Mastroeni
Summary: This study examined the predictors of excess body weight in mother-child pairs after delivery, and found that excessive pre-pregnancy BMI, excessive gestational weight gain, and large-for-gestational age infants were strong predictors of concurrent excess body weight in mother-child pairs. This highlights the importance of implementing targeted public policies before and during pregnancy to prevent excess body weight in both mother and child.
JOURNAL OF PUBLIC HEALTH
(2023)
Article
Pharmacology & Pharmacy
Andrew Barron, Jennifer Chung, Robin E. Ferner, Maria Leandro, Saloni Maru, Andrew Scourfield, Robert Urquhart, Reecha Sofat
Summary: Health systems promote the use of biosimilars for their cost-effectiveness. The speed and completeness of biosimilar adoption are indicators of efficiency. This study examines the adoption of biosimilars at a hospital trust and compares its efficiency to the national average. The results show a faster and more complete switch to biosimilars, leading to significant cost savings. Additionally, patients who reverted to their original biologics after switching to biosimilars showed improved short-term and long-term outcomes.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
(2023)
Article
Education, Special
Hannah Waddington, Amarie Carnett, Larah van der Meer, Jeff Sigafoos
Summary: This study examined the effects of teaching two autistic children to request the continuation of actions using an iPad-based SGD during social interactions. The results showed that systematic instructional procedures were effective in improving the children's requesting behavior and that this skill generalized to other environments.
ADVANCES IN NEURODEVELOPMENTAL DISORDERS
(2023)
Article
Psychology, Developmental
Hannah Waddington, Ella Macaskill, Andrew J. O. Whitehouse, Wesley Billingham, Gail A. Alvares
Summary: This study found that parent-reported atypical development in a child's first year is associated with age of diagnosis and age when parents first consulted a specialist. Atypical development in most domains is linked to an earlier age when specialist consultation is needed.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2023)
Article
Psychology, Developmental
Willow J. Sainsbury, Kelly Carrasco, Andrew J. O. Whitehouse, Hannah Waddington
Summary: Autism and attention-deficit/hyperactivity disorder (ADHD) often occur together. This study found that children with both autism and ADHD were diagnosed with ADHD earlier and autism later. Parents of children with both disorders reported less atypical development in language and social behaviors, experienced longer wait times for diagnosis, and saw more types of specialists before getting a diagnosis compared to parents of children with just autism.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2023)
Correction
Psychology, Developmental
Willow J. Sainsbury, Kelly Carrasco, Andrew J. O. Whitehouse, Hannah Waddington
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2023)
Review
Psychology, Developmental
Willow J. Sainsbury, Kelly Carrasco, Andrew J. O. Whitehouse, Lauren McNeil, Hannah Waddington
Summary: This systematic review found that when ASD and ADHD co-occur, ASD is typically diagnosed later and ADHD is typically diagnosed earlier. Further research is needed to understand the factors influencing the delayed diagnosis of ASD and the earlier diagnosis of ADHD when the two conditions are present together.
REVIEW JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2023)
Article
Rehabilitation
Jessica Tupou, Chevelle Ataera, Hannah Waddington
Summary: This pilot study explored the experience of a Maori parent whose child participated in a play-based autism support program. The participant's experience with the program was largely positive, but incorporating Maori resources and activities into the program may be beneficial for Maori.
RESEARCH AND PRACTICE IN INTELLECTUAL AND DEVELOPMENTAL DISABILITIES
(2023)
Review
Psychology, Developmental
David Trembath, Kandice Varcin, Hannah Waddington, Rhylee Sulek, Cathy Bent, Jill Ashburner, Valsamma Eapen, Emma Goodall, Kristelle Hudry, Jacqueline Roberts, Natalie Silove, Andrew Whitehouse
Summary: This article reports the findings of an umbrella review of 58 systematic reviews of non-pharmacological interventions for autistic children. The results show that some interventions have positive therapeutic effects, but no single intervention has a positive effect on all child and family outcomes. The influence of child and delivery characteristics on the effects is unclear. These findings provide evidence-based decision-making guidance for parents, practitioners, and policymakers in selecting interventions and highlight the importance of individualized approaches in the absence of clear and consistent evidence.
Review
Psychology, Developmental
Carla Wallace-Watkin, Jeff Sigafoos, Hannah Waddington
Summary: Families of autistic children from underserved populations participate in support services at lower rates than other families. Financial pressures, geographic location, and service flexibility are the main barriers for them to obtain support services.
Article
Anesthesiology
J. E. O'Carroll, L. Zucco, E. Warwick, G. Arbane, S. R. Moonesinghe, K. El-Boghdadly, N. Guo, B. Carvalho, P. Sultan
Summary: To assess postpartum recovery in patients receiving peripartum anaesthetic interventions, a UK-based multicentre cohort study was conducted. Data on recovery metrics, including quality of recovery measures, pain scores, length of hospital stay, readmission rates, and complications, were collected at 1 and 30 days postpartum. The study included 1638 patients, and the results showed variations in recovery outcomes based on delivery mode and identified a subset of patients who experienced complications and readmissions.
Article
Medicine, General & Internal
Laurie McLay, Lisa Marie Emerson, Hannah Waddington, Jenna van Deurs, Jolene Hunter, Neville Blampied, Aaron Hapuku, Sonja Macfarlane, Nicholas Bowden, Lauren van Noorden, Mandy Rispoli
Summary: This study aims to evaluate the effectiveness and social validity of telehealth-delivered, caregiver-implemented, child-focused naturalistic developmental behavioral interventions (NDBI) and caregiver-focused acceptance and commitment therapy (ACT) on improving autistic children's social communication and caregiver well-being. The study will use a randomized, single-blind clinical trial with three parallel arms and recruit a minimum of 78, 2-5-year-old autistic children and their families. The findings will be disseminated through peer-reviewed journals and conferences, as well as shared with stakeholders and healthcare professionals.
Article
Psychology, Developmental
Carla Wallace-Watkin, Jeff Sigafoos, Lisa Woods, Hannah Waddington
Summary: We conducted a survey among New Zealand parents of autistic children to examine the barriers and facilitators they face when accessing support services, with a focus on the impact of family's financial resources. A total of 173 completed surveys were analyzed. Participants reported that service pathway factors were the most significant barrier, while facilitators related to providers were most helpful. Lower family income was associated with a higher number of reported barriers. Parents with lower family income and non-binary children rated the extent of barriers higher. Parents of younger or non-speaking autistic children reported a greater number of facilitators. The implications of these findings for support service delivery and future research are discussed.
Article
Psychology, Developmental
Hannah Waddington, Hannah Minnell, Lee Patrick, Larah van der Meer, Ruth Monk, Lisa Woods, Andrew J. O. Whitehouse
Summary: This study investigated the perspectives of 87 autistic adults, 159 parents of autistic children, and 80 clinical professionals on support goals for young autistic children. The highest priority goals across participant groups were related to the adult supporting the child, the reduction and replacement of harmful behaviors, and improving child quality of life. Goals related to child autism characteristics, play, and academic skills were rated as the lowest priority.
Article
Ethnic Studies
Jessica Tupou, Chevelle Rangimaria Ataera, Hannah Waddington
Summary: This mixed-methods study aimed to explore the experiences and goals of Maori parents and whanau caring for young autistic children. Data were collected via a focus group and an online questionnaire, with findings highlighting the value of considering parent and whanau voices, especially those from Indigenous communities.
ALTERNATIVE-AN INTERNATIONAL JOURNAL OF INDIGENOUS PEOPLES
(2023)
Article
Education, Special
Anastasia Sawchak, Hannah Waddington, Jeff Sigafoos
Summary: This study evaluated the effectiveness of a systematic instructional package for teaching a four-step SGD-based requesting and social communication sequence to minimally verbal autistic children. The results showed that the intervention led to accurate performance of the sequence, as well as generalization, maintenance, and discriminated/functional use of the skills.
ADVANCES IN NEURODEVELOPMENTAL DISORDERS
(2023)
Article
Education, Special
Willow J. Sainsbury, Chris J. Bowden, Kelly D. Carrasco, Andrew J. O. Whitehouse, Hannah Waddington
Summary: This study compares the experiences of parents whose children have been diagnosed with autism, attention deficit hyperactivity disorder (ADHD), or both. The findings reveal common and unique themes across these neurodevelopmental conditions, indicating the need for changes in the diagnostic process.
INTERNATIONAL JOURNAL OF DEVELOPMENTAL DISABILITIES
(2023)